Progress, Potential, And Possibilities

What if the future of medicine isn’t about treating disease after symptoms appear - but identifying risk years or even decades earlier?🩺🩻⚕️ In this @ProgressPotent1 conversation, I sit down with Dr. @DrJulieTChen MD - Chief Medical Officer of Radence and Sidestep Health AI - to explore the emerging world of “disease interception.” We discuss how medicine is shifting from reactive care toward: • ❤️early detection of cardiovascular, metabolic, neurodegenerative, and cancer risk; • 🩸continuous health monitoring and longitudinal biomarkers; • 🤖AI-driven interpretation of complex health data; • 🧬precision prevention and personalized health trajectories; • 🌱and the broader goal of extending healthspan - not just lifespan; Dr. Chen brings a uniquely grounded perspective shaped by years across academic research, integrative medicine, precision health, and the rapidly evolving longevity field. This was a thoughtful discussion about where the science of healthy aging is actually heading - and how the next generation of medicine may focus less on “anti-aging” and more on preserving function, resilience, and quality of life for as long as possible. #Longevity #Healthspan #PreventiveMedicine #PrecisionMedicine #HealthyAging #DiseaseInterception #AIHealthcare #FutureOfMedicine #AgingResearch #Biotech @FINNPartners @FPIPR @RACapitalMgmt

Psychedelic medicine has entered an entirely new era. 🧠🚀 What was once considered fringe science is now at the center of FDA discussions, White House policy initiatives, veteran mental health programs, and a rapidly growing biotech industry focused on neuroplasticity and precision psychiatry. In this @ProgressPotent1 conversation, I sit down with @EricSo168168, Co-Founder & Executive Chairman of @Helus_Pharma, to explore: • The rise of “next-generation” serotonergic agonists; • Why psychedelic biotech is moving beyond psilocybin alone; • The push for scalable neuroplasticity medicines; • PTSD, depression, addiction & veteran mental health; • FDA acceleration pathways and recent White House actions; • Whether psychedelic therapies can realistically become standard of care; We also discuss the broader evolution from counterculture psychedelics to mainstream pharmaceutical neuroscience - and the major scientific, regulatory, and commercial challenges still ahead. #Psychedelics #MentalHealth #Neuroscience #Biotech #Psychiatry #PsychedelicMedicine #Neuroplasticity #HelusPharma #PrecisionPsychiatry #DepressionTreatment @rxMedyn @rxmedynamics

For more than 30 years, small cell lung cancer remained one of the most aggressive and difficult-to-treat cancers - with very few meaningful advances for patients. But a new wave of therapies may finally be changing the landscape. In this @ProgressPotent1 episode, I’m joined by Dr. @acoxon_coxon, Vice President of R&D at @Amgen, to explore the science behind IMDELLTRA, bispecific T-cell engagers, and the emerging concept of induced proximity in oncology. We discuss: 🧬 Why small cell lung cancer has been so difficult to treat; ⚔️ How bispecific antibodies physically link T cells to cancer cells; 📊 The striking Phase III survival data behind IMDELLTRA; 🔬 Why DLL3 may become a major new target in oncology; 🚀 How induced proximity is reshaping the future of drug development; This is a fascinating look at how modern cancer therapies are evolving from simply blocking biology…to engineering entirely new biological interactions. #SmallCellLungCancer #CancerResearch #Immunotherapy #Biotech #Oncology #DrugDevelopment #Amgen #InducedProximity #BiTE #CancerBreakthrough @AmgenOncology @RealChemistry_

@elonmusk @TheChiefNerd For complex bio-manufacturing too - youtube.com/watch?v=ZG18Go…

@TheChiefNerd Space is the only way

🚨 JENSEN HUANG: “The amount of energy that we need for computing is probably 1,000x more than we currently have.”

