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Mathi Thiruppathy
193 posts


@labonnelab Thanks so much Carole! Glad you enjoyed it! 😃
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Super exciting and beautiful new work from the talented @MathiThiru95 nature.com/articles/s4158…
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Really appreciated this opportunity from @the_Node to write about the amazing journey I got to be on for 6 years and the people I met on the way.
Every day I feel fortunate to live in and work for a society that chooses to be curious. I hope it continues to do so. ✨
the Node@the_Node
Fish, Frogs, Friends, Lend me your Ears. 🐟🐸🐁🦎 Read this 'Behind the paper' story from @MathiThiru95 about her PhD work with @CrumpLab: thenode.biologists.com/fish-frogs-fri… #DevBio #EvoDevo
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Mathi Thiruppathy retweetledi

Here is the 2025 embryo alphabet from alligator to zebrafish. Developmental biology is stunning & leads to important discoveries for human medicine. @SocDevBio @NIH @NSF

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Nice article in Scientific American about our work on outer ear evolution and a complimentary study from the lab of Maksim Plikus on role of unique lipids in mammalian ear cartilage. @MathiThiru95 @USCStemCell @KECKSchool_USC
scientificamerican.com/article/our-ea…
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Mathi Thiruppathy retweetledi

Sox10 is required for systemic initiation of bone mineralization
Read this Research Article by Stefani Gjorcheska, Lindsey Barske and colleagues @CincyResearch:
journals.biologists.com/dev/article/15…

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Excited to share our new publication, “Bidirectional histone monoaminylation dynamics regulate neural rhythmicity;” a massive collaboration across 5 labs (@Yael_David__ @MuirLab @SimoneSidoli and Haitao Li) See 🧵 below for the highlights nature.com/articles/s4158…
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Mathi Thiruppathy retweetledi

You can view the PDF of our gills to outer ears paper here: rdcu.be/d5Ml5
Also the link to the article on Nature is now working again: nature.com/articles/s4158…
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Mathi Thiruppathy retweetledi

Welcome to embryo alphabet. Each day I will post an unannotated embryo image. Today E is for elephant. Repost tweet w/an image of a different species embryo & add a quote including name that begins with same letter of the day. @SocDevBio

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Thanks especially to @CrumpLab for providing the opportunity to do exciting, diverse experiments, as well as the necessary guidance and confidence!
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Thank you to all co-authors! @GillisLab @EvseenkoLab @YaWenChenMSSM @goodfrognosis and everyone not on Twitter/X. It's hard to emphasize how amazing it's been to work with people of such diverse expertise who still had an interest in various obscure aspects of this work.
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Excited to share this story from my PhD revealing the surprising legacy of our gill-bearing ancestry in the form of our cartilaginous outer ears, summarized in this series of Tweets.
Crump Lab@CrumpLab
The outer ear is a mammalian innovation but where did it come from? In our study in @Nature, @MathiThiru95 and colleagues find that the outer ear arose from modification of an ancestral gill program first originating in marine invertebrates. nature.com/articles/s4158… 1/n
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Mathi Thiruppathy retweetledi

An @USCStemCell study published in @PNASnews has identified gene regulators that enable fish and lizards to naturally regenerate their hearing. The findings could guide future efforts to regenerate hearing for patients. @CrumpLab @KeckSchool_USC stemcell.keck.usc.edu/study-breaks-t…

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Mathi Thiruppathy retweetledi

🎉 We're excited to share our new research in @Nature! We reveal that crocodile head scales self-organize through compressive folding of the skin - a mechanical twist on their development & evolution!
Please read & share 🐊🔬 @genevunige @UNIGEnews
nature.com/articles/s4158…
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Mathi Thiruppathy retweetledi

Nature research paper: Adipose tissue retains an epigenetic memory of obesity after weight loss go.nature.com/4eJizC8
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Mathi Thiruppathy retweetledi

Embryology: Concepts and Techniques in Modern Developmental Biology 🧫 🧬 🔬 🦠
June 1 – July 15, 2025
Deadline: January 22, 2025
go.mbl.edu/embryology

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I am excited to announce that our @ClouthierLab @NicholsLab work describing the role of the Gq/11 signaling pathway in lower jaw development is now out on Biorxiv! biorxiv.org/content/10.110…
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Mathi Thiruppathy retweetledi

Do you love evo-devo and want to do a PhD on millipede trachea homology in beautiful Vancouver 🇨🇦?
Come join my lab! form.jotform.com/242534537864262
Please re-tweet :)



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Mathi Thiruppathy retweetledi

Our paper ‘Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis’ is now on biorxiv! We introduce weMERFISH, a platform for profiling gene expression in entire embryos at subcellular resolution. Here is🧵biorxiv.org/content/10.110… (1/12)
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Excited to start my postdoc in @kamberovlab at UPenn studying the development and evolution of eccrine sweat glands and human thermoregulation. Thanks to all my new lab mates for the warm welcome. 😃
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@BenjaminWeekley @kamberovlab Thanks Ben! Can't wait to meet up some time when I'm in New York. :)
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@MathiThiru95 @kamberovlab Congrats Mathi!!! And welcome to the east coast!!
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