MarioniLab

Are you missing cells and cell types in your single-cell multiome experiments @10xGenomics? Check out EmptyDropsMultiome @MarioniLab

Join our faculty: ebi.ac.uk/research/groups - our 9-year tenure nurtures our group leaders to go on to do great things: @VirginieUhlmann @MoritzGerstung @OliverStegle @MarioniLab @teichlab @pedrobeltrao

Mark you calendars! Next Cambridge Computational Oncology Meeting is May 5 at the EBI in Hinxton. Speakers: Hillary Elrick @hbelrick , Alex Gutteridge @ruggedtextile and Peter Campbell

Happy to present my recent work - a cluster-free method for DE testing, leveraging overlapping neighbourhoods in the graph representation of sc-data (aka miloDE): biorxiv.org/content/10.110… . A little thread below describes the motivation and suggestions on interpreting the results.

The developing human lung has been mapped in unprecedented detail, identifying 144 cell states in the early stages of life, and uncovering new links between developmental cells and lung cancer. ebi.ac.uk/about/news/res…

Excited to share @CarineStapel and my #singlecell #singleorganoid time course of #gastruloid development. We reveal substantial inter-organoid heterogeneity, and show why understanding it is critical in #organoid #perturbation experiments. A #tweetorial (1/18)

AlphaFold DB will boldly go where no scientist has gone before. With over 200 million protein structure predictions added to the database, AlphaFold DB now gives users open access to a 3D protein universe. #AlphaFold @DeepMind ebi.ac.uk/about/news/tec…

A magical week at the Marioni Lab retreat - a blessing of (purple) unicorns indeed and many (uni)corny jokes

John Marioni has been elected as a new Fellow to the @acmedsci 👏 in recognition of his remarkable contributions to biomedical science and the generation of new knowledge to improve the health of people everywhere. #AMSFellows2022

We're hiring! Looking for an enthuastic postdoc to join the team and work with single-cell genomics data to construct and compare senescence trajectories for cells. Deadline 22nd Feb embl.org/jobs/position/…

The new @EMBL Programme has launched! We're proud to be a part of @EMBL and we're looking forward to contributing our #bioinformatics expertise to this exciting new scientific programme that ushers in a new era in the life sciences.

Congratulations to @Blavatnikawards 🇬🇧 Finalist 🏅 Finalist in Life Sciences Dr. John Marioni @MarioniLab @emblebi @CRUK_CI #Blavatnik2021 bit.nyas.org/3n0x0Yb #computationalbiology #RNAtranscription

What are the ripples of making data #openaccess? A recent independent report quantified these efforts to explore the role of #opendata in the life sciences today. #OAweek #opendata ebi.ac.uk/about/our-impa…

Differential abundance testing on single-cell data using k-nearest neighbor graphs go.nature.com/2Y69iSH

Still time to apply for our new postdoc position using computational approaches to study developmental trajectories across species. Deadline 19th September jobs.cam.ac.uk/job/31028/

NEW POST: We (virtually) sat down with John Marioni, new collaborator on the Cancer Grand Challenges IMAXT programme @emblebi @CRUK_CI @sangerinstitute to find out more about his work and what excites him about the project. Read more - bit.ly/3svUnMP

We're looking for a new postdoc in the Marioni group - a two year position to work on developmental trajectories across species using single-cell approaches and data integration methods jobs.cam.ac.uk/job/31028/

Congratulations to Alsu @Alsu_Troost! Fantastic work.

Fantastic to see @RArgelaguet and the team's work featured in this great @Nature article on the computational challenges of single cell multiomics! nature.com/articles/d4158…

Congratulations to our very own John Marioni and @Alexbateman1 and @embl’s Takashi Hiiragi for being elected as new @EMBO Members. 🎉 #EMBO #ScienceAward @MarioniLab ebi.ac.uk/about/news/ann…