@DrJulieTChen @BuckInstitute

What if the future of medicine isn’t about treating disease after symptoms appear - but identifying risk years or even decades earlier?🩺🩻⚕️ In this @ProgressPotent1 conversation, I sit down with Dr. @DrJulieTChen MD - Chief Medical Officer of Radence and Sidestep Health AI - to explore the emerging world of “disease interception.” We discuss how medicine is shifting from reactive care toward: • ❤️early detection of cardiovascular, metabolic, neurodegenerative, and cancer risk; • 🩸continuous health monitoring and longitudinal biomarkers; • 🤖AI-driven interpretation of complex health data; • 🧬precision prevention and personalized health trajectories; • 🌱and the broader goal of extending healthspan - not just lifespan; Dr. Chen brings a uniquely grounded perspective shaped by years across academic research, integrative medicine, precision health, and the rapidly evolving longevity field. This was a thoughtful discussion about where the science of healthy aging is actually heading - and how the next generation of medicine may focus less on “anti-aging” and more on preserving function, resilience, and quality of life for as long as possible. Watch now - youtube.com/watch?v=BEF6HU… #Longevity #Healthspan #PreventiveMedicine #PrecisionMedicine #HealthyAging #DiseaseInterception #AIHealthcare #FutureOfMedicine #AgingResearch #Biotech @FINNPartners @FPIPR @RACapitalMgmt

For more than 30 years, small cell lung cancer remained one of the most aggressive and difficult-to-treat cancers - with very few meaningful advances for patients. But a new wave of therapies may finally be changing the landscape. In this @ProgressPotent1 episode, I’m joined by Dr. @acoxon_coxon, Vice President of R&D at @Amgen, to explore the science behind IMDELLTRA, bispecific T-cell engagers, and the emerging concept of induced proximity in oncology. We discuss: 🧬 Why small cell lung cancer has been so difficult to treat; ⚔️ How bispecific antibodies physically link T cells to cancer cells; 📊 The striking Phase III survival data behind IMDELLTRA; 🔬 Why DLL3 may become a major new target in oncology; 🚀 How induced proximity is reshaping the future of drug development; This is a fascinating look at how modern cancer therapies are evolving from simply blocking biology…to engineering entirely new biological interactions. Watch now - youtube.com/watch?v=tYmAw_… #SmallCellLungCancer #CancerResearch #Immunotherapy #Biotech #Oncology #DrugDevelopment #Amgen #InducedProximity #BiTE #CancerBreakthrough @AmgenOncology @RealChemistry_

Psychedelic medicine has entered an entirely new era. 🧠🚀 What was once considered fringe science is now at the center of FDA discussions, White House policy initiatives, veteran mental health programs, and a rapidly growing biotech industry focused on neuroplasticity and precision psychiatry. In this @ProgressPotent1 conversation, I sit down with @EricSo168168, Co-Founder & Executive Chairman of @Helus_Pharma, to explore: • The rise of “next-generation” serotonergic agonists; • Why psychedelic biotech is moving beyond psilocybin alone; • The push for scalable neuroplasticity medicines; • PTSD, depression, addiction & veteran mental health; • FDA acceleration pathways and recent White House actions; • Whether psychedelic therapies can realistically become standard of care; We also discuss the broader evolution from counterculture psychedelics to mainstream pharmaceutical neuroscience - and the major scientific, regulatory, and commercial challenges still ahead. Watch now - youtube.com/watch?v=rVyslb… #Psychedelics #MentalHealth #Neuroscience #Biotech #Psychiatry #PsychedelicMedicine #Neuroplasticity #HelusPharma #PrecisionPsychiatry #DepressionTreatment @rxMedyn @rxmedynamics

In a recent episode of @ProgressPotent1, our CEO Josef Freundorfer joined @irat1onal to discuss how Nuclea is rethinking the future of nuclear energy to meet growing global energy needs. 🔗 youtube.com/watch?v=EzDPo7…

