Kevin Keane

196 posts

Kevin Keane

Kevin Keane

@KevinKeane92

Urology Trainee 🇮🇪, PhD Candidate @UWA 🇦🇺 Research Fellow Fiona Stanley Hospital Perth, @BURSTurology Committee member-Liverpool FC/Limerick Hurling Fanatic

Ireland Katılım Ocak 2020
1.1K Takip Edilen476 Takipçiler
Kevin Keane retweetledi
UroToday.com
UroToday.com@urotoday·
Gemcitabine-docetaxel intravesical synchronous CO-administration (G-DISCO); A first-in-human evaluation of synchronous gemcitabine-docetaxel. Presented by Kevin Keane, MB, BCh, BAO, MCh, MRCSi @uwanews. #EAU26 written coverage by @RKSayyid @UAUrology > bit.ly/4lDKlF1 @Uroweb
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Kevin Keane
Kevin Keane@KevinKeane92·
Delighted to present the results of the 1st in human Phase 1 #GDISCO trial assessing synchronous intravesical administration of Gem-Doce in HR-NMIBC at #EAU26 @ANZUPtrials @uwanews
Rashid K. Sayyid@RKSayyid

G-DISCO: Ph 1 study of synchronous intravesical Gem/Doce in BCG-unresponsive NMIBC (n=15) 💡Why this matters: Sequential Gem/Doce widely used, but sequencing based on theory rather than bladder-specific data. Synchronous delivery may shorten treatment time and improve efficiency. Feasibility: 🔹93% received ≥4 instillations with dwell >60 min 🔹87% completed all 6 instillations 3-mo outcomes (n=13): 🔹CR: 62% 🔹HG recurrence: 23% 🔹LG recurrence: 15% 📌3-mo HG RFS: 77% Supports further evaluation in Ph 2 G-DISCOTEQ trial @urotoday #EAU26

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Kevin Keane
Kevin Keane@KevinKeane92·
📢SUBDUE-3 is now officially open at #FionaStanleyHospital. Using zirconium-labelled PET imaging, we aim to characterise local and systemic biodistribution following targeted injection of durvalumab into the sub-urothelium. Thanks to all collaborators @ANZUPtrials @uwanews
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Phil McEntee
Phil McEntee@phildmcentee·
Hanging up his clogs having worked in The Mater for as long as I have been alive. I’m so proud of all he has achieved and the legacy he leaves behind. Delighted to have had the chance to see him in action and will always cherish the memories of getting to scrub in together
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Tom Powles
Tom Powles@tompowles1·
Perioperative EVP shows ⬆️ EFS,OS & pCR vs cystectomy alone in high risk cisplatin ineligible MIBC (KN901). Highly active systemic vs surgery will rescue many patients with aggressive micrometastatic disease. CRs for EVP=30% in M1 but should be ⬆️ in MIBC biospace.com/press-releases…
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Roger Li
Roger Li@UrogerliMD·
Dickon Hayne presenting the results from BCG+MMC trial in the BCG-naive setting 👉 Possible signal in higher staged patients 👉 High compliance 👉 Saves BCG in the era of shortage 🤔 Difference between monthly maintenance vs swog 🤔 Effect additive vs synergistic @ANZUPtrials #ANZUP25
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UroToday.com
UroToday.com@urotoday·
Mitomycin + BCG as adjuvant intravesical therapy for high-risk #NMIBC: a randomized phase 3 trial (ANZUP 1301). Presentation by Dickon Hayne, MD, FRCS. #ASCO25 written coverage by @zklaassen_md > bit.ly/3Zaimmv @ASCO
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ANZUP
ANZUP@ANZUPtrials·
Well done! The @ANZUPTrials #BCGMM trial has been presented @ASCO25 showing BCG plus mitomycin a safe & effective alternative to BCG alone & the added benefit of requiring 40% fewer BCG doses. Congrats to Prof Dickon Hayne & team @Prof_IanD @TrialsCentre @MSD_Aus #OmegaPharm
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Jun Gong@jgong15

@ANZUPtrials rand PhIII ANZUP 1301 of intravesical MMC + BCG vs BCG in tx-naive #HR-NMIBC ➡️ no sig diff in DFS, time to recurrence or progression, or OS between arms. Post-hoc suggests MMC addition may benefit in higher-risk (all T1, CIS) subgroup #ASCO25 @OncoAlert

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Ian Davis (Bluesky @profiand)
Ian Davis (Bluesky @profiand)@Prof_IanD·
@UroDocAsh @Merck @IBCG_BladderCA @urotoday @shilpaonc @UrogerliMD @pjhensley11 @WorldBladderCan @BladderCancerUS @ParamMariappan @daviesbj @siadaneshmand Great to hear this. There could be another solution too. Come to the #ASCO25 Kidney and Bladder oral session on Sunday morning shortly before 11am to hear Prof Dickon Hayne present the BCG-Mitomycin @ANZUPtrials ANZUP 1301 #NMIBC outcomes (abstract LBA4504). #BladderCancer #blcsm
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Kevin Keane
Kevin Keane@KevinKeane92·
An insightful evening at the RUM@UWA event with Prof Chris Sweeney sharing expertise on treatment modalities in high-risk prostate cancer. Updates from @ASCO GU 2025 and future directions in mHSPC and localised disease. @uwanews @ChrisSweens1
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