Dirk Gerhardt aka SilverSit

26.1K posts

Dirk Gerhardt aka SilverSit banner
Dirk Gerhardt aka SilverSit

Dirk Gerhardt aka SilverSit

@SitSilver

Sound Money Advocat. Following markets since 1989. GOLD/SILVERbug.

Hamburg, Germany Katılım Şubat 2021
1.2K Takip Edilen2K Takipçiler
Sabitlenmiş Tweet
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
Alles, was ich in 2 1/2 Jahren Recherchen herausgefunden habe, hier verlinkt. Mit über 2.000 Quellen. facebook.com/10000044715681… Das war es für mich fürs Erste. PS: in der aufkommenden Erkenntniswelle ein Job, den ich auf keinen Fall haben möchte: des verlogenen Faktencheckers
Deutsch
13
41
99
10.4K
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@BioSRP Thank you. Can you please also check secondary and tertiary protein structures? Sometimes the devil is in the detail, like the Gal-3 homology in secondary structure with Pradhan insert TNGTKR.
English
0
0
0
3
Bioscience Resource Project
Bioscience Resource Project@BioSRP·
@SitSilver OK, I managed to check: D613 in SARS1 does not align with D614 in SC2. D614 in SC2 is in fact D600 in SC1 because SC1 has some small deletions at the very beginning of the spike protein that are not present in SC2. So they are not analogous changes (according to sequence anyway).
English
1
0
1
9
Bioscience Resource Project
Bioscience Resource Project@BioSRP·
This is a common misconception. D614G functions in all species tested, therefore it's NOT a human adaptation, it's an adaptation to transmission. It was the only consistent AA change for 9 months = PERFECT human adaptation; consider other species where AA changes start accumulating in the Wuhan strain straight away. And in biological terms, although D614G has structural ramifications these are not how its effects are mediated. Rather, D614G dampens the innate immune system, which is extra high in the nasal passages. So by doing this it enhances transmission (in and out). Hence the quantum leap in transmissibility it engendered. (And, importantly, DEFUSE does not explain this mutation.) D613G is not a thing except a typo?
Dirk Gerhardt aka SilverSit@SitSilver

@BioSRP Overadapted, but not ready. The Baric stabilisation mutation D613G/D614G was missing. But the makers were sure it would arise, like in 20% of their serial passages, as long as the base was big enough. So further obfuscation of origin, making it slow at the beginning.

English
2
4
18
3.7K
Dirk Gerhardt aka SilverSit retweetledi
PolyBio
PolyBio@polybioRF·
PolyBio’s Spring Symposium is tomorrow! Join us on Friday May 22 from 11 am-5 pm ET (3-9 pm UTC) for a full day of updates on PolyBio-supported research projects. Last chance to register! us02web.zoom.us/webinar/regist…
English
0
11
21
454
Richard H. Ebright
Richard H. Ebright@R_H_Ebright·
Jeffery Taubenberger--a Fauci acolyte, a Morens co-conspirator, and a promoter and practitioner of dangerous gain-of-function research--reportedly no longer holds position of Acting Director of the National Institute for Allergy and Infectious Diseases. statnews.com/2026/05/21/nih…
English
13
23
128
3.2K
Vipin M. Vashishtha
Vipin M. Vashishtha@vipintukur·
A new pathology study describes the lung findings in a 2-month-old infant who died from COVID-19–associated sudden unexpected infant death (SUID). ➡️ Researchers found extensive SARS-CoV-2 involvement in the lungs along with severe endothelial injury, microvascular apoptosis, and intense inflammatory cytokine activity involving IL-6, TNF-α, and IFN-γ. 1/
Vipin M. Vashishtha tweet media
English
7
32
76
2.9K
Zdenek Vrozina
Zdenek Vrozina@ZdenekVrozina·
This may be one of the more important long COVID papers in a while. A new study in Frontiers in Immunology suggests that COVID can trigger new-onset insulin resistance - and that this may drive abnormal NETosis in neutrophils months after infection🧵
English
12
167
478
14.9K
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@53v3n0fn1n3 Die Sternenflottenakademie ist auf der Erde, in San Francisco, und nicht auf der Enterprise. