Neel Joshi

🌡️ Sucking the CO2 out of my bedroom turned out to be the final thing improving my already good sleep to great My weekly sleep is now 1st in Los Angeles, 5th in California and Japan and 9th in Amsterdam, so really good Most people have way too high CO2 in their bedroom (1500 to 2500 ppm) because that's what you breathe out and it doesn't get refreshed, I discovered this after getting an @airthings sensor (unaffiliated, I just like it) There's a lot of confusion about CO2, you can't "air purify" CO2 out, it doesn't work like that, also it's not CO, it's CO2, it's what you breathe out, slowly a room will fill up with it and your brain and body will start struggling. You realize CO2 high when you feel a room is "stuffy", too many people breathing out, not enough fresh air coming in If you sleep as a couple the CO2 will be double because you both breathe out for 8 hours. Americans who think HVAC will save them: no most HVAC recirculates air it does not refresh air (very new houses do though), also outside US: regular AC just recirculates air, for CO2 to be removed you have to bring in fresh air from outside (like a bathroom fan sucking out air to create pressure to bring in new air, or an actual refresh air system). Opening a window is a nice idea but these days (?) almost everywhere is loud and you'll wake up from stuff to also slowly destroy your sleep Most people also sleep WAY too hot around 23°C/73°F but don't realize it, because that's a good temperature for a living room in the day, but way too hot for good sleep. Most studies show the ideal bedroom temperature is around 15-18°C / 59-65°F. Above that your body will not enter deep sleep meaning 8 hours of sleep in a hot bedeoom might just be 5 hours of actual sleep (I see people from warm countries consistently not accept this, so my rebuttal is: if you sleep so well, why is your GDP so low). The fix is installing a powerful AC, not blasting it in your direction (that's bad for your nose), and cleaning it regularly. I run my AC at 17°C/62°F with fan on 3/4 strength directed downward so we don't feel the air hitting us directly (important). Many ACs suck, we had Daikins and they suck, they go on and off repeatedly after hitting their target temperature, which wakes you up too, you need an AC that has constant cold air flow, we got Mitsubishi Electric which is great One other thing that I like and use every night is the @curaofsweden weighted blanket (also unaffiliated), it's 9kgs/20lbs (related to your body weight so buy the right one) which creates deep pressure and compression on your body which calms your nervous system, I think this is also related to modern bed sheets/blankets: they used to be made of organic materials like cotton etc and were way heavier than modern lightweight polyester/plastic sheets so you don't get that effect anymore, with a weighted blanket you do On top of that weighted blanket, I have a blanket that I put over it usually around 5am when my core body temperature hits the lowest point, of course this makes a good argument for those temperature regulating beds (but that's too much even for me for now) Outside of bedroom what also really helps my sleep is exercise, I lift weights about 3-4x per week and try hit 30min gym cycling for cardio 2-3x per week too. Especially the lifting puts me in a coma. Yesterday I squatted 120kg for example and you just feel like falling into your bed after that, also deadlifts and benchpress etc Anyway this is how I made my already good sleep great, I hope it helps! 😊

Met several childhood friends this week. Shocked by how many ave up on their ambition and are now housewives. And I'm talking about the ones we called prodigies. Same story for everyone. At some point they evaluated that what they're earning is a meaningless amount compared to their partners' family business income. So they stopped working. This is terrible short-term thinking. Long back I read Erich Fromm, who explained the primitive psychology behind every parent-child relationship that I believe applies here too. He argued that beneath the love that parent and child feel for each other, there is a transaction at play. The exchange of security for obedience. Parents give security, and in exchange expect obedience, even if they consciously think otherwise. Parents who 'feel' they aren't providing enough are more liberal. The ones who 'feel' they have, demand compliance. Apply this to a marriage where one partner earns and the other doesn't. - the earning partner accumulates unconscious authority, sometimes without wanting it. - the non-earning partner begins to self-limit- opinions soften, needs minimize, disagreements are swallowed. Love remains real but underneath it, the exchange of security and obedience creeps in. It doesn't start as that transaction, it becomes one. The earning partner may never demand obedience and may even actively discourage it. But the non-earning partner's psyche has already done the math. I strongly believe that each individual should work, even if you're making what feels like a meaningless amount. Do it simply to keep for your sense of independence and freedom.

@JamieKerstetter @andrewneeme Funny af

@andrewneeme Your nemethith?

This is my evil twin euro crusher brother and he must be stopped at all costs.

The word "psychedelic" was invented during a poetry battle. Aldous Huxley proposed "phanerothyme" with the line: "To make this mundane world sublime, take half a gram of phanerothyme." Psychiatrist Humphry Osmond countered: "To fathom Hell or soar angelic, just take a pinch of psychedelic." Osmond won. He debuted the word at the New York Academy of Sciences in 1957. We almost ended up calling them "phanerothymes."

