Kirsty Woods

Resistance training not only prevents muscle loss of aging, but has profound benefits on inflammation, insulin sensitivity, and the immune system. Lift weights and you'll fight aging, maintain a healthy immune system, and avoid weakness and frailty.

🔥Metabolic flexibility🔥 F, 48: Presented after a 10kg ⬆️centrally. WITHOUT any significant weight loss she has⬇️waist by 5cm's & ⬆️her fat burning from just 18% --86%. ✔️⬇️bloating & IBS ✔️⬇️hunger & cravings ✔️⬆️energy & feeling fitter @MHS_tweeting #ECAL #METSIQ

We don't need as much variety as we think...

This study on visceral fat loss blew my mind... It found that sustained visceral fat reduction over years was linked to preserved brain volume and cognitive function in middle age. They tracked people for up to 16 years, and those who lost more visceral fat during an initial diet + weight loss intervention had less brain atrophy and higher cognitive function even up to a decade after the intervention ended. But it was only visceral fat, not subcutaneous fat or even body weight, making the difference. There was no association between subcutaneous fat loss or BMI improvement and brain volume or cognitive function. Managing visceral fat levels may truly be the key to keeping a sharp and healthy brain with age.

You better not skip leg day... Low calf circumference (<35 cm) independently predicts higher mortality risk in older adults, whereas high calf circumference (>38.5 cm) is associated with reduced mortality. Calf circumference is mainly used as a practical proxy for skeletal muscle mass. Graph: PMID: 40702088 Studies: PMID: 34648208; PMID: 36156674

TMS (Transcranial Magnetic Stimulation) takes advantage of neurophysiology to provide safe and well tolerated treatment for many resistant conditions with high potential reward. I suspect exercise could have an additive effect...

Muscle loss is not a given when metabolism is measured and managed... @MHS_tweeting

Dr. Benjamin Bikman just flipped the cholesterol script: Higher cholesterol in older adults = longer life and lower risk of Alzheimer's (peer-reviewed studies confirm it). Low cholesterol? Higher mortality risk and significantly elevated Alzheimer's odds. Why? Every cell in your body makes cholesterol because you need it: - For strong cell membranes - For healthy mitochondria (energy factories) - For hormone production (including sex hormones) Bikman: “Don’t be afraid of cholesterol.” Especially if your LDL is high but your triglyceride-to-HDL ratio is low — that pattern is generally protective. The old “cholesterol = bad” narrative is crumbling fast. What’s your take—still scared of high cholesterol, or rethinking it after seeing the data?

@DoctorTro @Brady_H I think its important to recognise the importance of BP as one of many markers, but as with anything all patients are individual :D

@Brady_H @MetabolicEP CGMs bad CBP good - Brady Holmer 2026 🧐

Continuous blood pressure monitors will be the most important health metric tracker of the century. Non-dipping blood pressure at night raises CVD/mortality risk by 38% even when overnight blood pressure is normal! There’s not a single preventable disease that high blood pressure doesn’t negatively impact.

@UKLowCarb Correct, thanks for clarifying :)

@MetabolicEP Skeletal Muscle Mass ? (SMM)

>>> Body Composition & Metabolic Health <<< M, 33, presented to metabolic clinic in September after losing 50kg with low carb, but reaching a WL plateau and energy slumps (Sep). Recommendations: ➡️Protein ➡️Resistance training ➡️Electrolytes 1/2

@TurtonJessica @kieron_rooney

As this video suggests fatigue & pain can have metabolic origins. In clinic this can often look like patients naturally increasing activity or doing things around the house without an afternoon nap. youtu.be/yAVTahVbr74?si… Not a miracle cure, but worth exploring 💪

In February he had only 'lost 1kg' but had his body composition change by >14kgs 😲💪 Weight: 87.2kg --> 86.2kg RMR: 2477kg --> 2408kcal This case study goes to show how our health is more than just a number on the scales, and the role of metabolic data in patient management.

Major life hack: Be grateful. Harvard researchers found that gratitude was linked to significantly lower risk of all-cause mortality. The way you choose to perceive the world impacts every single area of your life. Choose wisely.

I just read a fascinating review on myokines, and it changes how we think about exercise. Your muscles are not just for movement. They act like an endocrine organ, releasing signaling molecules during exercise that communicate with the brain, fat, liver, pancreas, bone, and immune system. For example: • IL-6 from muscle increases glucose uptake and fat oxidation • Irisin and meteorin-like help turn white fat into metabolically active brown-like fat • Cathepsin B and irisin can increase BDNF and support brain plasticity • Myokines like IL-15 may even improve skin aging • Exercise-induced IL-6 also triggers anti-inflammatory pathways Researchers have now identified 650+ myokines that coordinate whole-body adaptations to exercise. In simple terms, muscle contraction sends biochemical signals that regulate metabolism, cognition, inflammation, and tissue health across the body. Exercise is not just about burning calories. It is system-wide molecular communication.

A single session of exercise increases anti-cancer myokines & suppresses cancer growth.