Sun Mu

@ChristosArgyrop You forgot bombing innocent civilians - mostly children

@kidney_boy You seem happy. Gaza's dead children in that box?

On Memorial day I finally demoed Apple Vision Pro. Blown away. And yes, I do bleed 6 colors.

@dinukawrpt Classical Bartter syndrome patients are polyuric because of decreased urinary concentrating ability which is due to mTAL dysfunction and high prostaglandin production. Tolvaptan won't be helpful and it might theoretically worsen. Tolvaptan itself causes polyuria and polydipsia.

Can we use Tolvapton to treat Bartters syndrome instead of salt to reduce their large water intake ? #askrenal

@VelezNephHepato Is 2-6g/g doubtful because of deceased creatinine excretion? Can you please elaborate. Thank you

Impressive indeed. Absolutely, very high UPCR is unlikely to b entirely false. In oligoanuric pts, UPCR ~2-6 g/g may cast some doubt about degree of proteinuria and in those cases lipiduria is a very helpful finding to confirm nephrosis. So I’m never quick to trash UPCRs in AKI.

“Cr is 10, UPCR 22 g/g” -“well, cannot rely on UPCR in AKI, so…” Urine says: 👇🏼 #OvalFatBodies #MassiveLipiduria #UrinarySediment @OchsnerNephro

@nephondemand @Ask_Renal Thank you sir for your kind response. What should be the duration of treatment before labelling true resistant Hypertension? Thank you

@NephBean @Ask_Renal See this study's inclusion criterion: pubmed.ncbi.nlm.nih.gov/21444835/ Courtesy of SearchNephX.com

What should be the duration and dosage of antihypertensive medications when we label someone as resistant Hypertension? @Ask_Renal #askrenal @hswapnil

@askrenal Better ask Chat-gpt.

An Ask Renal question for the #NephTwitter #NephX by - @NephBean 👇 twitter.com/NephBean/statu…

What happens to Urinary NH4+ excretion in Proximal RTA? @Ask_Renal @askrenal What about this statement on uptodate?

@kidneydoc101 In retaliation Israel killed more than 10000 Palestinians with almost half being children. I won't ask you to do the math in terms of US or UK pmp. Every innocent human life is precious. You won't understand that because you are full of hatred. You are a disgrace 👎🏿👎🏿👎🏿👎🏿👎🏿👎🏿👎🏿

The world has gone mad…. Don’t forget on #Oct7 #Hamas butchered 1200 people, injured 6000+ & took 240 #Hostages In #UK, pmp equivalent to murdering 8000, injuring 40000 & 1600 hostages Or in #USA 44,000 murdered, 220,000 injured & 8826 hostages #raped #burnedalive #mutilated That’s the reality; that’s what they’ve promised to do again & again #NeverAgainIsNow (FYI death toll on #Sept11 2977 in a population ~ 37x Israel’s)

Do you use prophylactic calcium gluconate in plasma exchange by membrane plasma separation? If yes, then what's the protocol? #askrenal @Ask_Renal @ask

@kidney_boy Both AVP-D(CDI) and AVP-R(NDI) have been found with lithium therapy and polyuria in these patients shouldn't be presumed to be AVP-R.

Why does lithium cause nephrogenic diabetes insipidus? #AskRenal

#askrenal @GlassockJ @roger

@manasib33 1. Selective glomerular hypofilration (shrunken pore syndrome) 2. Other causes that increase serum cystatin c or decrease creatinine. measuredGFR may be more informative in this case than urinary creatinine clearance.

How do you interpret Cystatin GFR of 29 and Creatinine EGFR 59 at the same time? Can it be due to older age and obesity? #askrenal

@RenalPathLabs ALECT2?

Renal Path Quiz I am a rare disease.Common in Hispanics,rarely seen in India. When found, Renal Pathologist is delighted to see me! When present with Diabetes, it is tough to pick me. Who am I? #RenalPathLabs #RenalPathologySociety #AskRenal #AskRenalPath #NephTwitter #GlomCon

In a kidney biopsy with 15 glomeruli with 90% being globally sclerosed and 1 glomerulus showing segmental sclerosis, be labelled as global diffuse glomerulosclerosis or fsgs? @DrGeetikaSingh1 @MPAlexanderMD @SethiRenalPath @draalok @renalpathdoc @DrRizwanRasheed @tiff

@DrGeetikaSingh1 @NephBean @MPAlexanderMD @SethiRenalPath @Richard @nephrosharma I usually only count as a percentage of intact glomeruli too. I think of this as a measure of activity and a globally sclerotic glomerulus cannot have an active crescent. As such, it does not make sense to me to use it in the denominator.

@NephBean @MPAlexanderMD @SethiRenalPath @DrGeetikaSingh1 @renalpathdoc @Richard I also calculate from total Glomeruli. Important for the prognosis is how many Glomeruli remain healthy. I write in the Report how many are global +partial sclerosed and how many with newer lessions. Renal Score from Brix et al is really good. The ist an App for cell Phone

@DrGeetikaSingh1 IF negative makes early membranous unlikely. Shouldn't matter what do we call it as long as the patient is treatment responsive (secondary causes should be ruled out)

73 /F with NS. Bx- 8 gloms, 1 globally sclerosed, rest normal. IFTA 5%. IF negative. EM - NA. You would call this > 1. MCD ( attribute mild chronicity to age) 2. MCD, unsampled FSGS cant be excluded 3. Minimal change histology 4. Nonprolif glom histology #askrenalpath

@SethiRenalPath @DrGeetikaSingh1 @MPAlexanderMD @renalpathdoc @Richard @nephrosharma Thank you sir

@DrGeetikaSingh1 @NephBean @MPAlexanderMD @renalpathdoc @Richard @nephrosharma I usually use the total number of glomeruli. Eg-3 out of 10 glomeruli show crescents, regardless of how many are globally sclerosed. But it is important to also give the number/percentage of glomeruli that are globally sclerosed so the clinician gets a good idea of the chronicity

In a kidney biopsy with crescents, is the percentage of crescents calculated from total number of sampled glomeruli or just the non-globally sclerosed glomeruli? @MPAlexanderMD @SethiRenalPath @DrGeetikaSingh1 @renalpathdoc @richard

@DrGeetikaSingh1 @MPAlexanderMD @SethiRenalPath @renalpathdoc @Richard @nephrosharma Thank you ma'am

@NephBean @MPAlexanderMD @SethiRenalPath @renalpathdoc @Richard My understanding is : Calculate percentage crescents from the non- globally sclerosed glomeruli. This will give the clinician an idea of the extent of severe glomerular injury in salvageable kidney and help plan Rx accordingly @nephrosharma - I remember asking the same Q