Michael J Harrop

There's a cure. I need your help to obtain it. @SecKennedy #MAHA #chronicdisease #microbiome #FMT #fecaltransplant #medicine #gutmicrobiota

@GenXCanuck @DocPriyamMD @obinson So you didn't even bother to read the information, and instead opted to share an uninformed, erroneous, and harmful opinion.

@MichaelJHarrop1 @DocPriyamMD @obinson That's what family and friends are for 😁

A 35-year-old man sat in our OPD yesterday and broke down in tears. He’s physically perfect on paper, but his life has become a prison. Every single morning, he sets his alarm for 5:00AM. Not to hit the gym or get a head start on work, but because he needs at least two hours to use the bathroom 4 times before he can even think about leaving for the office. By the time he reaches his desk, he’s already exhausted. He averages 7 bowel movements a day. His personal life is non-existent. He avoids dates, social gatherings, and even long drives because of the constant, looming urge. The most heartbreaking part? He’s done every test imaginable: • Colonoscopy: Normal. • CT Scans: Normal. • Blood work: Normal. • Stool tests: Normal. To the world, he looks healthy. To his doctors, his results are fine. But he feels like he’s losing his mind. This is the brutal reality of Irritable Bowel Syndrome (IBS). It’s often a diagnosis of exclusion. It means we have ruled out the visible diseases, but the dysfunction remains If you’re struggling with this, please know: "Normal" test results don't mean your pain isn't real. We have to stop telling patients they are fine just because the scans are clear.

@GenXCanuck @DocPriyamMD @obinson The problem is accessing high-quality donors: forum.humanmicrobiome.info/threads/the-fd…

@DocPriyamMD @obinson His medical team should consider a fecal transplant from a healthy donor. We are seeing resolution of signs in some veterinary patients. The modern world has decimated the microbiome in some people.

@LaumbRobin @Bompibjornerik @paulsaladinomd @MrBeast I've tried every diet, including 100% raw ones that included raw, fermented meat. Diet comes nowhere close to FMT. There are host-native microbes that have been evolving alongside us for millions of years. They're not in/on food. humanmicrobiome.info/diet/

@MichaelJHarrop1 @Bompibjornerik @paulsaladinomd @MrBeast You do you know that if you eat proper food it's not sterile? You do know some microbes can only survive on, say, sugars - while others thrive on fats? There's millions of combinations? So yes, you starve some, add some and feed some by changing your diet properly.

Hey @MrBeast, video idea for you: let's fix your Crohn's disease with diet. Give me 60 days. I know it is possible have seen MANY people reverse IBD (UC & Crohn's) with an Animal-Based diet or something like it.

@Upgrade57531690 @OliverOtis00 @cptdankkk You're right about possibly getting worse, but it's not due to "matching", it's due to donor quality. * forum.humanmicrobiome.info/threads/the-fd… * humanmicrobiome.info/fmt/ Mr Beast absolutely could and should help find super-donors.

@OliverOtis00 @cptdankkk Yes, there are FMT programs, but they’re: - Mainly for recurrent C diff patients - UC, Crohn’s, IBS are still mostly trials - Donors are heavily microbiome screened, but it’s not true “matching” like organs - Results vary widely: Some improve, some don’t, and a few can worsen

MrBeast opens up about living with Crohn’s disease "When I was 15, I just started going to the bathroom 8, 9, 10 times a day not digesting any food. You drop weight rapidly and it hurts like crazy, it feels like someone's stabbing you in the gut with a knife constantly" "I'm on an extreme medicine called Remicade where you basically nuke your immune system. I just got the flu, I got covid six times, I got shingles, I get sick all the time" "It's pretty brutal to be honest. I live life on hard mode"

@LaumbRobin @Bompibjornerik @paulsaladinomd @MrBeast That's not true. Diet doesn't add microbes, and it generally doesn't remove problematic ones.

@Bompibjornerik @paulsaladinomd @MrBeast The reason fecal transplant works is because it gives a better microbiome. There is another way of killing of the bad bacteria and getting good ones to flourish. Animal based or carnivore does that without have poo up your bunghole.

