Sean Glass 🇺🇸 🇿🇦🇪🇺🇬🇧

3.1K posts

Sean Glass 🇺🇸 🇿🇦🇪🇺🇬🇧

Sean Glass 🇺🇸 🇿🇦🇪🇺🇬🇧

@Seanglass

Investor and Former Entrepreneur - investing at Evidenced

Katılım Ocak 2008
2.3K Takip Edilen2.3K Takipçiler
Bijan Salehizadeh
Looks like all incoming planes into DCA IAD BWI and RIC being diverted to RDU, PHL, and a few to JFK. Others returning to departure airports based on Flightradar. Gonna be a long night
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Bijan Salehizadeh
@Seanglass @StuartBlitz eesh. I'm 2 hours out of DCA still in flight. Nothing from captain yet. Expecting a diversion. Some flights are taking off from IAD last 15 min but DCA shut. I see no landing at IAD.
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Bijan Salehizadeh
@StuartBlitz Chemical smell at DC area traecon - apparently hazmat onsite and has been evacuated. Not good.
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Ben South
Ben South@bnj·
Introducing @variantui Enter an idea and get endless (beautiful) designs as you scroll No canvas, no skills or MCP, no constant prompting Reply if you'd like 200 free designs to give it try
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Eric Paley
Eric Paley@epaley·
My Next Chapter - Team Massachusetts I’m honored to share that Governor Healey has appointed me to be the Massachusetts Secretary of Economic Development. This is not a sentence I ever imagined I’d be writing. I’ve spent my career as an entrepreneur and venture capitalist. Although I studied Government as an undergraduate and interned long ago in Congress, I thought my career had permanently diverged into the private sector. And yet, I’ve long had a desire to serve and play a role in making a difference for my community. Accepting this appointment means stepping away from a position that, for 16 remarkable years, has felt nearly ideal. At Founder Collective, I’ve had the privilege of working alongside my closest friends and an exceptional team. Every day, I’m inspired by the brilliance and resilience of the founders we support—visionaries building technology to rethink our world. Founder Collective has become well known and respected for our mission-driven approach to venture capital, which puts founders ahead of funders and obsessively focuses on how to drive founder alignment as we partner with companies at the earliest stage. It was always my assumption that Founder Collective would be my professional home until retirement many years in the future. While I transition, I have absolute faith that Founder Collective’s vital mission will continue to thrive long beyond my time, capably driven by my phenomenal partners. My initial reaction to any career change was an emphatic 'no.' I’ve spent the last 26 years honing my craft and the past 16 years crafting a special institution. I simply have too many commitments and way too fortunate a position to walk away. But then I couldn’t sleep that night. My mind raced with the profound implications of an opportunity to make an impact on a scale I never envisioned possible. I’ve watched and admired how Secretary Hao has worked with Governor Healey to make Massachusetts a better place to do business, to live, and to innovate. I simply couldn’t say no to the call to step up to a much broader platform and help improve the community that I love. The inherent magic of startups lies in their ability to identify seemingly small, targeted products that, when skillfully designed, can scale to generate immense impact. I’m fascinated by the prospect of applying this entrepreneurial mindset to the state economy. While I have much to learn about the diverse economic pockets across our Commonwealth, my startup experience underscores the need to boldly experiment with game-changing interventions, then rigorously scale what unequivocally works. Applying this mindset to the role is wide ranging: from exploring how we can further scale our already incredible life sciences sector, to simultaneously engaging with leaders of our small towns and gateway cities to uncover the specific initiatives that will catalyze their local economic goals. It’s commonplace, even expected, to harbor cynicism toward government. I confess, I’ve shared some of that hesitation. Balancing diverse public interests is undeniably a challenging, often slow process. Yet, my initial exposure to the Healey-Driscoll Administration has been profoundly reassuring. I’ve been struck by the work ethic, dedication to integrity, and commitment to service of the people I’ve met thus far. I am inspired by the example set by our Governor and Lt. Governor, and I am eager to meet my future collaborators—those who are working hard to drive our state forward. I have now lived half my life in the Commonwealth of Massachusetts. I cannot envision a more exceptional place to raise a family, educate our children, foster intellectual exchange, and collaboratively define our forward-looking community. This dynamic state has enriched my life immeasurably, and now, it is my time to reciprocate. I am ready to play my part in designing our collective future. I’m under no illusion that this journey will be easy; we face formidable headwinds. Yet, this profound responsibility only intensifies my motivation to step up to the challenge. To my partners, our team, and the founders who work tirelessly to invent the future — I’m profoundly grateful. I have a lump in my throat knowing that I won’t be alongside all of you through all of your exciting chapters ahead. Thank you to the broader innovation ecosystem both in Massachusetts and nationally that has embraced and celebrated our unique approach to venture capital and provided an environment that makes it possible for innovators to take the risk of trying to birth dreams into reality. Secretary Hao, I’m so appreciative for your leadership and example - I know I have huge shoes to fill. I am deeply honored and grateful to Governor Healey and Lt. Governor Driscol for entrusting me with the critical mission of advancing the Commonwealth’s economic agenda. Most of all, thank you, Massachusetts, for being such an incredible home and platform to build a life. I will work my hardest to drive forward that promise to our fellow citizens.
Eric Paley tweet media
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ami
ami@amiyoshimura_·
who are the best pre-seed/seed investors who bet on young founders?
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Henry Shi
Henry Shi@henrythe9ths·
There's a shocking fact about AI that nobody tells you: You can catch up to the public AI research frontier in just 2 weeks. Yes, really. I've built a $150M annual revenue startup over the last 8 years and If I were to start a company today, I’d drop everything and go all-in on AI. But like many busy software builders, I felt lost—overwhelmed by the noisy, crowded and fast-moving modern AI landscape. And I wasn’t alone. So I spent my entire holiday diving deep into AI research—reading 30+ papers, watching hours of lectures, analyzing trends, and catching up to the research frontier. ✨ Here’s what I learned: - You don’t need months (or years) to catch up. - You don’t need a PhD or decades of ML experience. - You need fewer than 20 papers and 2 weeks to understand the major breakthroughs shaping AI today. It's because the technology is extremely nascent and most techniques that came before are no longer relevant: - ChatGPT is barely 2 years old and Transformers are only 7 years old. - Most game-changing discoveries happened within the last 4 years, driven by a few breakthrough ideas, scaling laws, and efficient matrix multiplication. The biggest secret? Many groundbreaking AI papers with thousands of citations are surprisingly simple and applied, like adding "let's think step by step" to the prompt, or simply asking the LLM over and over again to improve its answer (Self-Refine). I realized there are tons of founders and builders in the same boat—wanting to dive deeper into AI but unsure where to start. I've created an essential AI Guide that helped me catch up, in just 2 weeks, to the frontier of public AI research to figure out where the next opportunities and gaps were: - Curated list of only the most important papers - Simple explanations of key concepts - Clear pathway to understanding the frontier of modern AI It’s perfect for: - Founders expanding into AI - Builders wanting to innovate at the frontier of AI - Investors looking to separate the signal from the noise 👇 Want the full guide? - Like and Share this post - Comment "AI Guide" - I'll send you the complete guide (ps, I’m also teaming up with @VishalVasishth, co-founder of @obviousvc with @ev (focused on large-scale societal impact companies like Twitter, Medium, Beyond Meat), to host a small meetup to discuss what's working and needs to be solved in the AI stack in SF. Message me if you're interested)
Henry Shi tweet media
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Sean Glass 🇺🇸 🇿🇦🇪🇺🇬🇧 retweetledi
Alyssa Jaffee
Alyssa Jaffee@AlyssaJoyJaffee·
big news in BH reimbursement today, Biden administration just enacted a rule that mandates that mental health care in private insurance plans be covered at the same level as physical health benefits. hoping this has a positive impact for digital health & consumer access to care
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Josh Kopelman
Josh Kopelman@joshk·
1/ When we started @firstround in 2004, I didn't know what institutional investors did. Heck, I barely knew what venture capitalists did. First Round Capital's first fund was $7M. Then in July of 2007 I got this cold email from @nshalek who was then at the @Yale Investments office. After getting to know the Yale team, they decided to anchor our first institutional venture fund. And I quickly learned what institutional investors did ;-)
Josh Kopelman tweet media
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Josh Wolfe
Josh Wolfe@wolfejosh·
engineering + tech + bathymetry = heaven🏄‍♂️ (video of one of my first tries @KSWaveCo surf ranch–– backside + frontside on 6'6 firewire machado mashup)
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Sean Glass 🇺🇸 🇿🇦🇪🇺🇬🇧
@daveclark85 This is exactly the question I had when I saw this data posted and people pontificating about it. Nice to see a data driven response that suggests what I would have suspected - dpi 5 years in is not likely predictive of fund success - thanks for posting
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David Clark
David Clark@daveclark85·
So we quickly looked at our data to see if DPI in year 5 is a good predictor of final performance. We analysed 71 funds from vintage years 2005-2008. The correlation between year 5 DPI and current DPI was just 0.22. /1
David Clark@daveclark85

