Lily Huang
103 posts
Lily Huang
@LilyHuangLab
Associate Professor at UT Southwestern Medical Center
Katılım Aralık 2019
178 Takip Edilen96 Takipçiler
Excited to share our new study published online today @CD_AACR. Beyond mutagenesis, we show that LINE-1 locus-specific transcription reshapes 3D genome architecture to control cancer gene expression @JianXuLab @StJudeResearch
aacrjournals.org/cancerdiscover…
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Why did the first CRISPR gene therapy work so well in treating SCD and β-thalassemias? Our latest study provides the answer - CRISPR editing silences BCL11A through disruption of epigenetic insulation. doi.org/10.1182/blood.…
@JianXuLab @StJudeResearch @yuefeng_1 @NorthwesternU
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Humble to receive the John Goldman Fellowship from Leukaemia UK to support our work to find gentler and more targeted therapies for acute lymphoblastic leukaemia. @EdinUniMedicine
Leukaemia UK@LeukUK
📢 We’re funding two new groundbreaking studies, each aimed at developing kinder, more effective treatments for acute lymphoblastic leukaemia (ALL). Meet Dr @StefanoComazze1 from the Uni of Edinburgh - one of our two new John Goldman Fellows for 2025. leukaemiauk.org.uk/research-and-a…
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@emerybresnick Very interesting story! Congrats Emery and team!
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GATA2 decommissioning of enhancers: A mechanism to constrain inflammatory signaling: Cell Reports cell.com/cell-reports/f…
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Thrilled to announce my official promotion to associate professor with tenure at UTSW! So grateful to all the trainees in the lab for their hard work and proud of their accomplishments over the last several years. This an individual recognition but truly a team effort!
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Lily Huang retweetledi
📢The Department of Cell Biology is hiring! We have two tenure track faculty positions open. See below for more information and how to apply.
🧫🧪🔬
jobs.utsouthwestern.edu/job/22292356/a…
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Thankful for the opportunity to present our work using #BEAT #AMLsm @LLSusa @FiekeHoff @NIH @UTSWMedCenter @utswcancer - Not all RAS mutations are created equal! @BloodAdvances
DAVA Oncology@DAVAOnc
Optimizing AML risk in older adults: @madanatyazan @UTSWcancer present the 2024 Beat-AML ELN-refined model—combining 2022 ELN and mutation score—to better predict survival in ≥60 yrs on lower-intensity therapy #DAVAHeme #BloodCancer
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Delighted to share our recently published work on the role of DDX41 in resolving G-quadruplexes to maintain erythroid genome integrity and prevent cGAS-mediated cell death. rdcu.be/ezlGS @NatureComms
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We report the first physiological benefit of ascorbate/vitamin C deficiency: protection from a major human parasite which needs it for development. We propose that this can explain why ascorbate became a vitamin (its synthesis was lost) in humans and many other animals.
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Thrilled to share our new @NatureCellBio paper, led by our amazing student @DohunKim96: Mitochondrial NADPH powers mitochondrial fatty acid synthesis to sustain lipoylation, mitochondrial translation, and oxidative metabolism. rdcu.be/eiyH7
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Looking for some reading in the New Year? Our latest paper showing that HGF can create connection between epithelial tubules in vitro and in vivo. @CellUtsw @UTSWNephrology
pnas.org/doi/10.1073/pn…
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Gene therapy is transforming how we treat genetic disorders, but what if mutations in more than 30 genes can cause similar symptoms?
Now published in @CellStemCell (cell.com/cell-stem-cell…), we report the development of a universal gene therapy for Diamond Blackfan anemia.
1/n
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Congrats Julia Phan + Aslan Tasdogan for their paper in Science today: hematopoietic stem cells (HSCs) & erythropoiesis get activated during pregnancy and after bleeding by retrotransposons that turn on in HSCs activating cGAS/STING & interferon signaling
science.org/doi/10.1126/sc…
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Congrats Stefano on a very unexpected result: elimination of ascorbate from multipotent hematopoietic progenitors is sufficient to confer long-term reconstituting potential in irradiated mice. Ascorbate suppresses leukemia partly by negatively regulating self-renewal potential.
Children’s Research Institute at UT Southwestern@CRI_UTSW
ONLINE NOW, New research from @StefanoComazze1 & @SJMorrison_ out in @BloodJournal: Ascorbate (vitamin C) deficiency increases quiescence and self-renewal in hematopoietic #stemcells and multipotent progenitors. Read it ⬇️ ashpublications.org/blood/article/… #relentlessdiscovery
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Postdoc opportunity! We are recruiting a postdoc to study hematopoiesis and blood cancers. Learn more and apply: labs.utsouthwestern.edu/huang-lily-lab
#Postdocs #Postdocposition #Postdocjobs #Academicjobs #researchjobs
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Thank you so much to UTSW PDA for this honor. This award truly belongs to my lab – I’ve been fortunate to be surrounded by such talented and incredible people.
UTSWPostdocOffice@UTSWPostdocs
Congratulations to @Sorrell_Lab on being nominated for and selected as the winner of the Excellence in Postdoctoral Mentoring Award! The @utswpda #postdocs look forward to your talk tomorrow on 'Building your own toolbox' #NPAW2024
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Very proud that our discovery that phophoserine RUNX1 promoted megakaryocyte (MK) fate specification in primary human MEP is out!
@YaleCCEH @Yale_LabMed Work of many including the amazing @NKwonHem
sciencedirect.com/science/articl…
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@madanatyazan @FiekeHoff @BloodAdvances @utswcancer @UTSWInternalMed @UTSWIMchief Congrats Yazan and team!
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Congratulations @FiekeHoff on this publication in @BloodAdvances 👏👏Check out our novel genomic risk score to refine prognosis for older adults with AML receiving lower-intensity therapy! Clinically relevant practical prognostic tool! @utswcancer @UTSWInternalMed @UTSWIMchief
Fieke Hoff@FiekeHoff
Excited to share our publication in @BloodAdvances emphasizing the need for a refined risk stratification model for older patients with AML receiving lower-intensity treatment. A great collaboration with @LLSusa! doi.org/10.1182/blooda… @madanatyazan
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@RichardVoit @UTSW_PedsHemOnc @CRI_UTSW @utswcancer Welcome to UTSW Richard! Looking forward to more discussions and interactions with your laboratory!
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Next month the Voit lab will open @UTSW_PedsHemOnc @CRI_UTSW @utswcancer continuing our work studying transcriptional dysregulation in pediatric bone marrow failure and leukemia. Looking to hire at all levels, yes even level 10.
Website and official job posting coming soon.
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