@wrless1 @katiewr31413491 The medical cabal won't give you FMT. You'll have to take it: forum.humanmicrobiome.info/threads/the-fd…

@katiewr31413491 How about instead of just monitoring when a person will explode we do something helpful and treat them like With fecal transplant? Improve that gut micro biome thus improving ASD symptoms. The medical Cabal gives us nothing. they suck.

Worth a try. ⭐️⭐️⭐️ Feasibility of forecasting self-injurious behavior among autistic youth using wearable sensors. pubmed.ncbi.nlm.nih.gov/42062348/

@DrSeanOMara Fermented foods are way overhyped. They contain non-host-native microbes. They will not restore essential host-native microbes that have been evolving alongside us for millions of years. humanmicrobiome.info/probiotic-guid…

A fecal microbiota transplant reduced alcohol cravings by 90% in clinical studies. If you change the gut bacteria, you can change behavior. Your gut microbiome influences more of your health than your physician does. And the single most overlooked strategy for building it costs less than a dollar a day: fermented food.

@hoping4truth @Humanspective FMT from safe & effective donors will never be available, because people are too lazy to take the necessary action: forum.humanmicrobiome.info/threads/the-fd…

@Humanspective Fecal transplant needs to be normalized in the United States. It is an incredible therapy with potential to reverse many “autoimmune” diseases. Being done in Australia to cure Crohn’s disease.

🚨 I’ve heard a lot in my time.. this is unbelievable They found a gut microbe that completely eliminated tumour cells.... and they found it in a FROG. Outperforming chemo and checkpoint inhibitors A 100% response rate... they tried to re-introduce the cancer to the animals... and “the tumours couldn’t grow” Jimm Dore [@jimmy_dore] - “It seems like a crazy idea... 'hey let’s take some bacteria from a frogs gut... see if that cures cancer’... how do they come up with that?” Nicolas Hulscher [@NicHulscher] - “They can’t just patent a natural gut bacteria... we need independent scientists on this... they must have had an idea previously.. some previous research.. the understanding that these amphibians don’t usually get cancer... they went to the Microbiome”

@Nikolas_Dubinko @SecKennedy Donor quality appears to be mostly luck. You either are or are not. Most interventions only change the percentages of what's already there. FMT from a super-donor is probably the only thing that can make a donor better.

@MichaelJHarrop1 @SecKennedy Yo I’m 16 and with your guidance, I think I could become a high-quality stool donor by the time I’m 18 I’m down for saving thousands of lives dm me

There's a cure. I need your help to obtain it. @SecKennedy #MAHA #chronicdisease #microbiome #FMT #fecaltransplant #medicine #gutmicrobiota

@soupvector @PaulSaxMD @NEJM "Professionals" like you are why patients like me don't have access to an existing cure.

@MichaelJHarrop1 @PaulSaxMD @NEJM Just point to one of those studies that clearly shows convincing evidence that a human phenotype outside the gut is meaningfully changed by FMT. I'm not denying the potential, nor that I lack deficits, I'm just asking you to point to specific evidence.

For-profit companies want you to send them your poop. For a fee, you’ll get a “bespoke” report and suggestions for how to fix your microbiome. Here’s why this burgeoning market is right now not worth s—t. @NEJM voices.nejm.org/doi/full/10.10…

@soupvector @PaulSaxMD @NEJM Wow, you're incredibly lazy and wilfully ignorant. A professor of medicine and infectious disease... I should not be the one educating you. Disturbing. maximiliankohler.blogspot.com/2021/06/idiocr…

@soupvector @PaulSaxMD @NEJM "I have yet to see convincing report that a fecal transplant has resulted in cure or cause of diabetes, change in mental health, or any of the other phenotypes attributed to the gut microbiome" is your deficit. So I linked you to that evidence.

@MichaelJHarrop1 @PaulSaxMD @NEJM I'm not sure you read what I wrote. The potential is very exciting, and there's much to learn. What, specifically, is my deficit?

@soupvector @PaulSaxMD @NEJM That's a deficit on your end. See away: humanmicrobiome.info

@PaulSaxMD @NEJM Great commentary, Paul! As much as I want to see real advances in microbiome science, I have yet to see convincing report that a fecal transplant has resulted in cure or cause of diabetes, change in mental health, or any of the other phenotypes attributed to the gut microbiome.

