Tim Gamache

Excited to share our new preprint on #SYNGAP1 that shows how its enzymatic and structural role can be dissociated! The GAP activity is essential in increasing intrinsic excitability but does not contribute to the seizure protection SynGAP is important for. biorxiv.org/content/10.110…

@Han_L_Tan @Nature Congrats Han!!

Thrilled to share our paper online @Nature (on my birthday)! We've identified a new population of LepR neurons (BNC2) in the hypothalamus ARC that acutely suppresses appetite by directly inhibiting AGRP neurons, decoding the missing LepR GABAergic neurons. nature.com/articles/s4158…

@Ih_current @Nature @thainmueller @rhuganir Congrats, Ingie and team!! Breathtaking work!

Why are some neurons more selective than others? We report now in @Nature how calcium permeable-AMPA receptors in PV neurons make them less selective to sensory features nature.com/articles/s4158… Long live the geniuses behind this🧠🔍juhyun.kim @thainmueller @rhuganir

@EManiax Beautiful space! Congrats!

A new chapter of the Watanabe lab. In the last 2 weeks, 2 papers accepted, 2 new grants awarded, and a new lab space completed! We can finally all be in the same space!! More exciting science to come!!

@wd_hale @rhuganir @cryoET @frettinglab @Cuau_Ulises @alejandraaaaa_r Super cool work, Dylan!!

Happy to say today in Science, we show synaptic RasGAP protein SYNGAP1 regulates the synaptic plasticity and cognition independently of its catalytic activity. science.org/doi/10.1126/sc… This is the culmination of multi-year hard work alongside my colleagues. Special thanks to @rhuganir, @LizEGerber, @RajkovichKacey, @trgamache, @HaitnTran, @theBianLiu, @QianwenZhu2, @Ih_current.

I’ve had an immeasurable amount of support from so many people, to whom I owe everything for making this possible for me. I’m beyond excited to begin writing this next chapter! (3/3)

I’m so fortunate to have the opportunity to pursue my JD while simultaneously continuing to work as a patent agent in a field I love. I will always be a scientist, and I’m excited to open some new doors, make new discoveries, and help new people. (2/3)

It’s surreal to say this, but I will officially be attending Northeastern University School of Law (@NUSL) in the Fall to pursue my law degree! (1/3)

@rodriguez_lion Congrats Lionel!!!

My first ever first author paper has been accepted!!!!!!!!!!! finally 😭🥳❤️🍾🎉

@EManiax @TheValleeFdn Congrats Shigeki!

I am delighted to be a part of the community! Thank @TheValleeFdn for funding our work!

@R_H_Roth @BJunDing @NeuroCellPress Congrats Richard! Beautiful work!

Happy to share our latest study from the @BJunDing lab recently published in @NeuroCellPress! We show that motor learning selectively induces synaptic plasticity at inputs and outputs of behavior-relevant neurons in motor cortex. cell.com/neuron/fulltex…

@aneneim @PhiloNeuroSci What is going on??? So sorry to hear this…

@RajkovichKacey Welcome to IP law, K!!!

2018 Breakthrough Prize Winner & Tau discoverer, Dr. Don Cleveland, to speak TOMORROW Wed Nov 11 @ NOON EST for our GW Julius Axelrod Brain Series. Please join us! Link to talk: lnkd.in/eQebU_S @gwneurology @GWSMHS @UCSDNeuro @UCSDHealth @AANMember #medicine #Neurology

@djottenheimer @JanakLab @ScienceAdvances Congrats David!

Need a distraction? The culmination of my @JanakLab dissertation is out today in @ScienceAdvances! We found that ventral pallidum neurons track rats’ preferences for water and sucrose as they progress from thirsty to sated, and can influence their choices. advances.sciencemag.org/content/6/45/e…

Happy #Halloween from Hubble! 💀 These interacting galaxies create a creepy “face” in space. There’s no sound in space, but this scary sonification of Hubble's image will send shivers down your spine... More: go.nasa.gov/3eeJAQ0 #NASAHalloween Credit: @system_sounds

@BostonSymphony Trombones getting the “quiet” hand at 1:23 - some things never change :). Lovely as always!

On Wednesday, we were overjoyed to perform together again on the Symphony Hall stage, for the first time since March! Please enjoy this clip of Dvořák's Symphony No. 9 "From the New World," led by former BSO Associate Conductor Ken-David Masur.

@Dr_Oligo @AliceBLee @HopkinsNeuro @jhneurostudents Thanks so much, Wendy!! ❤️ And congrats, Alice!!