Tom Vondriska

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Tom Vondriska

Tom Vondriska

@VondriskaLab

Chromatin, heart disease, and other stuff see thomasvondriska dot substack dot com

Los Angeles Katılım Nisan 2020
2.1K Takip Edilen3K Takipçiler
Andrew White 🐦‍⬛
Andrew White 🐦‍⬛@andrewwhite01·
Our agents can make real discoveries! One year of peer-review, but this work was accepted in @Nature . Huge congrats to the team, especially @agreeb66 who patiently worked on follow-up experiments for months. And here's a pics of some authors in the lab where we did the work
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David Braun
David Braun@BraunMDPhD·
We are hiring! We are specifically looking for a postgraduate associate - someone who has recently finished university and is ultimately looking to apply to medical school or graduate school. It is a TWO YEAR clinical/translational position, where you will be interacting closely with patients, involved in translational clinical trials, and working hands on in the lab and with clinical databases. The ideal candidate is a great communicator, organized, and enthusiastic about patient-oriented clinical and lab research. You will get dedicated mentoring not just on the science and clinic, but also on career/professional development as well. We are looking for someone to start ASAP! More information here: postdocs.yale.edu/posts/2026-01-… Please help to spread the word and RT! @DrChoueiri @VanAllenLab @tompowles1 @YaleCancer @YaleMed @SmilowCancer @kidneycan @OncoAlert @OncLive @KidneyCancer @A_P_S_A @cure_today @yalepathology @Yale_Urology @DrYukselUrun @MarkDSiegel1 @OncBrothers @DrKarineTawagi
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Thomas Massie for Congress
I did not see this coming, but my election has become an inflection point for our whole country. Today we make history. Will you be part of this historic day by voting, calling friends who can vote, posting to social media, or making a donation? Spread the word fellow patriots!
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Jason Sheltzer
Jason Sheltzer@JSheltzer·
My lab at @Stanford is looking to hire postdocs for multiple projects on cancer biology and therapeutics. Our recent work has uncovered some truly remarkable mechanisms for cytotoxic small molecules and we're looking to build on this research. If interested, see below:
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Thomas Massie for Congress
Thomas Massie for Congress@MassieforKY·
In less than four days, our Moneybomb has reached $847,950 thanks to thousands of patriots across the country. Soon we will buy the final tv ads & mail pieces for the last week of the campaign. massiemoneybomb.com is still live and these donations are critical. Thank you!
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Department of Medicine at UCLA Health
Congratulations to Dr. Aditya Bardia on his election to the American Society for Clinical Investigation! A leader in precision medicine, Dr. Bardia’s innovative work in antibody-drug conjugates and liquid biopsies is transforming cancer care. Learn more: uclahs.fyi/4vFWGgp
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Abberior
Abberior@Abberior·
DNA is not static inside the nucleus, and its dynamics play a crucial role in gene activation and DNA repair. By combining MINFLUX with conventional tracking methods, Mazzocca et al. have now resolved chromatin motion across an exceptional dynamic range—from microseconds to minutes: nature.com/articles/s4159… 🔬 Key findings: • Chromatin exhibits highly constrained, subdiffusive motion • Local DNA regions can interact rapidly • Long-range interactions occur very slowly and are therefore limited • Structural features such as loop extrusion strongly restrict mobility Congratulations to Matteo Mazzocca, Anders S. Hansen and all authors for refining our understanding of genome organization and its impact on gene regulation and DNA repair.
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Department of Medicine at UCLA Health
Congratulations to Dr. Dennis Slamon on his election to the Association of American Physicians! His groundbreaking discoveries, including the development of Herceptin, have saved millions of lives and revolutionized cancer care. Read the full story here: uclahs.fyi/48apDal
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Tom Vondriska
Tom Vondriska@VondriskaLab·
@LocasaleLab both statements could be true...with some specific context. hers was wildly devoid of any context and your rebuttal missed an opportunity to provide it. 'aberrant glucose metabolism' does little to explain how one should think about proper management of an essential molecule
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Jason Locasale
Jason Locasale@LocasaleLab·
She’s actually on point here. Altered glucose metabolism has long been known to be at the heart of Diabetes, which has killed millions of people. Over the past 20 years, it’s also become clear that aberrant glucose metabolism is fundamental to Cancer, Aging and Inflammation. I’ve spent much of my career publishing on the last three.
Neil Stone@DrNeilStone

Ladies and gentlemen your nominee for Surgeon General

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Aaron Gwyn
Aaron Gwyn@AmericanGwyn·
My Advanced Readers Edition of NO COUNTRY FOR OLD MEN that Knopf sent me when I reviewed it in 2005. It differs in really interesting ways from the finished version of Cormac’s novel. (Apparently these go for big money now).
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Anthony J. Covarrubias
Anthony J. Covarrubias@ACovarrubiasPhD·
Happy to share that our artwork was selected for the Cover of the April Volume of @NatureAging . Huge shout-out to Christina Deng, a grad student and a co-author of our manuscript, who created this beautiful image of macrophage senescence and tissue inflammation.
Nature Aging@NatureAging

🗞️Our April issue is live! ✨the cover art depicts work on macrophage senescence as postage stamps 🎨 the issue includes studies on improving vaccine efficacy in aging, endogenous regulation of cGAS, repurposing drugs for vascular dementia & much more nature.com/nataging/volum…

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Longzhi Tan
Longzhi Tan@tanlongzhi·
3D genome architecture underlies health & disease, but its biochemical basis is hard to study at scale. We present Plate-C: a screening platform that profiles thousands of whole-genome 3D maps in a day ($4 each), discovering many pathways that rewire DNA: biorxiv.org/content/10.648…
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Department of Medicine at UCLA Health
Discover groundbreaking research conducted by the AIDS Clinical Trials Group (ACTG) under UCLA’s leadership. Learn about key studies that advanced HIV treatments, prevention strategies and global infectious disease care. Watch here: uclahs.fyi/3POmWVH
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