Nancy Moate

🚨 Anti-Parasitic Human Medications Researched for Potential Roles in Cancer Treatment 1️⃣ Ivermectin Ivermectin is an antiparasitic medication that works by increasing chloride ion permeability in parasite cell membranes, leading to paralysis and death. In research settings, it has also demonstrated anti-inflammatory effects through inhibition of certain cytokines and has been investigated in preclinical studies for potential anticancer mechanisms. 2️⃣ Mebendazole Mebendazole is commonly used to treat intestinal parasitic infections such as roundworms, hookworms, and whipworms. It acts by disrupting glucose uptake in parasites, leading to energy depletion and death. Laboratory studies have explored its ability to interfere with microtubule function, a process relevant to cancer cell division. 3️⃣ Albendazole Albendazole is an FDA-approved anthelmintic drug used to treat parasitic infections, including hydatid disease caused by Echinococcus granulosus. Research has examined its effects on cell division and metabolic pathways, leading to interest in its possible anticancer activity in experimental models. 4️⃣ Niclosamide Niclosamide is an FDA-approved drug used to treat tapeworm infections. In preclinical cancer research, it has been shown to inhibit several signaling pathways involved in tumor growth, including STAT3, Wnt/β-catenin, mTOR, and Notch. Studies suggest it may suppress cancer stem cell activity and tumor progression in laboratory models. 5️⃣ Artemisinin Artemisinin is a natural compound derived from Artemisia annua and is widely used in antimalarial therapy. Beyond its antiparasitic activity, it has demonstrated anti-inflammatory and antiviral properties. Research has explored its iron-dependent cytotoxic effects on cancer cells in experimental studies. 6️⃣ Praziquantel Praziquantel is primarily used to treat schistosomiasis. In laboratory studies, it has been investigated in combination with chemotherapeutic agents, where it appeared to enhance growth-inhibitory effects and activate apoptotic pathways in certain cancer cell models. 7️⃣ Pyrvinium pamoate Pyrvinium pamoate is traditionally used to treat pinworm infections. Research suggests potential anticancer effects, particularly in pancreatic cancer models, largely attributed to its ability to disrupt mitochondrial function in cancer cells. 8️⃣ Levamisole Levamisole is an antiparasitic and immunomodulatory agent. Historically, it has been studied as an adjuvant therapy in certain cancers, including melanoma and colorectal cancer, particularly in combination with fluorouracil (5-FU), to enhance immune-mediated anticancer responses. 9️⃣ Suramin Suramin has demonstrated activity against various cancer cell types in research studies, including prostate and breast cancer models. However, its clinical use is limited because of significant toxicity, particularly neurotoxicity, requiring careful dose consideration. 🔟 Quinacrine Quinacrine has shown anticancer effects in both cell culture and animal studies. Research indicates it may suppress NF-κB signaling while activating p53 pathways, leading to apoptosis in cancer cells under experimental conditions.

🚨 U.S. test scores are in a generation long freefall, reading scores just hit their LOWEST point since 1909. The biggest drops are among the lowest-achieving kids. We’ve failed an entire generation. Decades of federal bureaucracy, teachers’ unions protecting failure, and schools more worried about pronouns and DEI than reading, writing, and math. Throw in social media rotting their brains and you’ve got a perfect storm of stupidity. Education Secretary Linda McMahon: “The most important thing we can do for our children is make sure they can read and do math. We have failed them.” The solution... ABOLISH THE TEACHER'S UNIONS

Hakeem Jeffries: “Not a single undocumented immigrant in this country gets a dime of federal taxpayer dollars for any part of Medicaid coverage.” Lying under oath is a CRIME. CHARGE HIM.

A peer-reviewed paper published last year in the journal Bioethics by two professors at Western Michigan University School of Medicine argues that it is "morally obligatory" to genetically engineer ticks to spread alpha-gal syndrome, a permanent condition that makes you violently allergic to red meat. The paper is called "Beneficial Bloodsucking." Their argument: if eating meat is morally wrong, then preventing the spread of a disease that forces people to stop eating meat is also morally wrong. Scientists should gene-edit lone star ticks to enhance their ability to carry alpha-gal syndrome and expand their range into urban environments to infect more people. They call this a "moral bioenhancer." They frame releasing genetically modified disease-carrying ticks as a "vaccination" that only "infringes" on your bodily autonomy rather than "violating" it. The distinction, apparently, is that a tick bit you instead of a government official holding you down. Alpha-gal syndrome is not mild. The CDC estimates up to 450,000 Americans are already affected. Cases have surged 100-fold in the last decade. Symptoms include anaphylaxis. There is no cure. Alpha-gal cases are exploding across the United States. The lone star tick's range is expanding far beyond its historical territory. And two academics at a medical school published a paper arguing this is a good thing that should be accelerated. At what point do we stop treating papers like this as fringe academic exercises and start asking whether anyone is already acting on them?

I asked the Fairfax DA why a child r*pist walked away with only 90 days suspended.