What if the most powerful cancer drugs of the future can only be manufactured in space? That’s not science fiction anymore. In this fascinating episode of @ProgressPotent1, I sit down with Dr. Katie King - @KKingSpace - CEO & Co-Founder of @BioOrbitSpace - to explore the rapidly emerging world of “space pharma,” where microgravity may fundamentally change how we develop and manufacture medicines. We discuss: 🚀 Why pharmaceutical companies are beginning to look beyond Earth; 🧬 How microgravity changes crystal formation, biologics, and drug behavior; 💉 The possibility of cancer therapies impossible to manufacture on Earth; 🧠 Space as a laboratory for accelerated aging and degeneration research; 🏭 The future of orbital pharmaceutical factories; 🌍 How UK-U.S. collaboration is shaping the next biotech frontier; Dr. King’s company, BioOrbit, is pioneering autonomous pharmaceutical manufacturing systems for orbit - with missions already launched and more on the horizon. This conversation goes far beyond space exploration. It explores how removing gravity itself may unlock entirely new classes of medicine, materials, and biological systems. The future of biotech may not just be AI-powered… It may also be off-world. #SpacePharma #BioOrbit #KatieKing #Biotech #CancerResearch #Microgravity #SpaceMedicine #FutureOfMedicine #Longevity #ISS #Innovation #DeepTech #OrbitalManufacturing @FINNPartners

What if the most powerful cancer drugs of the future can only be manufactured in space? That’s not science fiction anymore. In this fascinating episode of @ProgressPotent1, I sit down with Dr. Katie King - @KKingSpace - CEO & Co-Founder of @BioOrbitSpace - to explore the rapidly emerging world of “space pharma,” where microgravity may fundamentally change how we develop and manufacture medicines. We discuss: 🚀 Why pharmaceutical companies are beginning to look beyond Earth; 🧬 How microgravity changes crystal formation, biologics, and drug behavior; 💉 The possibility of cancer therapies impossible to manufacture on Earth; 🧠 Space as a laboratory for accelerated aging and degeneration research; 🏭 The future of orbital pharmaceutical factories; 🌍 How UK-U.S. collaboration is shaping the next biotech frontier; Dr. King’s company, BioOrbit, is pioneering autonomous pharmaceutical manufacturing systems for orbit - with missions already launched and more on the horizon. This conversation goes far beyond space exploration. It explores how removing gravity itself may unlock entirely new classes of medicine, materials, and biological systems. The future of biotech may not just be AI-powered… It may also be off-world. Watch now - youtube.com/watch?v=ZG18Go… #SpacePharma #BioOrbit #KatieKing #Biotech #CancerResearch #Microgravity #SpaceMedicine #FutureOfMedicine #Longevity #ISS #Innovation #DeepTech #OrbitalManufacturing @FINNPartners

What is excessive screen time 📱 really doing to our brains, sleep, metabolism, attention spans, relationships, and mental health?🧠 In this powerful @ProgressPotent1 conversation, I sit down with Dr. Nidhi Gupta, MD - @nidhiguptatweet - pediatric endocrinologist, TEDx speaker, Founder of the Phreedom Foundation, and author of Calm the Noise - to explore the growing science of digital overuse and smartphone addiction. We discuss: • The neuroscience of dopamine-driven device habits; • How smartphones impact children vs. adults; • Sleep disruption, obesity, anxiety, burnout & fragmented attention; • Why healthcare professionals are especially vulnerable; • The hidden cost of constant notifications; • Practical strategies to reclaim focus, presence & real-world connection; Dr. Gupta’s work bridges pediatric endocrinology, neuroscience, behavioral health, and digital wellness - offering both scientific insight and actionable tools for navigating modern life more intentionally. An essential conversation for parents, professionals, educators, healthcare workers, and anyone who has ever felt unable to put their phone down. #DigitalWellness #ScreenAddiction #CalmTheNoise #BrainHealth #MentalHealth #SleepHealth #AttentionEconomy #DigitalDetox #Healthspan #Neuroscience @RPRFirm

