Laura Meems

1.4K posts

Laura Meems

Laura Meems

@LauraMeems

MD PhD🇳🇱|👩‍⚕️Cardiology| 👩‍🏫 Postdoc Fellow in Translational Cardiology focusing on Sex differences in Heart Failure, HFpEF + Cardio-Obesity. Glutenfree.

Groningen, the Netherlands Katılım Ocak 2009
211 Takip Edilen444 Takipçiler
Laura Meems
Laura Meems@LauraMeems·
@DrDamluji @NEJM @AHAScience Wonderful summary of a very important trial. I believe inverting modification will represent a novel treatment pillar in HF(pEF)! One of the main questions to be answered: will we use it as chronic therapy (such as traditional HF drugs) or as burst therapy (such as diuretics)?!
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Laura Meems
Laura Meems@LauraMeems·
Today I gave a talk at #ESC2024 about #glp1ra in #HFpEF. A fully packed room and 12 minutes to talk about new insights. What you missed? ✅ obesity is important, also for cardiologists ✅ glp1RAs are cardioprotective ✅ MoA studies are needed @escardio @HFA_President
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Laura Meems
Laura Meems@LauraMeems·
@matthewmylee Great work Matt!! Also very important to differentiate the effects of semaglutide. Will be important how to position this drug and decide who to prescribe and it’s duration (although studies suggest that even short time therapy may have long-term benefits on atherosclerosis!)
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Laura Meems
Laura Meems@LauraMeems·
@MaartenVHemelen @VerwerftJan Very relevant question since cardio-obesity is a real problem! In our clinical practice, we start with a general work-up with NTproBNP, ECG and echocardiography. Next CPET or iCPET can be performed to assess intracradiac pressures. Not sure? Discuss with HFpEF expert center!
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Maarten Van Hemelen
Maarten Van Hemelen@MaartenVHemelen·
@VerwerftJan What would you say is the best way to screen for this? In general internist practice it's quite common to see obese patients with poor exercise tolerance and a lot of edema. Often difficult to distinguish venous from cardiac disease, even after cardiology review.
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Henry Han
Henry Han@HanCardiomd·
"Deciding on mechanical support in cardiogenic shock: 📍Use: Yes, early intervention. 📍Device choice: IABP, mLVAD, or ECMO based on clinician preference and availability. 📍ECMO criteria: Inadequate response to IABP/mLVAD, preferentially in younger, non-obese patients. 📍ECMO setup: Consider ECMO alone or with unloading strategies, prioritizing ABP over IMPELLA. #CardiogenicShock #HeartFailure2024 @escardio @HFA_President
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Henry Han
Henry Han@HanCardiomd·
Epidemiology, outcomes and classifications of CS 📍CS comprises 3-5% of AHF cases. 📍AMI was main cause, but recent data shifted landscape. 📍CS is the most severe form with high mortality. 📍In-hospital mortality: 30-40%, half within 24h. 📍30% day-mortality: 45-50% in registries & RCTs. 📍First 2 months post-discharge: highest vulnerability. #CardiogenicShock #HeartFailure2024 @escardio @ESC_Journals @ShelleyZieroth @MarcoMetra @AndrewJSauer @RyanTedfordMD @mewton_nathan
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Laura Meems
Laura Meems@LauraMeems·
@VerwerftJan @TaubenA @hvanspall Very interesting study! Was there a difference in HF subtypes (makes more HFrEF, females more HFpEF?) that could explain the observed differences?
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Tauben Averbuch MD
Tauben Averbuch MD@TaubenA·
Incredibly grateful to @hvanspall to present #PACTHF 5yr update at #HeartFailure2024 🔑 findings: 🔴 5 year ☠ = 65% in ♂️ and ♀️ patients 🔴 💲were high, and driven by readmission 🔴 🚫 sex differences in outcomes/costs, but ⬆️ specialist care in ♂️, ⬆️ supportive care in ♀️
Novi Yanti Sari@slumberbell

How do gender differences impact clinical outcomes and healthcare resource use after #HF hospitalization? #PACTHF registries #LBCT: 📍 64% mortality, 🧔‍♂️=👩‍🦳 📍 Higher costs for 🧔‍♂️ in specialist and invasive care; more home & long-term care for 👩‍🦳 #HeartFailure2024 @hvanspall

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Laura Meems
Laura Meems@LauraMeems·
@salonfahigsujet Wat fijn dat de publiekslezing je meer informatie heeft gebracht! In NL zijn een paar ziekenhuizen zeer actief in opsporen en behandelen van onzichtbaar #hartfalen (#HFpEF). Naast @umcg ook Maastricht en A’dam (VU). Toch is er nog veel werk te doen, dus wij strijden door!
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Volbloedidioom
Volbloedidioom@salonfahigsujet·
@LauraMeems Goedenavond Laura, Deze 'wildvreemde' stuit bij enig toeval op jouw profiel. De publiekslezing (YouTube) van dr. Westenbrink en jou vond ik erg interessant. Zijn er landelijk méér academische ziekenhuizen actief die deze 'vorm' onderzoeken c.q. behandelen?
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Laura Meems
Laura Meems@LauraMeems·
Ben jij… ✅ een (bijna) arts met ambitie onzichtbaar hartfalen gemakkelijker op te sporen ✅ geïnteresseerd in de nieuwste MRI technieken en cardiologie ✅ een zelfstandige teamspeler die niet bang is om te innoveren Solliciteer dan nu! #phdstudent werkenbijumcg.nl/-/vacatures/ar…
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Laura Meems retweetledi
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Maja Cikes
Maja Cikes@MajaCikes·
#PCHF Zürich continues to set standards and lead #HeartFailure education in Europe, with a global reach. Congratulations to all of the graduates, faculty and leadership of the course - 5 generations raised, more to come! Honored to be part of this stellar family! 🎓💥🫀📚
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Laura Meems
Laura Meems@LauraMeems·
Thank you prof. Marc Pfeffer for your words of wisdom: “Be part of something, you cannot do it by yourself!” And that’s exactly what #PCHF has been: a 2 years course, and a life-long friendship with likeminded HFenthusiasts! #heartfailure #graduation @CardioZurich @escardio
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Laura Meems
Laura Meems@LauraMeems·
PCHF module 8: the final module! Looking forward to learn from the giants one more time. Fun, heart failure facts and a final graduation ceremony on Saturday. Let’s get started! @CardioZurich @drsoli4030 @mjschuuring @BarandiaranHF
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Eric Topol
Eric Topol@EricTopol·
Just published @NatureMedicine Randomized trial of tirzepatide (Mounjaro) vs placebo *after* 12 weeks of intensive lifestyle intervention and >5% weight loss nature.com/articles/s4159… At 72 weeks, Placebo group gained 2.5% weight back; GLP-1 drug lost additional 18.4% body weight
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Laura Meems
Laura Meems@LauraMeems·
@peripheryk18191 @FZores Great question! NYHA I patiënt so I wouldn’t add anything. Worsening HF signs and complaints? Add SGLT2i in euvolemic patients and diuretics followed by MRA in volume overloaded pts.. Main question remains: WHY #heartfailure? Etiology is key 🔑 @AndreasGevaert @HanCardiomd
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peripheryk
peripheryk@peripheryk18191·
53 yo patient with ischemic cardiomyopathy, initial LVEF 40 %, now 50 %, NYHA class 1 and strictly normal natriuretic peptides while on ACEi and betablockers. Referred for HF meds uptitration. Would you prescribe MRA &/or iSGLT2 ? Why ? #CardioTwitter @FZores
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Laura Meems
Laura Meems@LauraMeems·
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