Maria Domercq

New paper is out in Brain, Behavior, and Immunity!! 🥳 "P2X4 Drives Sex-Specific neuroprotection in autoimmune neuroinflammation" doi.org/10.1016/j.bbi.… We found that the purinergic receptor P2X4 protects against neuroinflammation, but only in females. Why? 🧵👇

Take a look at our new article! We demonstrate that the Alzheimer´s disease gene Presenilin regulates tau pathology via the autophagy & proteasome pathways. Funded by @CienciaGob @AgEInves @CIBER_ISCIII #CIBERNED @_BrightFocus @INC_UAB link.springer.com/10.1186/s40478…

Today I submitted my review of a manuscript for a journal, which I will not name, and then received the comments sent to authors. There were 7 reviewers!!! Have we lost all sense?

Turkish photographer Uğur Gallenkuş portrays two different worlds within a single image

@FdeCastroS Gracias Fernando!!

@LabDomercq 👏🏻👏🏻👏🏻 Congrats...!

New paper is out in Brain, Behavior, and Immunity!! 🥳 "P2X4 Drives Sex-Specific neuroprotection in autoimmune neuroinflammation" doi.org/10.1016/j.bbi.… We found that the purinergic receptor P2X4 protects against neuroinflammation, but only in females. Why? 🧵👇

@BaleriolaLab Gracias Jimena!!!

@LabDomercq Congrats Maria and cols!!!🥳🥳🥳

Congratulations to @salgado_mata for her excellent work and to all collaborators, particularly @BoueGrabot @upvehu @AchucarroGlia #ARSEP foundation @bioef_

3) This reveals that sex hormones shape neuroinflammatory outcomes through direct modulation of microglial P2X4 function, opening the door to precision, sex-aware therapeutic strategies for MS.

What happens to the brain after focal myelin loss? Our new paper, published today in @Nature tries to answer this question: go.nature.com/3Qgd47r Details in the 🧵 (1/8)

@jposeutrilla @AchucarroGlia No, lo siento.

@LabDomercq @AchucarroGlia Hay transmisión online del simposio? :)

Minisimposium on #ASD: genetics, molecular mechanisms, circuits and behaviour. Organized by @UPV/EHU and @AchucarroGlia. Join us!!! Speakers and details below.

Achucarro Glia School is backed!!! Please check the program. Excellent speakers. Great opportunity to learn on Glia!!! x.com/i/status/20287…

A recent study found that mice with variants in autism-associated genes have difficulty flexibly updating their expectations, providing new insights into the neurobiology of autism: simonsfoundation.org/2025/10/23/map… #neuroscience #BrainAwarenessWeek #BrainWeek

Excited to be back again at Sfari meeting in NY. Excellent meeting, finding colleagues, new ideas, excited findings. Thanks to @SimonsFdn for organising and support

Myelin sheaths persist for weeks following axon degeneration | Science Advances science.org/doi/10.1126/sc…

Registrations and abstract submissions for #AstrocyteCafe2026 are now OPEN!!! Spread the word 🤩 We hope to see many of you on June 3-5 in Pamplona!!! Thanks @KernelScience, for our brand new website and for helping organize this conference! 👇👇👇👇 astrocytecafe.com/#/conference-2…

Stay tuned for the 3rd edition of the Achucarro International Glia School #AIGS2026, organized by @AchucarroGlia and @upvehu at the @pie_upvehu in the magnificent Bay of Plentzia, just minutes from Bilbao. 🧠🔬 Registration opens in March!