Who are you taking on a date? 🤔

Funny af

Companion Labs is here to build an AI-native entertainment company. We are thrilled to announce that we've just raised $2.5M led by @peakxvpartners @_surgeahead along with @All_IN_CAPITAL, @untitledvc_ , @DeVC_Global and many incredible angels.

@hubermanlab @esaagar Is two drinks a week better, or 8 drinks hammered on a single day, once per month? @hubermanlab

@esaagar And my stance on alcohol is 0 better than any, 2 drinks per week probably OK for non alcoholic adults. And the data may have ping ponged a bit on wine but as covered recently, the best read of the data say 0 is best (if talking health; you do you). hubermanlab.com/episode/what-a…

Weed is a weapon of mass destruction

Mushrooms evolved into psilocybin twice. A fascinating new study has revealed that psilocybin—the psychedelic compound in magic mushrooms—arose not once, but twice, through entirely independent evolutionary events in distant corners of the fungal kingdom. In the familiar Psilocybe species, psilocybin is assembled via a well-characterized four-enzyme pathway. Yet when scientists examined certain small, drab fiber cap mushrooms (from genera like Inocybe and allies), they discovered a completely unrelated biochemical assembly line: different genes, different enzymes, different intermediate steps—yet the end product is chemically identical. This is a remarkable case of convergent evolution: two lineages, with no shared ancestry for this trait, each invented their own molecular machinery to manufacture the same powerful molecule. Why fungi bother making psilocybin at all is still unclear. Some hypothesize it serves as a defense chemical (the blue bruising reaction in damaged Psilocybe tissue hints at this), while others propose roles in inter-species signaling or entirely unknown ecological functions. Whatever the benefit, it was evidently strong enough for natural selection to favor it twice, in very different habitats. The finding also carries immediate practical value. With psilocybin advancing in clinical trials for treatment-resistant depression and other conditions, having two distinct biosynthetic pathways gives researchers multiple genetic toolkits for engineering microbes or yeast to produce the compound in bioreactors—potentially making therapeutic-grade psilocybin far cheaper and more scalable. In the end, nature quietly solved the same chemical puzzle twice, deep in the soil, millions of years apart—and only now are we stumbling across its elegant, redundant handiwork. [“Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms.” Angewandte Chemie International Edition, 2025]

I was wrong about this btw. Someone sent me a "blockerless solver" that allows hands to overlap. While it's true that blockers introduce combo-level complexity (different suits of the same hand doing different things), they tend to reduce range-level complexity!

Ai -Khanoum(Khanum), (meaning "Moon Princess") is a lost Hellenic city of 4th-mid 2nd century BCE city, in northern Afghanistan at the confluence of the Kokcha River and the Amu Darya. (1/n)

@pedrogaragnani Curious about your thoughts and your poker journey!

I’m thinking about writing about random stuff on twitter and given this is my first non-reply tweet I wanna see what kind of interaction I get

@tombos21 Love your tweets bro, keep posting more!

Stand-Up/Squid Game is a fascinating variant from a poker theory perspective. Each player values the pot differently depending on their "squid utility", which is a function of how many are left and if they've already have won a pot (among other factors). We can model that effect with antes. That means when you play these games, there's a huge "virtual squid ante" that you can't see, often many times larger than the pot itself. Everyone values that ante differently, so you get strange and interesting strategy pairs. Graph Credit: Poker Giraffe

Worked as a carpenter. Got taunted by many when young daughter started playing cricket with boys in the neighborhood. But he stood by her. Made her first bat with his own hands. Got her enrolled in an academy. Travelled far everyday to take her to training and decided to pick and

@DipshikhaGhosh These comments make me lose hope jfc, this is unreal

“But what about your father? Is he also trash?” Yes, many fathers are absolute trash.

@DivijaBhasin What a horrific, heart breaking comments section

If you open the newspaper and see the crimes being reported, 90% of it is always men. There is a strong need for our education system to be given a feminist foundation so men learn to respect women. Here are some of the things that can be done - - Ensure all textbooks use gender neutral pronouns and not “he” when talking about people. Women are currently seen as the “other” gender and clubbed in the same category of “men” - When giving examples, talk about women who have strong careers and are financially independent. Currently a lot of examples in textbooks show women only in “nurturing” “motherly” roles - Fire all male employees in schools that have a problem with female students wearing short skirts. They problem isn’t the skirt, the problem is sexualizing little girls. - Do not segregate students. Let boys and girls sit together. Stop over sexualizing their friendships. - Have an entire compulsory subject or module which teaches about women’s health and periods. Ensure both genders are taught about it. - Teach all kids psychology starting from class 1 mandatorily. - Include women’s history in textbooks. When teaching about the partition, talk about the women who fought for our freedom. Make sure this is in the regular section and not some pink little corner of the book under “women’s contribution”.

"sketch briefly Sir Walter Rayleigh"

Trump: Rigged election. *points to Erdogan* He knows about rigged elections better than anybody.

my top 4 tech twitter tweets of all time

Nothing but love and respect for @Aella_Girl