Roca Verde

🚨 KETO-CTA: A Teachable Moment in Scientific Transparency - - - What happens when a highly publicized study FAILS to report its primary outcome? The KETO-CTA study, designed to evaluate the impact of diet-induced hypercholesterolemia on coronary plaque progression, has sparked interest—and concern. Despite preregistering % change in non-calcified plaque volume (ΔNCPV) as the primary endpoint (see image below), the investigators did not report this outcome directly in the manuscript. Instead, results appeared later...in a social media meme. 🔍 Why it matters: Non-calcified plaque progression is not a trivial metric—it’s the most relevant measure of early atherosclerotic risk. In KETO-CTA, ΔNCPV was +18.8 mm³ in one year (according to the lead investigator--see below), a rate typically associated with much higher-risk cohorts (e.g., familial hypercholesterolemia or diabetes). This was a study of supposedly "low-risk" individuals. 📉 Additional limitations include: 🔹 Short follow-up (1 year): Too brief to reliably detect meaningful progression in low-risk populations. Most longitudinal plaque imaging studies span 3–6 years. 🔹 Lack of control group: No comparator arm to contextualize imaging findings or isolate effects of diet-induced hypercholesterolemia. 🔹 Historical controls misapplied: Cross-study comparisons without accounting for differences in baseline risk, imaging protocols, or statistical methods. 🧠 This isn’t just about one study. When primary outcomes vanish from manuscripts, it erodes trust. When clinical implications are downplayed, we risk misleading patients. The duty to report results transparently isn't optional—it’s foundational to scientific integrity. Let’s be clear: ketogenic diets may offer benefits in select cases. But studies evaluating their cardiometabolic effects must be held to the same rigorous standards applied to all clinical research. In this case, the investigators appear to have fallen short—and possibly engaged in selective or misleading reporting to obscure unfavorable outcomes. 📣 We need better, not louder. We need data, not dodges. Most importantly, we need to treat scientific integrity as non-negotiable. STUDY: jacc.org/doi/10.1016/j.… #EvidenceBasedMedicine #KetoCTA #Cardiology #ResearchEthics #ScientificIntegrity #PreventiveCardiology

Highly paid FT editors advise UK govt to cut welfare spending; hurt the disabled, sick. poor, old. Silence on redistribution of wealth; higher wages, reducing corporate welfare, ending tax perks of the rich It is class war. archive.ph/eJcv3 ft.com/content/cd3624…

Amos Goldberg, Professor of Genocide Studies at The Hebrew University in Jerusalem "Yes, it is genocide. It's so difficult and painful to admit it, but we can no longer avoid this conclusion. Jewish history will henceforth be stained" Is there anyone more qualified and unbiased?

Well..

Piers Morgan and his hacking phones story.

AOC: We stand here two days after president Trump gave unconditional pardons to violent criminals and these are the people who want us to believe they're trying to “keep criminals off the streets” when they are opening the floodgates.

Fluoride is a salt form of fluorine (13th most abundant element on Earth, naturally found in water). It reinforces bones by increasing bone cell proliferation. It is completely harmless at concentrations in fluoridated water (≈ 0.7 mg/L) RFK Jr is not educated in biosciences

Israel Is Killing Civilians In Gaza On Purpose, And It’s Not Even Debatable Just so we’re all clear, it is a fully established fact that the IDF is directly, deliberately killing civilians in Gaza. There was a time in the early days of the genocide when this could be disputed, but that is no longer true. The facts are in and the case is closed. It’s happening. Israeli soldiers are telling the press that they’ve been knowingly killing civilians and then falsely categorizing them as terrorists afterward. Countless doctors have testified to routinely encountering dead and wounded children who’ve been shot in the head by Israeli snipers. Israeli media reports have revealed that the IDF is intentionally targeting civilian infrastructure and using AI systems to specifically target suspected Hamas members when they are at home with their families instead of out on the battlefield. The debate is over. The “human shields” argument has been completely, thoroughly debunked. If you still deny that this is happening, its because your worldview is so false that it requires you to deny facts and reality. Reading by Tim Foley.

As genocide worsens in Palestine and mosques and churches destroyed, PM Albanese faces moral & legal crossroad Posted by Dr Daud Batchelor ‘Australian Prime Minister Albanese calls culprits of Melbourne’s synagogue fire, ‘Terrorists,’ but ignores destruction by Israeli Defense Forces (IDF) of 814 mosques and three churches in Gaza.’ And included in the potential consequences of popping over to participate in the genocide: ‘.. under Australian Citizenship Act 2007, Australian dual citizens may lose citizenship if engaged in actions inconsistent with international law….. Allowing Australians serve overseas in the IDF, sends a dangerous message that Australia tolerates war crimes. PM Albanese faces a clear choice. He can uphold Australia’s international obligations, or he can remain silent, becoming complicit in one of the gravest war crimes in history. The world is watching and history will judge his response.’ amust.com.au/2024/12/as-gen…

Israel. Is. Killing. Civilians. Including. Babies. And. Children. Deliberately. It. Is. Not. A. War. It. Is. GENOCIDE. And. The. West. Is. Enabling. The. GENOCIDE.

Israel building settlements in Gaza is like putting a luxury housing estate in the grounds of Auschwitz I can't imagine a nation with less of a moral compass than Israel, absolutely disgusting 🐝 #auspol

@TheNational do I get a prize?

If you're like me, you've been waiting for analysis from @sfardm, Israel's foremost international human rights lawyer, on the ICC warrants for Netanyahu & Gallant. As ever, Michael doesn't disappoint. The following is from Michael's FB page, translated from the original Hebrew:

@terrychristian This is a brilliant explanation of the problem and why farmers should WELCOME inheritance tax. youtube.com/watch?v=s9J0Gp…

Wealth growth since 1970 Average - 8% Top 10% - 85% Top 1% - 320% Top 0.01% - 4000% Billionaires - 32000% Can you see the problem?

@bethrielly @helensclegel @out_of_lives @bristolnoborder @SpycopsInfo @mehdirhasan @jeremycorbyn @HackneyAbbott @Harryslaststand @owenjonesjourno @DavidDavisMP @GreenJennyJones Undercover police officers have infiltrated UK activist networks & forged relationships with individual women for over 50 years 140 undercover officers spied on more than 1,000 political groups Three women targeted by #spycops reconstruct what happened theguardian.com/uk-news/video/…