Koch Institute at MIT

A development that could help ensure people are taking their medication on schedule, MIT engineers have designed a pill that can report when it has been swallowed. Giovanni Traverso says. news.mit.edu/2026/pills-com…

Nanoparticles coated with molecular sensors could be used to develop at-home tests for many types of cancer. news.mit.edu/2026/ai-genera…

Research from Patrick Doyle's team offers a new way to deliver antibodies packaged into microparticles that could be injected with a syringe. This could offer patients an alternative to lengthy & uncomfortable infusions: mit-ki.org/4aHnV27

Detecting cancer in the earliest stages could dramatically reduce cancer deaths. To help achieve that goal, @MIT & @Microsoft researchers are using artificial intelligence to design molecular sensors for early detection. @MIT_IMES @kochinstitute @MITEECS news.mit.edu/2026/ai-genera…

@TeresaDavoli3 @nyulangone @khanh_n_dinh @nyugrossman @CancerGrand @columbiacancer @Columbia_Bio @kchenken @MDAndersonNews @RiceCompSci @ColumbiaCompSci @SRsrivatsan @fredhutch @HutchBasicSci @joselmcfaline @ColumbiaBME On January 14 at 2 pm, we welcome @MattG_Jones from @MITBiology and @kochinstitute who will discuss about the quantitative profiling of tumor evolution beyond chromosomes. Register here: cancerdynamics.columbia.edu/events/iicd-se…

A new “dual warhead” therapy from the Hemann, Yilmaz & Lippard labs preserves anthracycline potency while sidestepping efflux pump–driven resistance. The Nature Communications study shows extended survival in metastatic colon cancer models. nature.com/articles/s4146…

Can we demystify endometriosis? On NPR’s Science Fridays (@scifri), Linda Griffith highlights challenges in endometriosis—from ‘squeamishness’ around conversations to difficulties in clinical diagnosis—& promising innovations in modeling & treatment. mit-ki.org/4pRloXq

Happy New Year from the Koch Institute! Wishing our community a year filled with discovery, collaboration, and progress.

MIT Technology Review (@techreview) shines a spotlight on the cutting-edge work taking place in Giovanni Traverso’s lab. From ingestible biosensor pills to capsules that can replace insulin shots, Traverso is focused on improving patients’ lives.   mit-ki.org/3KOLL1u

A new @NatureMaterials study from the Hammond and former Irvine labs shows IL-12 nanoparticles paired w/ checkpoint inhibitors eliminated metastatic ovarian tumors in >80% of mice and formed lasting immune memory. Story: news.mit.edu/2025/new-nanop…

Mini Brains, Major Insights: Robert Langer & Li-Huei Tsai developed “miBrains,” 3D human brain tissue models for disease research and drug testing. Scalable, customizable, and made from donors’ iPSCs, they integrate all major brain cell types. Read more: bit.ly/3rM7iBrains

Out today in @CellCellPress! We studied how environmental stresses like high-fat diets today can prime tumorigenesis months to years in the future (1/n)

Elicio Therapeutics’ Phase 2 trial of its KRAS-targeted cancer vaccine shows promising results: 99% of evaluable pancreatic cancer patients mounted an immune response and 88% responded to their own tumor-specific mutation. investing.com/news/company-n…

As 2025 comes to a close, we’re highlighting some of the year’s standout KI research—from ovarian immunotherapy and CAR-NK cells to antibody-guided chemo, AI-designed nanoparticles, and cancer cell dormancy. More on our website: ki.mit.edu/news/2025/the-…

Thrilled to share the #BBC documentary featuring our technology, #Circulatronics — a new paradigm of #Autonomous, #SurgeryFree #BCI. In “Chris McCausland: Seeing into the Future,” Chris McCausland—an English comedian and actor who lost his eyesight in his early twenties—explores how emerging technologies can profoundly transform human life. The documentary highlights Circulatronics: tiny, sub-cellular-scale, wireless electronics—billion times smaller than a grain of rice—designed to circulate through body fluids, autonomously recognize diseased brain regions, cross blood-brain-barrier and self-implant, eliminating the need for invasive surgery. In this episode, we discuss how Circulatronics could enable: restoration of vision, treatment of devastating neurological diseases, new approaches for terminal brain cancers, and a future where humans could transcend beyond biological limitations! . 🧠 Excerpt of the BBC video: youtube.com/watch?v=GOygvr… 🎬 Full video at BBC iplayer: bbc.co.uk/iplayer/episod… 🎥 MIT Video: youtube.com/watch?v=dDcgLM… 📖 MIT news release: news.mit.edu/2025/new-thera… . . . @MIT @medialab @kochinstitute @mit_nano @mcgovernmit @mitsap #MedTech #Nanoelectronics #Neurotechnology #BCI #DBS #BrainImplant

A team at the @KochInstitute performed cell type–specific immunopeptidome analysis on primary #macrophages and #glioblastoma tumor cells in a coculture system to profile MHC-I–associated antigen presentation at the tumor–macrophage interface. 🔖 @AACR: bit.ly/4oW64YZ

Thank you to Anna Uzonyi (@WeizmannScience) & Lukas Henneberg (@‌MPI_Biochem), the 2024 Amon Award winners, for sharing their groundbreaking research with us. And thanks to our emcees Monica Boselli and Xiaofeng (Allen) Su and Amon Lab alums for your support!

Antibody-lectin chimeras for glyco-immune checkpoint blockade go.nature.com/4aRDpk8

From nematode to Nobel: How an unassuming roundworm has illuminated aspects of biology with major consequences for human health. mcgovern.mit.edu/2025/12/12/cel… @MITBiology @kochinstitute @ScienceMIT @MIT_Picower @hhmi_science @PNASNews

Predicting better lipids: In a cover-winning @NatureBiotech paper, the Anderson & Langer Labs screened 1.6M lipids in silico to speed up successful designs for mRNA delivery to lungs. nature.com/articles/s4158…