Myklebust Lab

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Myklebust Lab

Myklebust Lab

@LabMyklebust

We're the Lymphoma Biology Group at Radiumhospitalet, Oslo University Hospital.

Oslo, Norway Katılım Nisan 2019
436 Takip Edilen444 Takipçiler
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Ash Alizadeh, MD/PhD 🇺🇸
Ash Alizadeh, MD/PhD 🇺🇸@AshAlizadeh·
Honored to share our newly published manuscript ascopubs.org/journal/jco which demonstrates that circulating tumor DNA (ctDNA) by PhasED-Seq offers the most precise definition of remission after frontline therapy for patients with large B-cell lymphoma (LBCL) out now in @JCO_ASCO. #ctDNA detection of #MRD. 1/18
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Chloé Steen, PhD
Chloé Steen, PhD@ChloeBSteen·
I'm hiring a postdoc in computational biology! Come work in beautiful Oslo, Norway, and enjoy free universal healthcare, affordable and high-quality daycares, an attractive pension scheme, and many other benefits, while doing exciting impactful science! 2411.webcruiter.no/Main2/Recruit/…
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Rahul Satija
Rahul Satija@satijalab·
Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25
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Stephanie Hicks, PhD
Stephanie Hicks, PhD@stephaniehicks·
Friends, I am at a loss of words for how devastating it would be to lose the entire intramural #NIH program. Some of the biggest medical and scientific breakthroughs have come from scientists in the NIH Intramural program. #SaveTheNIH science.org/content/articl…
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Cancer Cell
Cancer Cell@Cancer_Cell·
Online Now: The hallmarks of cancer immune evasion dlvr.it/TFFy1H
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MalmbergLab
MalmbergLab@MalmbergLab·
Very important and much needed funding to establish ATMP Norway, a multi-nodal national infrastructure for cell and gene therapy. Building on investments in GMP laboratories at @Oslounivsykehus and Haukeland University Hospital and a partnership with @UniOslo_MED.
Oslounivsykehus@Oslounivsykehus

Vi er svært glade for tildelingene fra @forskningsradet i dag, som bla. gir midler til å forsette å jobber med celle-genterapi, samt til forprosjekt for protonterapi. 1,3 milliardar kroner til forskingsinfrastruktur (forskningsradet.no)

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Kjetil Tasken
Kjetil Tasken@KjetilTasken·
Norwegian Cancer Symposium, Sept 9-10, 2024, celebrating 70 years of #CancerResearch at Institute for Cancer Research, @Oslounivsykehus, starts with >430 participants, speakers & invited guests. Look forward to talks by 15 invited speakers, 8 short talk speakers, and 118 posters.
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Selma Sorri
Selma Sorri@spsorri·
Super glad to have been a part of this project!🪩 Check out the highlights of our study and play with the data at leppalab.shinyapps.io/KLHL6
Leo Meriranta@Merijellona

Friends! I am super-excited to share our story on KLHL6 in this @BCD_aacr 📣KLHL6 targets the B-cell receptor and lymphoma mutations perturb this homeostasis! 🔓Read doi.org/10.1158/2643-3… 🪩Joint editorial in @CD_AACR doi.org/10.1158/2159-8… 🧵Let’s go

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Ivana Spasevska
Ivana Spasevska@ivana_spasevska·
It's been a great pleasure to attend #ECI2024 in Dublin and an honor to present our research on cytotoxic CD4 T cells in B cell lymphoma. Fantastic meeting filled with many inspiring talks and virbrant discussions. @LabMyklebust @CoE_PRIMA @NSImmun
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Jillian Wise
Jillian Wise@the_wiselab·
🔍 The study underscores the importance of early and stable genetic alterations in guiding treatment strategies. As we uncover more about FL’s genomic landscape, we move closer to better prognostic tools and therapeutic options. #CancerTreatment #Genomics
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Jillian Wise
Jillian Wise@the_wiselab·
🧩 Gains in chromosomes 12, 18 (TCF4), and loss in 6q were identified as stable copy number alterations, with a newly developed tool for screening longitudinal biopsies. These early events could be key for future diagnostic and monitoring strategies. #LymphomaResearch
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Jillian Wise
Jillian Wise@the_wiselab·
💡 One intriguing discovery: Tumors with EZH2 mutations showed reduced expression of several histone genes, suggesting a unique epigenetic dysregulation in FL. This could open new avenues for targeted therapies. #Epigenetics #Oncology
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Jillian Wise
Jillian Wise@the_wiselab·
🧬 The study analyzed 94 longitudinal biopsies from 44 FL patients using multi-omics techniques. Key findings? Complex patterns of clonal evolution were observed, yet recurrent mutations in genes like CREBBP and KMT2D occur early. #Genomics #CancerResearch
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Myklebust Lab
Myklebust Lab@LabMyklebust·
We also discovered that cases with EZH2 mutations had downregulation of histone linker genes, potentially contributing to epigenetic deregulation in FL.
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Keşfet

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