Wafik S. El-Deiry, MD, PhD, FACP

Books I have edited that may be of interest to those who study cancer. They are all available on Amazon.

As a private citizen, this morning I had the pleasure and honor to meet Xay Khamsyvoravong @XayForRI who has served as mayor of Newport, Rhode Island and is currently running for Rhode Island Lieutenant Governor. His personal story is truly inspiring as are his ideas for making a difference here in RI.

Robotics and AI Institute’s robot pulling off impressive jumps, flips, and balance control

Regarding dissolving the ACIP- I have now been told that this was a miscommunication, and in fact the decision about how to proceed has not been made, and dissolving and reforming remains one of options being considered.

This reflects how science has been packaged and evaluated over the past two decades. In the 2000s figure preparation software such as PowerPoint and Illustrator became straightforward to use. By the early 2010s, high-impact journals came to associate dense, elaborate figures (i.e. the exhibits of a scientific study) with rigor and depth. The implicit assumption was that more panels and more data reflected more thorough and careful work. At the same time, the editorial decision on whether to proceed to peer review was made by individuals not deeply embedded in the specific science, relying more on visual presentation and the perceived completeness of the data. The aesthetics of the figure panels became a proxy for scientific thoroughness. In response, scientists adapted. Figures became more complex, more densely populated, and more expansive in scope. This gave the appearance of rigor independent of whether the additional data materially clarified the central questions of the study. Reviewers were tasked with evaluating these large and complex datasets under significant time constraints, typically within a few days and without compensation, while managing substantial professional responsibilities. Under these conditions, it is impossible to systematically interrogate every component of a multi-panel figure. There is also a reluctance to question whether key elements of a study are missing if there is a possibility they are included somewhere within the large amount of presented data. The result is a publication system in which the presentation of large volumes of data in complex figure formats can facilitate publication in high-profile journals, often with limited connection to the underlying clarity, coherence, or quality of the science itself.

Thymic health and immunotherapy outcomes in patients with cancer nature.com/articles/s4158…

Prodrug-tethered lipid nanoparticles for synergistic messenger RNA cancer immunotherapy nature.com/articles/s4156…

National survey of NIH-funded researchers shows precarious state of U.S. science — 'This is like the Titanic' statnews.com/2026/03/19/nih…

Researchers surveyed by STAT detail the toll of grant cuts: labs shutting down, data unanalyzed statnews.com/2026/03/19/nih…

Outstanding choice. Congratulations to @DrRobWinn @FoxChaseCancer Temple Health Appoints Robert A. Winn, MD, as Cancer Center Director for Fox Chase Cancer Center foxchase.org/news/temple-he…

Outstanding Pathology Grand Rounds today by Trista North, PhD, Co-Director, Developmental and Regenerative Biology Program, Professor of Pediatrics, @harvardmed, Stem Cell Program, Division of Hematology/Oncology, @BostonChildrens Hospital who spoke about “Microenvironmental Regulation of Hematopoietic Stem Cell Formation and Function in the Vertebrate Embryo” Very interesting results about the role of ROS, mitophagy, Bnip3l, EZH1 and EZH2 with use of elegant zebrafish models. @BrownPathology @BrownPathRes @BrownUPathoGP @BrownMedicine @NorthTrista @ClubDanio @rwsobol @SenduraiMani @SeanLawler20

@TempleHealth today announced the appointment of Robert A. Winn, MD, as the next Cancer Center Director for Fox Chase, marking a defining moment that will shape the future of one of the nation’s leading @theNCI designated Comprehensive Cancer Centers: bit.ly/47azyMA

Real pleasure to chair the WIN MTB along with @weldeiry and try to help patients across the globe

Outstanding international @WIN_Consortium MTB with discussion of difficult cases presented today by @SewantiLimaye of signet cell gastric cancer, adenoid cystic cancer and intrahepatic Cholangiocarcinoma with various driver molecular alterations that may be amenable to targeted therapy combinations including radionuclide therapy @Dr_R_Kurzrock @WIN_Consortium Today’s participants from US, Canada, India, Spain, Australia and China among others.

Great meeting of the @WIN_Consortium Thoracic Cancer Disease Committee to discuss current membership, innovative concepts for thoracic Precision Oncology clinical trials, opportunities for collaborative grant funding and pharmaceutical collaboration @HinaKhanMD @DrRoyHerbstYale @bcarneiro7 @DCarboneMD @NaglaAKarimMD

@LabWaggoner Not restricted by me.

@LabWaggoner It was restricted at the time.