What is excessive screen time 📱 really doing to our brains, sleep, metabolism, attention spans, relationships, and mental health?🧠 In this powerful @ProgressPotent1 conversation, I sit down with Dr. Nidhi Gupta, MD - @nidhiguptatweet - pediatric endocrinologist, TEDx speaker, Founder of the Phreedom Foundation, and author of Calm the Noise - to explore the growing science of digital overuse and smartphone addiction. We discuss: • The neuroscience of dopamine-driven device habits; • How smartphones impact children vs. adults; • Sleep disruption, obesity, anxiety, burnout & fragmented attention; • Why healthcare professionals are especially vulnerable; • The hidden cost of constant notifications; • Practical strategies to reclaim focus, presence & real-world connection; Dr. Gupta’s work bridges pediatric endocrinology, neuroscience, behavioral health, and digital wellness - offering both scientific insight and actionable tools for navigating modern life more intentionally. An essential conversation for parents, professionals, educators, healthcare workers, and anyone who has ever felt unable to put their phone down. Episode link - youtube.com/watch?v=ASxsbQ… #DigitalWellness #ScreenAddiction #CalmTheNoise #BrainHealth #MentalHealth #SleepHealth #AttentionEconomy #DigitalDetox #Healthspan #Neuroscience @RPRFirm

In the latest episode of @ProgressPotent1 our CEO, Josef Freundorfer, met with @irat1onal to discuss how Nuclea is working to redefine how nuclear energy is built, deployed, and scaled. Tune in to learn more about next-generation nuclear microreactors: youtube.com/watch?v=EzDPo7…

Every year, thousands of newborns suffer devastating brain injury caused by a lack of oxygen and blood flow during birth - a condition known as Hypoxic Ischemic Encephalopathy (HIE). It remains one of the leading causes of neonatal mortality and lifelong neurological disability worldwide. And despite decades of research…there are still no approved drug therapies specifically targeting the underlying inflammatory damage. But that may finally be starting to change. In the newest episode of @ProgressPotent1, I sit down with Dr. Howard Berman, CEO of @ReAltaLS, to discuss a fascinating new therapeutic approach centered around pegtarazimod - a virus-derived peptide designed to target two of the most upstream drivers of inflammatory injury: the complement system and neutrophil-mediated inflammation. Recently backed by a $40 million financing round, ReAlta is advancing its Phase 2 STAR trial in newborns with HIE, aiming to become the first company to successfully develop a targeted drug therapy for this devastating condition. We explore: 🧠 What actually happens biologically during HIE; 🧬 Why past therapies have struggled; ❄️ The limits of therapeutic hypothermia; 🦠 How a GI virus inspired an entirely new treatment strategy; 🔬 The science behind complement and neutrophil modulation; 👶 What success could mean for newborns, families, and NICU medicine worldwide; This is a powerful conversation about neuroscience, immunology, translational medicine, and the future of neonatal care. #NeonatalCare #HIE #Biotech #Neuroscience #NICU #DrugDevelopment #Immunology #ClinicalTrials #MedicalInnovation #HealthcareInnovation #RareDisease #BrainInjury #LifeSciences #FutureOfMedicine @russopartners

What does homelessness actually look like in America today? 🇺🇸🏡 Not the stereotypes. Not the politics. Not the headlines. The real human stories. In this powerful episode of @ProgressPotent1, I’m joined by @DWhitehead2020, Executive Director of @NationalHomeles, and award-winning filmmaker @valeriozanoli, director of the documentary HOMELESS. We dive deep into: ▪️ Why homelessness in America is surging; ▪️ The myths society still gets wrong; ▪️ Housing First vs. Treatment-First policy battles; ▪️ Life inside the tunnels beneath Las Vegas; ▪️ The intersection of housing, addiction, mental health, and poverty; ▪️ How storytelling can drive real-world change; ▪️ What most people never see about the unhoused experience; At a time when more than 750,000 Americans are experiencing homelessness, this conversation goes beyond statistics and politics to ask a deeper question: How did we get here - and what kind of society do we want to become? This is one of the most emotional, eye-opening, and important conversations we’ve had on the show. #Homelessness #HousingCrisis #EndHomelessness #SocialImpact #DocumentaryFilm #HousingFirst #AffordableHousing #MentalHealthAwareness #EconomicInequality #LasVegas #UrbanCrisis #HumanStories #SocialJustice #PublicPolicy #StorytellingForChange @Buffalo8Pro

