Shouvik Mani

@elhamazizi lab’s new paper in @genomeresearch introduces DIISCO, an innovative method for studying dynamic cell-cell interactions using scRNA-seqdata! The study led by @cam_park & @ShouvikMani offers insights into cancer treatment and cellular behavior: bit.ly/4gLr9lJ

1/🧵I’m excited to share recent work on differentiable causal discovery from @AchilleNazaret and me, supervised by @elhamazizi and @blei_lab. Open the thread for a brief tweetorial (Xtorial?) of our method. arXiv link: arxiv.org/abs/2311.10263

1) Super excited that COVET and ENVI by the gifted @DoronTheViking finally out in @NatureBiotech providing a powerful tool to analyze the rapidly accumulating spatial transcriptomics data. See x.com/dana_peer/stat… for the original BioRxiv tweetorial -->

1/6 Excited to share our new preprint, out today on #biorxiv, a large #singlecell effort studying response to adoptive cellular therapy for relapsed myeloid malignancy after #HSCT !!

I am still in shock! Deeply humbled & grateful to @TakedaPharma @NYASciences for this honor and for highlighting our work: tinyurl.com/3ua82h93 Huge thanks to the phenomenal trainees I am so privileged to work with, the supportive @ColumbiaBME @Cancer_dynamics @columbiacancer

1/4 Excited to share #DIISCO 🪩, a Bayesian method for inferring cell-cell interactions over time in longitudinal #singlecell data 😱 DIISCO takes in cell type proportions and receptor-ligand expression and outputs cell state dynamics and cell-cell interaction networks! 🕺💃

Almost 1200 innocent school girls across 15 cities in Iran have been the target of systematic gas attacks and poisoning *inside* schools. This biological terrorizing is suspected to be carried out by hardliners to stop girls from going to school @Malala's story is not far away 😔