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Richard Roth
109 posts
Richard Roth
@R_H_Roth
🇩🇪🧠 Postdoc in Ding lab @StanfordMed · motor circuits | synaptic plasticity | in vivo imaging · PhD in @rhuganir lab @HopkinsNeuro, BSc @TU_Muenchen · he/him
Katılım Haziran 2019
265 Takip Edilen364 Takipçiler
Richard Roth retweetledi
Why are some neurons more selective than others? We report now in @Nature how calcium permeable-AMPA receptors in PV neurons make them less selective to sensory features nature.com/articles/s4158… Long live the geniuses behind this🧠🔍juhyun.kim @thainmueller @rhuganir
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Richard Roth retweetledi
Super-excited to reveal our latest fluorescent voltage indicator, ASAP5, now online @NeuroCellPress!
ASAP5 features higher responsivity and kinetics, allowing detection of single synaptic transmission events.
The link gives free access until 2024.11.09:
authors.elsevier.com/a/1joYd3BtfH9B…
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Richard Roth retweetledi
Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye!
The dye is tartrazine, used in Doritos!
science.org/doi/10.1126/sc…
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Check out this beautiful study from @Dr_Oligo, now online @Nature, demonstrating a crucial role for oligodendrocytes and myelin in regulating structural and functional neuronal plasticity! Happy to have contributed.
nature.com/articles/s4158…
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@R_H_Roth @NeuroCellPress Looks very nice, but I have to point out mice have hands, not paws (I’ve gotten it wrong before too).
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Very happy to share our latest review @NeuroCellPress on plasticity within cortico-basal ganglia circuitry in motor learning! It was fun to take stock of all the progress we've collectively made, but there are still many exciting directions ahead.
doi.org/10.1016/j.neur…
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Richard Roth retweetledi
Thrilled to share our preprint reporting the discovery of a previously unrecognized population of LepR-expressing fast-acting satiety neurons in the hypothalamus ARC. These neurons directly inhibit AGRP neurons, providing a crucial counterbalance. biorxiv.org/content/10.110…
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Myelin as a master regulator of neuronal plasticity? 🧐
Check out this new study from @Dr_Oligo !
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Richard Roth retweetledi
@rhuganir and I are delighted to share our new preprint on calcium permeable-AMPA receptors in PV interneurons! Why are there so many CP-AMPARs in this particular GABAergic cell-type? Why are PV interneurons typically lower in feature selectivity? Read on!
twitter.com/biorxiv_neursc…
bioRxiv Neuroscience@biorxiv_neursci
Calcium-permeable AMPA receptors govern PV neuron feature selectivity biorxiv.org/cgi/content/sh… #biorxiv_neursci
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Richard Roth retweetledi
Excited to share our work out today @Nature nature.com/articles/s4158…
Big congrats to authors Lei Ma, Julian Day-Cooney, @mmuunniiaakk, Omar Benavides, Maozhen Qin. Great collaborations with @BJunDing and Tianyi Mao labs. @VollumInstitute @OHSUNews
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Happy to share our latest study from the @BJunDing lab recently published in @NeuroCellPress! We show that motor learning selectively induces synaptic plasticity at inputs and outputs of behavior-relevant neurons in motor cortex.
cell.com/neuron/fulltex…
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Very nice work! Big congrats, Richard!
Richard Roth@R_H_Roth
Happy to share our latest study from the @BJunDing lab recently published in @NeuroCellPress! We show that motor learning selectively induces synaptic plasticity at inputs and outputs of behavior-relevant neurons in motor cortex. cell.com/neuron/fulltex…
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I highly recommend the Huganir lab to anyone interested in neuroscience research! Fantastic mentorship and supportive scientific environment! I had a wonderful experience in the lab when I was there.
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Also thanks @StanfordBrain for making this beautiful video summary of our work! Check out the video here:
twitter.com/StanfordBrain/…
Wu Tsai Neurosciences Institute@StanfordBrain
As mice learned a tricky new movement, Jun Ding (@bjunding) & #WuTsaiNeuro colleagues saw motor circuits across the #brain rewire. The team aims to study how disorders like #Parkinson's impact such memories. Watch the video: stanford.io/3RB2cNm @Stanford_Neuro @StanfordNsurg
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I am especially grateful to our wonderful team Fuu-Jiun Hwang, @yuweiwu_imb, @YueSunNeuro, Destany Kwon, and Yu Liu!
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Richard Roth retweetledi
I’m excited to share a novel tool, Cal-ID, which performs calcium-dependent proximity labeling to capture molecular events of calcium signaling! We show that Cal-ID can label proteins near active calcium signaling sites in HEK293T cells & mouse neurons.
biorxiv.org/content/10.110…
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