For decades, North America’s best chefs have relied on imported European chocolate - despite long lead times, inconsistent supply, and limited flexibility. 🍫 But what if chocolate were designed by chefs, for chefs…and produced closer to the kitchens that actually use it? In this episode of @ProgressPotent1, I sit down with Brandon Olsen and Michael Held, co-founders of As We Do Chocolate Company, to explore how they’re rebuilding the chocolate supply chain from the ground up. We get into: - Why “one-size-fits-all” chocolate doesn’t work in professional kitchens; - What it means to customize chocolate at scale; - The hidden fragility in today’s global food supply chains; - And why this might be less about chocolate…and more about infrastructure; This is a fascinating look at how craft, manufacturing, and supply chain innovation are converging in unexpected ways. #FoodInnovation #SupplyChain #FoodTech #HospitalityIndustry #Entrepreneurship #FutureOfFood

Microreactor Revolution: Nuclear Power Goes Small, Mobile, and Off-Grid ⚛️ What if you could deploy a nuclear power plant like a shipping container…and run it for years without refueling? Not science fiction. Engineering in progress. In our latest episode of @ProgressPotent1, I sat down with Josef Freundorfer, CEO of @Nuclea_Energy, to explore how microreactors could redefine where - and how - we generate power. Josef brings hands-on experience from Bruce Power and Candu Energy, and is now leading development of the Morpheus Reactor: → Lead-cooled → Graphite-moderated → Designed for the hardest environments on Earth Think: • Remote communities • Mining operations • Military bases • AI data centers Places where diesel dominates - and power is expensive, unreliable, or both. ⚡ In this conversation, we get into: • What actually makes microreactors viable now; • Why HALEU fuel could be the bottleneck to scaling; • Whether nuclear can power the next wave of AI infrastructure; • And what it really takes to deliver clean, firm power anywhere; Zero-carbon. High reliability. No grid required. #NuclearEnergy #Microreactors #AdvancedNuclear #CleanEnergy #EnergySecurity #ClimateTech #OffGridPower #DataCenters #HALEU #EnergyTransition @CoreIR_

Every year, thousands of newborns suffer devastating brain injury caused by a lack of oxygen and blood flow during birth - a condition known as Hypoxic Ischemic Encephalopathy (HIE). It remains one of the leading causes of neonatal mortality and lifelong neurological disability worldwide. And despite decades of research…there are still no approved drug therapies specifically targeting the underlying inflammatory damage. But that may finally be starting to change. In the newest episode of @ProgressPotent1, I sit down with Dr. Howard Berman, CEO of @ReAltaLS, to discuss a fascinating new therapeutic approach centered around pegtarazimod - a virus-derived peptide designed to target two of the most upstream drivers of inflammatory injury: the complement system and neutrophil-mediated inflammation. Recently backed by a $40 million financing round, ReAlta is advancing its Phase 2 STAR trial in newborns with HIE, aiming to become the first company to successfully develop a targeted drug therapy for this devastating condition. We explore: 🧠 What actually happens biologically during HIE; 🧬 Why past therapies have struggled; ❄️ The limits of therapeutic hypothermia; 🦠 How a GI virus inspired an entirely new treatment strategy; 🔬 The science behind complement and neutrophil modulation; 👶 What success could mean for newborns, families, and NICU medicine worldwide; This is a powerful conversation about neuroscience, immunology, translational medicine, and the future of neonatal care. Watch now - youtube.com/watch?v=I9a7y6… #NeonatalCare #HIE #Biotech #Neuroscience #NICU #DrugDevelopment #Immunology #ClinicalTrials #MedicalInnovation #HealthcareInnovation #RareDisease #BrainInjury #LifeSciences #FutureOfMedicine @russopartners

@elonmusk These guys are doing pretty cool work too 😉-youtube.com/watch?v=n5vCjb…

Neuralink progress