OxASN: The Oxford Antigen Specificity Network

A role for CD8+ T cells in lupus nephritis dlvr.it/TSWLDP

Highly recommended

Highly recommended

This is a great book, I very much enjoyed reading it and highly recommend it

If this would be helpful to anyone, but you don't want to buy a copy, you can read it for free online: Link: heyzine.com/flip-book/a5dd… Password: BeKind

We have an exciting new story out at @ScienceMagazine's Science Immunology! It is about using #AAV cytokine delivery to change the lung environment. We can boost #lung #Tregs or delivery anti-inflammatory #cytokines, preventing fatal respiratory collapse science.org/doi/10.1126/sc…

Congratulations to @LabListon and the team for this very interesting study

@LabWaggoner @biorxivpreprint @Muzz_Haniffa @sangerinstitute Great study congratulations to the team @Muzz_Haniffa @mo_lotfollahi et al

@biorxivpreprint Hidden immune memory niches in inflammatory skin diseases biorxiv.org/content/10.648… @Muzz_Haniffa @sangerinstitute 🇬🇧

@biorxiv_immuno Great looking preprint. Can’t wait reading it

TCR Signal Strength and Eomes Coordinate CD8⁺ T Cell Fate and Antitumor Immunity in Hepatocellular Carcinoma biorxiv.org/content/10.648… #biorxiv_immuno

Our new book "Self-Doubt" is written by scientists for scientists. You might think you are alone when you doubt your ability or suitability for science - you aren't. We all question ourselves and carry doubt with us daily. amazon.com/Self-Doubt-Ant…

T-SCAPE: T cell immunogenicity scoring via cross-domain aided predictive engine science.org/doi/full/10.11…

Assessment of computational methods in predicting TCR–epitope binding recognition, Lu et al. @naturemethods: "Our analysis revealed that the source of negative TCRs substantially impacts model accuracy, with external negatives potentially introducing uncontrolled confounders. Model performance generally improved with more TCRs per epitope, highlighting the importance of large and diverse datasets. Models incorporating multiple features typically outperformed those using only complementarity-determining region 3β information, yet all struggle to generalize to unseen epitopes. The use of independent test sets proved crucial for unbiased assessment on both seen and unseen epitopes. " nature.com/articles/s4159…

Excited to share our new review on deep learning for structure-based drug design! 🎉 pubs.rsc.org/en/content/art… Authors: @LucyVost*, Yael Ziv*, Charlotte Deane

Great lineup of speakers! I am delighted welcoming you all!

A CD4+ T lymphocyte–specific TCR/GSDMD/IL-2 axis facilitates antitumor immunity @jclinicalinvest jci.org/articles/view/…

Congrats to PhD student, Liam Rashleigh, whose 1st authored paper on gd T cell receptor recognition was published today @Structure_CP cell.com/structure/full… #GDTcellclub @MonashUni @RossjohnLab

@KlebanoffLab @UlrikStervbo @ScienceMagazine Brilliant, this is great, thank you for sharing

🤯Three (!!!) new papers today in @ScienceMagazine on the application of generative AI for the de novo design of peptide/HLA binding molecules! Completely unique 3D structure and binding mode compared with natural TCRs and TCR mimics! Links to papers 👇

Mitochondrial respiration is necessary for CD8+ T cell proliferation and cell fate @NatImmunol nature.com/articles/s4159…

A new Science #Immunology study identifies CD8 #Tcells with enhanced effector function in tumors, which could be leveraged for #cancer treatments. scim.ag/3Ik4aBL

Very much looking forward to the Oxford TCR meeting! 😃 Submit your abstract by Friday