Ruben QC

🔬Honored for the opportunity to contribute this viewpoint @NatMetabolism where we discuss on Mitochondrial Transfer; its evidences, challenges and opportunities, with plenty of room for exciting research yet to come! rdcu.be/eCFRX

Simultaneous spatial transcriptomics and morphology profiling as tools to explore how microglia change with age | Nature Aging nature.com/articles/s4358…

#Throwback COMMENT | @nutsci, L Golzarri-Arroyo & DB Allison A brief guide to statistical analysis of grouped data in preclinical research nature.com/articles/s4225…

⚠️Cómo se transfieren mitocondrias las células del sistema nervioso y los gliomas? 🧠 Si quieres investigarlo, únete a nosotros! 🔬 Solicita la JAEINT26_EX_0587!

@LMPrida Congratulations, Liset!!! 👏

Honored to receive the 2026 Suffrage Science Award for Life Sciences. A privilege to follow in the footsteps of Azahara Oliva and join this inspiring network. This recognition belongs to the amazing team I work with every day. suffragescience.com/post/2026-suff…

Optical clearing & time-lapse fluorescent imaging of Live mouse Brain (up to 800 μm of depth)🤯 SeeDB-Live is finally in peer-reviewed print (1.5 yr from Preprint)🥸 An acute olfactory bulb slice(P11) loaded with GCaMP6f (Ca2+ sensor) was imaged with #2PM at a depth of 150 μm during clearing with SeeDB-Live👹 @Shigenori774 @TakeshiImaiLab @naturemethods 2026 nature.com/articles/s4159…

Gut microbes signal the brain influencing age-associated memory and cognitive function in the experimental model @arcinstitute @Nature nature.com/articles/s4158…

This is how cells in your body move

Today in @Nature, the @ChristophThaiss & @MaayanLevyPhD labs trace age-related memory loss to the gastrointestinal tract & map the complete gut-to-brain pathway driving it. Targeting this pathway can reverse cognitive aging in mice. nature.com/articles/d4158…

In the latest issue! Meningeal blood vessel blockage enhances anti-glioblastoma immunity dlvr.it/TRMg3V

Researchers observed a marked decline in the number of oligodendrocyte progenitor cells during aging, notably within the subpopulation highly expressing Acss2, which encodes acetyl-CoA synthetase 2. 📘 @NatureAging 🔗 go.nature.com/4b3DvDJ

New online! Function and regulation of the mitochondrial stress response dlvr.it/TRKDQC

New @ScienceMagazine Engineering the brain's astrocytes to clear amyloid plaque! "CAR-A," in mouse model science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…

(1/5) How does glioblastoma maintain its immense heterogeneity? 🧠 Two new companion papers from the Bhaduri Lab @UCLA now on @bioRxiv offer a lineage-resolved view of GBM hierarchies. Let’s dive in! 🧵👇 biorxiv.org/content/10.648… biorxiv.org/content/10.110…

Great resource! The authors built an enhancer-AAV library that targets major basal ganglia cell types across mouse and macaque, filling a real gap for studying movement and psychiatric circuits beyond rodents. biorxiv.org/content/10.648…

Rubén Quintana rer-biomed.csic.es/grupos/determi… Aixa Morales rer-biomed.csic.es/grupos/control… Fernando de Castro rer-biomed.csic.es/grupos/grupo-d… Mariano Carrión rer-biomed.csic.es/grupos/614/ Pablo Hernansanz rer-biomed.csic.es/grupos/fosfori… Monica Chagoyen rer-biomed.csic.es/grupos/biomedi…

La resolución microscópica 🔬acaba de dar un salto gigante! 🧬✨ Se ha presentado Seq-Scope-eXpanded, una tecnología que lleva la ómica espacial más allá de los límites ópticos convencionales. 🔬🚀 🤯 Tradicionalmente, ver dónde se activan los #genes en un tejido dependía de la resolución de los microscopios. Con esta nueva técnica, los científicos pueden mapear la expresión genética a una escala subcelular sin precedentes, ¡permitiendo ver detalles que antes eran invisibles! 🔍💎 ​Este avance es clave para entender enfermedades como el cáncer 🎗️ o problemas del desarrollo, ya que permite ver exactamente qué ocurre dentro de cada célula y cómo se comunican con sus vecinas. ​¡El futuro de la medicina personalizada y la biología celular ya está aquí! 🧬🌍 ​#Biotech #Genomics #SpatialOmics #ScienceNews #Innovation #CellBiology #SeqScope #NatureCommunications #Genética #investigacion #Ciencia ​🔗 👇 doi.org/10.1038/s41467…

El futuro de la #Neurociencia empieza en las aulas. Hoy en la #FeriaDeEmpleo de la Facultad de Ciencias de la @UAHes hemos invitado a los estudiantes a formar parte del CNC y del Ci2A. Biomedicina, física, informática, computación, IA... ¡Únete al equipo! 📩contacto@cajal.csic.es

🧠💻 Are you a Data Engineer passionate about AI and neuroscience? We’re looking for experts to develop robust data processing pipelines, enable multimodal data integration, and support AI-based tools within our Multimodal Brain Mapping platform. 📩 contact@cajal.csic.es

Review @NatRevDrugDisc @Denalitx Therapeutic targeting of neuroimmune mechanisms in neurodegeneration nature.com/articles/s4157…

Sensory neurons have emerged as unexpected contributors to cancer progression, helping to drive tumour growth and invasion go.nature.com/4rAbevn