Ravoke

There is some misinformation in this @sciam article👇 1- “Extensive research has shown that the snippet of mRNA enters cells but not the cell nucleus” — there is no nucleus during mitosis of dividing cells and so cytoplasmic material mixes with the chromosomes. 2- “mRNA is easily broken down by the body. Humans ingest mRNA all the time from the food we eat, but our digestive system deactivates it” — the mRNA vaccines use pseudouridine-modified mRNA to stabilize the RNA so it isn’t broken down easily. That was a breakthrough that won the Nobel Prize a few years ago. However, it also meant that with the mRNA vaccines, the dose, biodistribution, and persistence in the human body were unknown and have not yet controlled. 3- Data emerged for persistence of COVID mRNA vaccines for over 2 years, not a few hours or days as stated “the mRNA remains for hours or, at most, a few days before a specialized enzyme breaks it down.” 4- The COVID mRNA vaccine “side effects are short-lived and far less serious than an infection,” is inaccurate when one considers numerous side effects such as myocarditis, coagulopathy, neuro-inflammation among others. Post-vaccine syndrome and long-Covid have much in common. 5- “some evidence suggests having more side effects may be associated with a stronger immune response” is misleading as after 4 shots there is IgG4 class switching that has been associated with worse outcomes. For patients with cancer, COVID mRNA vaccination increases PD-L1 expression which is an immune evasion mechanism that is tumor-promoting. While there is some evidence that subsequent treatment with cancer immunotherapy holds promise, the underlying mechanism of synergy can be induced by other agents that actually have anti-tumor efficacy. mRNA vaccines on their own do not have anti-tumor efficacy and the increase in PD-L1 they cause in existing cancers is tumor promoting. 6- “mRNA vaccine technology can speed up vaccine development—as it did with the COVID vaccines” was true in a public health emergency. But corners were cut with a change in the manufacturing process between the original that was tested in clinical trials and what was rolled out globally. Impurities have been found with the use of Process 2 including DNA fragments and plasmid DNA that contains SV40 promoter/enhancer sequences. Assays of DNA contamination that were used have been shown to underestimate contamination due to RNA:DNA hybrids. There has not been informed consent or liability for mRNA vaccines despite much that has been reported. It is clear that individuals have varying risk towards any illness and so 6 years later, paying attention to individualized risk and personalized recommendations makes sense. More studies documenting forensic evidence in those with adverse outcomes is needed along with more basic research to further investigate disease mechanisms. I have written about the need for informed consent from the point of view of cancer risk. It doesn’t mean the risk is high or that anyone whose physician feels would benefit from a COVID mRNA vaccine shouldn’t get it and have it covered by insurance. I have also written with my colleague @KUPERWASSERLAB a review of COVID infection, COVID vaccines and cancer signals. There should be a balance in informing the public that I found lopsided in this article. @HHSGov @US_FDA @NIHDirector_Jay @DrMakaryFDA @SenRonJohnson @Kevin_McKernan @SabinehazanMD @MaryanneDemasi @danaparish @Jikkyleaks @P_McCulloughMD Why you should keep getting mRNA vaccines scientificamerican.com/article/how-do…