Marc Erhardt

Interested in anti-bacteriophage defense systems? We have an open PhD position in cell biology of bacteria and bacteriophages: nature.com/naturecareers/…

Congratulations to first author @AritzRoa for his amazing work on how T4 delivers its genome and blocks other phages from injecting theirs 🥳 Check out his beautiful movie📽️ Thanks to all authors and collaborators MLNielsen and @AHarms485 tinyurl.com/2kvva646 #cryoEM #phage

#MicrobiologyMonday: The bacterial flagellum is built through a hierarchical assembly process and powered by a dynamic motor capable of astonishing speeds. What's new in our understanding of these complex nanomachines? Find out in #MMBRJournal: asm.social/2HB

A beautiful example of evolutionary innovation: Bacterial chemoreceptor was "reprogrammed" in pathogenic E. coli to control expression of flagellar genes instead of signalling through the chemotaxis pathway. embopress.org/doi/full/10.10…

@JorgStulke @NatureMicrobiol Thanks, Jörg 😀!

@NatureMicrobiol Congrats, @Salmo_Lab and all involved! Awesome work!

Out Now! The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation bit.ly/4nqcNe9 #Microbiology #Bacteria #Flagellum

"The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation" Now published @NatureMicrobiol 🥳! rdcu.be/eugWM

@AHarms485 Thanks a lot for your visit and the exciting seminar! It was great to have you here and I hope you had a safe trip back home!

New favorite writing spot at the beach of Cold Spring Harbor Laboratory 😙🌊

Cold Spring Harbor Laboratory - absolutely humbled by the beauty of this place and the ubiquitous spirit of the Delbrück "phage group" era 🧬🌊🦪

Exited to share our preprint on the structure of a Salmonella contractile injection system 🥳 Wonderful work by first author @Rooshanie Ejaz and @CloudyKielkopf, @freddie__martin, @HangryHobbit, @RebrovaEva, great collab with @Salmo_Lab @UCPH_CPR #cryoem shorturl.at/QHLpm

And here it is, the completed BASEL collection finally published as early access in @PLOSBiology - see the thread for more details. 🤗🧬🎣

@GitaNaseri @mpusp_pathogens @FraunhoferIPA Congrats 🎉!!

Together with Hannes Hinneburg, we have secured €1.3M funding for the MyPro project through #VolkswagenStiftung volkswagenstiftung.de, to develop mycelium-based sustainable materials using #synbio and advanced, scalable production processes @mpusp_pathogens and @FraunhoferIPA

Now published @PNASNews 🥳 Bacterial motility depends on a critical flagellum length and energy-optimized assembly | PNAS pnas.org/doi/10.1073/pn…

New #biorxiv preprint I'm quite excited about. We show that the #T3SS of the #flagellum secretes proteins at a rate of 10,000 amino acids per second, resulting in optimized flagellum growth and energy consumption. biorxiv.org/content/10.110…

Join us and @Salmo_Lab to explore phage-bacteria interactions, with a strong focus on microscopy techniques. Looking for a motivated PhD student! 🔬 Interested? Apply here 👉 [nature.com/naturecareers/…] 🔄 Please re-share to spread the word!

With @jrpenades, we challenged AI co-scientist @GoogleAI to generate hypotheses. In just 2 days, it recapitulated our unpublished, experimentally confirmed mechanism for how cf-PICIs spread between bacterial species! 🤯 @imperialcollege @FlemingCentre tinyurl.com/3byyaeh2

Our paper out @Nature: CARD domains mediate anti-phage defense in bacterial gasdermin systems CARDs are essential for caspase recruitment in inflammasome activation. We now find them in bacterial immune systems Congrats @TanaWein! Thanks Kranzusch lab! tinyurl.com/CA88DD

Internationales Forschungsteam beschreibt erstmals die Struktur und Funktionsweise des Zorya-Systems, eines hochspezialisierten antiviralen Schutzmechanismus gegen Bakterien nature.com/articles/s4158… @Salmo_Lab @__jphilipp Bild: Frederick J.O. Martin/ Universität Kopenhagen

🦠 Neues bakterielles #Immunsystem entschlüsselt: Ein internationales Forschungsteam um @Salmo_Lab & @__jphilipp der #HumboldtUni beschreibt nun erstmals die #Struktur und #Funktionsweise des Zorya-Systems in der Fachzeitschrift @Nature! Mehr Infos 👉 hu-berlin.de/de/pr/nachrich…

Thrilled to share that our collaborative work, led brilliantly by @HaidaiHu, is now published in @Nature! Huge thanks to the incredible @NMITaylorLab team - it was a joy to work with you. Grateful to @Salmo_Lab, @SimonJacksonNZ, and @AHarms485 for their invaluable contributions!

Our work describing the structure and mechanism of the Zorya anti-phage defense system is finally out @Nature! Led by @HaidaiHu and @__jphilipp in a wonderful collaboration with @NMITaylorLab, @SimonJacksonNZ, @AHarms485 et al.! nature.com/articles/s4158…