Matthias_Winkle

@SigmaAldrich @annasmyers_ Chocolate!

It’s World Chocolate Day, and we’re excited to announce that we’re giving away our famous Sigma-Aldrich chocolate bottles!

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Interested in becoming part of the next generation of drug developers? Would you like to pursue a PhD? 🎓 We are hiring! Check out our 11 open positions across Europe 🌍👇 @deDuveInstitute @JFCLab @UCLouvain @IBS_Grenoble @LaStatale @UL_FFA @MartinLab_ICIQ @amsterdamumc @IMBatUQ

Just me and a 30 m E. coli in Edinburgh

We are proud to share the latest @train2target paper from our #ESR Federico Corona In this paper, the authors explore the crosstalk between #OMP biogenesis and #peptidoglycan maturation Congratulations to al the authors!! Vollmer lab @KleanthousLab nature.com/articles/s4158…

👇👇 Very happy to be on board on this fantastic story about the role of PG on the spatiotemporal organisation of OMPs! Special congrats to the first authors Gideon Mamou (from @KleanthousLab) and Federico Corona (Vollmer lab)! nature.com/articles/s4158…

Peptidoglycan maturation controls spatiotemporal organisation of outer membrane proteins in Escherichia coli biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Mechanisms of action of antibacterial agents and of antibacterial resistance go.nature.com/2VCzy5i

The amidase DpaA can detach outer membrane-anchored Braun’s lipoprotein from peptidoglycan. This detachment is important under some stress conditions. @mBioJournal skyw.io/NTB9fQ

Very happy to announce this publication by @AranchaLopezPe1 and colleagues in @antibioticsmdpi Discovery of Pyrrolidine-2,3-diones as Novel Inhibitors of P. aeruginosa PBP3. doi.org/10.3390/antibi…

@Train2Target Why do I look like a giant?!

That was it! We had a good time in Grenoble and are all going back to our homes-away-from-home! Here's the group pictures :)

We're very happy to announce that this work on DpaA by @MatthiasWinkle and colleagues has been published in MBio. DpaA Detaches Braun’s Lipoprotein from Peptidoglycan Congratulations to the authors! mbio.asm.org/content/12/3/e…

DpaA Detaches Braun's Lipoprotein from Peptidoglycan dlvr.it/Rz5nWx

New paper by @Train2Target Elisa Consoli @TannekedenBlaau and @JFClab The Escherichia coli Outer Membrane β‐Barrel Assembly Machinery (BAM) Anchors the Peptidoglycan Layer by Spanning It with all Subunits Congratulations to the authors! doi.org/10.3390/ijms22…

Recently accepted: ActS activates peptidoglycan amidases during outer membrane stress in Escherichia coli onlinelibrary.wiley.com/doi/10.1111/mm…

Recently accepted: The active repertoire of Escherichia coli peptidoglycan amidases varies with physiochemical environment onlinelibrary.wiley.com/doi/10.1111/mm…

DpaA detaches Braun's lipoprotein from peptidoglycan biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Apparently, I’m a keyworker now! Never felt so important.

Happy New Year from all of us at Train2Target! May it be as sparkly as the glitter background of this collage🌟✨✨

Yaih! Well done!