@mewsreporter @fatherofboys083 @newstart_2024 Yes it is.

@fatherofboys083 @newstart_2024 A fecal transplant is not done orally. 😅

Two patients got a poop transplant for C. diff… and suddenly started growing hair again. That unexpected result hooked Dr. Sabine Hazan. She saw alopecia areata disappear after fecal transplants from healthy donors — and in other cases, it appeared. So she started digging: is there a specific microbe linked to hair growth? Could the same microbiome signals be involved in Alzheimer’s, autism, or Parkinson’s? Her own experience with Alzheimer’s improving after a fecal transplant only deepened the question. Her blunt takeaway: “There’s got to be something more to poop than just poop.” It’s a fascinating window into how much we still don’t understand about the gut microbiome and its potential role in neurological and autoimmune conditions.

@Neuroscope_mp The bad news is that no one seems interested in solving the donor quality problem: #post-1370" target="_blank" rel="nofollow noopener">forum.humanmicrobiome.info/threads/the-fd…

The good news? Clinical trials are already testing whether changing this microbiome can help PD patients. We’re seeing trials on fecal microbiota transplant (FMT) and targeted probiotics to see if they can reduce inflammation and slow progression. Results are early but promising in some cases. pubmed.ncbi.nlm.nih.gov/38686220/ explorationpub.com/Journals/ent/A… pubmed.ncbi.nlm.nih.gov/39367119/

Parkinson’s patients show a consistent gut bacteria shift across many studies. This creates low-grade inflammation in the gut that we often don’t even feel — and that inflammation can feed into the gut-brain axis. ❌Depleted (good ones, anti-inflammatory, protective): • Prevotella • Faecalibacterium • Roseburia, Blautia, Lachnospiraceae (these make protective SCFAs) 🔗 SOURCE: nature.com/articles/s4146… pubmed.ncbi.nlm.nih.gov/25476529/ pmc.ncbi.nlm.nih.gov/articles/PMC10…

@DuaneStorey @StarBoy_69_15 Your response reveals that you didn't even read the info in my first tweet. That's an example of what the post criticized. I've done FMTs from 15+ different donors. You should read the information if you genuinely want a cure. x.com/chydorina/stat…

@MichaelJHarrop1 @StarBoy_69_15 FMT won't solve covid dude.. It's a neat idea but the microbiome has mostly been a bust. I've had a FMT, I know. If you want a FMT so bad, just go grab some of your friend's feces and get going, that's how easy it is.

Spent some time reviewing all the current long covid trials under way. Over a billion dollars allocated to them. We're all goners.

@DuaneStorey @StarBoy_69_15 So whose fault is it then? The situation will never be solved without broad patient demand/action. If you're blaming someone else (who?), it's still patients' duty to push those entities to solve the problem.

@MichaelJHarrop1 @StarBoy_69_15 Lots of problems, I don’t think patients are one of them. I’ve actually had a FMT before.

@StarBoy_69_15 @DuaneStorey That already exists: x.com/MichaelJHarrop…. The problem is that the patient community is too lazy to help.

@DuaneStorey Dude it honestly pissed me off. We are so fucked. We need someone that is actually looking for a cure, not a dollar sign.

@DuaneStorey Yep. We're goners because patients are too lazy to take action on an existing cure, and it can't be patented, so people with financial interest won't pursue it: Pt 1 forum.humanmicrobiome.info/threads/the-gu… Pt 2 #post-1370" target="_blank" rel="nofollow noopener">forum.humanmicrobiome.info/threads/the-fd…

@LazarusLong13 It's hard because finding a safe & effective donor is extremely difficult: #post-1370" target="_blank" rel="nofollow noopener">forum.humanmicrobiome.info/threads/the-fd…

if I couldn't afford the $9,411, $19,680, or was not approved since I am immunocompromised? In other words, how difficult is the DIY Colon Biome Transplant (aka fecal transplant)?

Airborne Fecal Transplant (Strep A is airborne, the antibiotics wiped out the poor kid's colon's commensal bacterium, allowing c diffile to spread) Free article below. But I got curious - what if....?