DPIs - it takes 10-12 years for a company to go from being founded to IPO. Don't expect much DPI in the first 5 years of an early-stage fund's life. Also, liquidity in VC comes in waves. 2021 was one of these waves. So, no surprise later vintages are lagging on DPI. /5

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Benjamin Ling
Benjamin Ling@bling0·
Dear VCs: If you were previously with First Republic, who does your fund banking now?
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Sean Glass 🇺🇸 🇿🇦🇪🇺🇬🇧
@MarioATX_MD @RebeccaCoelius Agree - it’s great if there are other ways to fund innovation and then to scale it - and I love it when founders retain large ownership, but healthcare services is hard to scale and significant capital investment is often needed. These changes could make innovation harder.
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Rebecca Mitchell, MD
Rebecca Mitchell, MD@RebeccaCoelius·
Can anybody explain who IS allowed to invest in or own at scale care delivery if this passes? ACA already said no more physician owned hospitals. Only risk adverse banks and existing corp medicine structures that aren’t PE backed? To be clear I take serious issue with companies missing clinical leadership, and PE quick flips. But this proposal smells very badly of unintended consequences.
Christina Farr@chrissyfarr

I spoke with three legal experts to dig into a California bill that could kill the friendly PC model in digital health. This is a very big deal. If you are in digital health, you should know about it. secondopinion.media/p/proposed-bil…

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