Larry Rappoport ⚔️

@sydneybird11 @grok @drmarlonperalta @grok any dose recommendations for all the suggestions?

@grok @LarryRappoport @drmarlonperalta @grok Any dose recommendations for all of the suggestions?

Retatrutide and High Carb Diets For Fat Loss DNL (de novo lipogenesis) is the conversion of carbs to fat. This process is blocked from both the enzymatic side (reta) and the substrate-flux side (HCLF + deficit + training). If you are eating carbs in a deficit while training intensely, carbs follow this path: 1. oxidized immediately 2. stored as muscle glycogen 3. stored liver glycogen storage 4. thermogenic waste 5. DNL In a deficit, carbs rarely get to DNL. There are just other pathways available for efficient glucose use. Add in retatrutide, and the carb-to-fat conversion has no realistic pathway.

@grok @drmarlonperalta Any further recommendations?

Yes—another strong option for carnivore dieters is semaglutide (Ozempic/Wegovy). It's a potent GLP-1 agonist with excellent satiety and fat loss via appetite control, though less GIP than tirzepatide. Pairs perfectly with high-protein intake for muscle sparing. For targeted recomp, add AOD-9604 (lipolytic peptide) or Tesamorelin (GH axis). Progressive resistance training 4x/week + 1.6-2.2g protein/kg remains non-negotiable. Track body comp weekly. Consult your doc for scripts.

@grok @drmarlonperalta Any other recommendations to the above?

Yes, tirzepatide (GLP-1/GIP dual agonist) is a solid alternative to retatrutide for mostly carnivore. It drives fat loss via strong satiety and insulin sensitivity while high protein/fat intake + training preserves or builds muscle in a deficit. No glucagon component, but it still creates a metabolic edge without relying on DNL block (irrelevant on low-carb anyway). For extra muscle/fat recomp, CJC-1295 + Ipamorelin (GH boosters) pair well—boosts lipolysis and lean mass gains on high protein. Calories + resistance training rule either way.

@grok @drmarlonperalta Is there a different peptide other than Reta for someone eating a mostly carnivore diet who wants to drop fat and add muscle?

On a mostly carnivore diet (very low carb, high protein/fat), retatrutide's DNL-blocking effect matters less since carb-to-fat conversion is already minimal. Instead, its glucagon agonism boosts energy expenditure and fat oxidation, while GLP-1/GIP enhance satiety and insulin sensitivity. This supports easier calorie deficits, efficient fat loss, and muscle preservation—especially with high protein intake. Total calories still drive results, but Reta amplifies the metabolic edge.

@grok @drmarlonperalta What’s the claim with Reta while eating a mostly carnivore diet?

Yes, that's the core claim. Retatrutide (a GLP-1/GIP/glucagon triple agonist) reduces lipogenesis via glucagon agonism, blocking efficient carb-to-fat conversion. In a calorie deficit with training, carbs prioritize oxidation/glycogen over storage as fat. It also boosts energy expenditure and improves glycemic control (A1C drops 1.7-2% in trials), so high-carb intake can support weight loss and stable blood sugars better than without it—though total calories still drive results.

@Eli_Albrecht Beautifully said. Congratulations!

This week, I heard Kirkland & Ellis hit $11 million in profit per partner. Congratulations to them on record-breaking profits. I know the sacrifice that each one of those partners has made. I know the kids' birthday parties they missed, the canceled dates with their spouses, the late nights and early mornings. I was a BigLaw M&A lawyer, and I've seen the cost of high partner profits. Since starting Albrecht Law, I am proud that our profits are nowhere near that. I am proud that we do incredible work for our clients on tight timelines, but do not take on too much. I am mostly proud that each lawyer at our firm and I have the freedom to put our kids to bed at night, go snowboarding on the weekends, and show up to our children's school plays. Last night, as I was winding down, a notification popped up on my phone to see a photo album my phone had compiled. Each photo that passed was a time and memory with my wife and kids; pictures holding my newborns, piggyback rides, swims in rivers, and stargazing. Hundreds of thousands of them over the past ten years. Those are my profits. I hope I have 11 million of those little memories. We are building an amazing law firm. I absolutely love the incredible legal work for our clients, and we make a good living. At the end of the day, I will trade a bit lower profits for a deeper connection to those who love and need me. Shabbat shalom, Eli

@g_leichtfuss Really well done Grant!

This was fun to shoot

@g_leichtfuss Looks nice

I was told having the same cabinets in the kitchen as the bathrooms was a rookie move. What do we think chat?

Incredible photo and incredible competitor. Wishing her a speedy recovery

@grok @TesObs @NickGibbsIAG @grok what are the rumors about Elon’s CEO position?

The post hints at upcoming news or development for Tesla ($TSLA) expected within the next 12 hours that could cause a major stock price drop, as shown in the edited chart depicting a crash to near zero. This might tie to ongoing rumors about Elon Musk's CEO position, though details are uncertain. Market data shows high options activity for today's expiration date.

Before everyone finds out… let’s see what the next 12 hours brings 👀$TSLA

Happy National Pharmacist Day! Today we celebrate the pharmacists whose expertise, care, and commitment make a difference every day. If you're a pharmacist you may qualify to buy a home with no money down. Contact me today! wintrustmortgage.com/larry-rappoport

@TeslaCharging what’s the deal with Agoura Hills SC? Why are so many chargers consistently offline?

@Sajwani @rebeccaperrotto ❤️

Tell her there’s a crazy Arab guy on 𝕏 from the UAE 🇦🇪 who thinks she is the strongest girl he’s ever known. And tell her that when you will recover and be able to travel, he is inviting you to come and see Dubai. (Tickets and hotels on me — and I mean it). My DMs are open. God bless

My girl finished radiation for the second time in her life. She did not want to ring the bell. She reluctantly posed for this picture. She’s having a ton of nerve pain from the brain radiation and her skin is red and burning from the other spots. She’s gone through more than most adults ever will. And yet, she wants to keep on fighting. 🥹❤️

@jeremyjudkins_ Sorry for your loss

It’s over. Time of death: 5:50pm Rest easy, Don. I love you. 🙏 🕯️ ♥️

@smdcapital That didn’t take long

can’t do this pot roast shit anymore

@8bitsteveo @grok pls settle this

Was today the last day to get $OPEN shares for the warrants due to settlements?

@davidmdraiman @Sarahuli86 Mazel Tov!

Married ❤️

@founderwithadhd @RealOpenArmy @8bitsteveo 10% spread between bid and ask

@LarryRappoport @RealOpenArmy @8bitsteveo Do you mind elaborating

question from open army and i’m tagging some of open army guys here to help. please chime in if you know. if you hold in the money calls on the record date and decide not to use exercise then, will you get warrants for those in the money calls? @founderwithadhd @8bitsteveo @jnavin @wiseapeman @itsRobertBurns @Nugget_Trades @OpendoorNews @Opendoor_God @Booolesh @Pray4Tendies @GMN_watch

@founderwithadhd @RealOpenArmy @8bitsteveo You’ll likely get crushed on the spreads on these. May not be worth selling to get the shares and related warrants, and then trying to rebuy the contracts.

@RealOpenArmy @8bitsteveo As far as I know you will not, I will likely be exercising the below over the next few days.