Maria Domercq

New paper is out in Brain, Behavior, and Immunity!! 🥳 "P2X4 Drives Sex-Specific neuroprotection in autoimmune neuroinflammation" doi.org/10.1016/j.bbi.… We found that the purinergic receptor P2X4 protects against neuroinflammation, but only in females. Why? 🧵👇

Last day of #FENS2026 Barcelona. One last @AchucarroGlia family photo before we all scatter back to Bilbao. Great conference. Congratulations to the organizers @FENSorg @SENC_

@rosa_paolicelli @NatureNeuro @AnneCompagnion Nice work. Congratulations!!

Our work on #Microglia and #TDP-43 in early #brain development is finally out @NatureNeuro! Congrats to the brilliant @AnneCompagnion and thanks to the many collaborators!!! Enjoy the read!! :) nature.com/articles/s4159…

The shareable link is not working properly, you can access the article here nature.com/articles/s4146…

Excellent opportunity for a PhD working in astrocytes in a top group!! x.com/i/status/20741…

Come and discover our poster at #FENS2026! “PIEZO1 REGULATES MICROGLIAL MOTILITY AND RESPONSES TO EXTRACELLULAR MATRIX REMODELING DURING ZEBRAFISH BRAIN DEVELOPMENT” presented by Irene Tomé Velasco 📌 Poster number: PS01-07AM-113 📅 July 7 🕑 11:30–13:00 Stop by and say hi!

Come and discover our poster today at #FENS2026! “Chemogenetic activation of mature oligodendrocytes reveals a role for myelin plasticity in emotional circuits" presented by Alba Legarda 📌 Poster number: PS02-07PM-467 📅 July 7 🕑 14:00–15:30 Come by and chat with us!

Come today to our talk at #FENS2026! “The Extracellular Matrix as a Key Modulator of Microglia Dynamics”, presented by Federico Soria (@SoriaFN) 📌 Session: S05 - HALL E 📅 July 7 🕑 9:45–10:10 Come and discuss about #ECM and #glia!

FENSGlia – Building the International Glia Community Visit the Network Glia | Joint Booth (158) at #FENS2026 and meet our growing glia network community. Learn about us, connect with colleagues, and enter our raffle! Prizes awarded at the booth (attendance required). #FENSGlia

@TepavcevicVanja @natcomms @oligomoon @Leire18234919 @solerirs @UBB_CIPF @MatuteLab @MatuteC_ @CitlaNex @maaryameliemass @UV_EG @zugazajl Congrats Vanja!!!!

Our article is in press @NatComms! We show that MCT2 regulates oligo metabolism to promote maintenance of myelin and axonal integrity. Kudos to all authors! Co-1st @oligomoon & @Leire18234919, @solerirs @UBB_CIPF @matutelab @maaryameliemas @LabDomercq👇rdcu.be/fqmhQ

📢🧠 New preprint from our group available on @medrxivpreprint. In this longitudinal study in early untreated RRMS patients, circulating M-MDSCs were associated with immune regulatory dynamics and better relapse recovery. Congratulations to all authors! medrxiv.org/content/10.648…

Following Bolaños & Magistretti’s October 2025 review on the neuron–astrocyte metabolic unit, the November 2025 Nature Metabolism review by Asimakidou, Pluchino, Silva and colleagues brings microglia–neuron interactions into the discussion. They are not examining the same cellular mechanism, what connects them is the broader move to place neuronal function within the cellular interactions that shape brain metabolism and brain function. The November review adds the neuroimmune dimension, linking microglial metabolism to cognition, ageing, and disease.

Can't wait for this fantastic Symposium!

Does brain aging always mean vessel loss? 🧠We found a surprising hypervascularization, driving cognitive decline & blood-brain barrier damage in aging. 👇🧵biorxiv.org/content/10.648… Led by @MihailMuc

Take a look at our new article! We demonstrate that the Alzheimer´s disease gene Presenilin regulates tau pathology via the autophagy & proteasome pathways. Funded by @CienciaGob @AgEInves @CIBER_ISCIII #CIBERNED @_BrightFocus @INC_UAB link.springer.com/10.1186/s40478…

Today I submitted my review of a manuscript for a journal, which I will not name, and then received the comments sent to authors. There were 7 reviewers!!! Have we lost all sense?

Turkish photographer Uğur Gallenkuş portrays two different worlds within a single image

@FdeCastroS Gracias Fernando!!

@LabDomercq 👏🏻👏🏻👏🏻 Congrats...!

New paper is out in Brain, Behavior, and Immunity!! 🥳 "P2X4 Drives Sex-Specific neuroprotection in autoimmune neuroinflammation" doi.org/10.1016/j.bbi.… We found that the purinergic receptor P2X4 protects against neuroinflammation, but only in females. Why? 🧵👇

@BaleriolaLab Gracias Jimena!!!

@LabDomercq Congrats Maria and cols!!!🥳🥳🥳