Lucile Noyer

I’m excited to share our new paper published in @SciImmunology ! Together with @Liwei_K, we show that CLNS1A is essential for T cells and autoimmunity. 1/3 doi.org/10.1126/sciimm…

Noyer et al. @Feskelab show that a novel mutation in ORAI1 results in constitutive CRAC channel activation while abolishing stimulation-induced channel opening. The mutation is associated with severe immune dysregulation, incl. altered T & NK cell function hubs.la/Q03QYB7L0

CLNS1A promotes autoimmunity through epigenetic and transcriptional regulation of DNA repair and cell cycle progression in CD4 T cells @SciImmunology @NoyerLucile @St_Feske science.org/doi/10.1126/sc…

New research from @Feskelab suggests that chloride nucleotide-sensitive channel 1A (CLNS1A) is a key transcriptional and epigenetic regulator of pathogenic #CD4 #Tcells in mouse models of #autoimmune and inflammatory diseases. scim.ag/3HHrOYJ

Thank you to the best co-first @Liwei_K, @Feskelab, and all the co-authors that made this happen! @nyugrossman

We dive into the role of CLNS1A (chloride nucleotide sensitive channel 1a) in T cells. Surprisingly, it does not regulate chloride currents in T cells. We show that CLNS1A interacts with PRMT5, functions as an essential epigenetic regulator of DNA damage response machinerie. 2/3

I’m excited to share our new paper published in @SciImmunology ! Together with @Liwei_K, we show that CLNS1A is essential for T cells and autoimmunity. 1/3 doi.org/10.1126/sciimm…

The Feske Lab is on fire at the Channels and Transporters in Immunity FASEB conference! #CTISRC #FASEBconference #ICTImmunityConference

Extended call: 3 more weeks to apply for a postdoc position in our lab focused on the role of iron in pancreatic cancer and drug resistance. DM for any questions. health.au.dk/en/about-healt…

Join the IonLab electrophysiology core facility at NYU Langone Health as a Research Associate! Contribute to innovative research on ion channels in health and disease. Apply now at #tab-id-1" target="_blank" rel="nofollow noopener">jobs.nyulangone.org/job/18341529/r… #ResearchAssociate #Pathology #IonLab #Electrophysiology

Very grateful for this award to @Feskelab and excited to continue investigating the role of ORAI2 in melanoma together with #twitterless Liwei Wang!

@pedrosvdr @NortheasternCOS @Northeastern Congrats 🥳🥳🥳

Beyond excited to share I'll join the Department of Biology @NortheasternCOS @Northeastern as an Assistant Professor in January 2024! The lab will focus on understanding how commensal microbes modulate host physiology in health and disease.

Synergy between Orai1 and Orai3 calcium signaling in mediating B lymphocyte metabolic reprogramming in response to BCR activation. Thanks to our wonderful collaborators, Zia Rahman (Penn State) and @Feskelab (NYU). elifesciences.org/articles/84708

A tenure-track faculty position in Immunology is available @NYUGSOM_Path . Applicants should pursue innovative research with direct application to human immunology. Come and join us in New York City! #Immunology #ScienceTwitter nature.com/naturecareers/…

Initial time-of-day of tumor engraftment dictates ensuing tumor size across murine cancer models. Rhythmic trafficking of DCs to dLN governs circadian response antitumor CD8+ T cells via CD80. nature.com/articles/s4158…

I'm very excited to share a review written together with @AymericSilvin @FGinhoux @MiriamMerad in @CellCellPress on macs in health & disease. We share our thoughts on how the field should approach the study of macs & on the field's now pressing questions! authors.elsevier.com/c/1g3VbL7PXiqSi

My fellows are getting jobs. Great, except my lab is shrinking! We will be looking for postdocs to join us in studying how the tumor immune microenvironment (incl. neutrophils) & systemic changes (incl. those caused by stress) control metastasis. Email me: egeblad@cshl.edu

T cell-specific deletion of Orai1 did not exacerbate pulmonary inflammation 🔥 and viral burdens following IAV infection, but protected mice from house #DustMite–induced allergic airway inflammation. 🖊️ By Dr. Stefan Feske at @nyugrossman and team. 📂 bit.ly/3z4S1t5

We are looking for postdocs/scientists to work on multiple funded projects exploring lymphatic transport, T cell trafficking, and lymph node biology! Check us out, shoot me an email, or find me at the Lymphatics Gordon in Tuscany and #SITC22 in Boston! thelundlab.com

Please join us for the first #ICTI free webinar held by @Michael_Cahalan about Ion Channels and Calcium Signaling in T cells. Find out more at ictiseminars.com/calendar

📣We are one day away to kick in the first ever webinar of the Ion Channels & Transporters in Immunity seminar series! Wednesday, October 19th, 2022 11am ET More info: ictiseminars.com/calendar Please share!!! #ionchannels #immunity Zoom link: nyulangone.zoom.us/j/99164969844?…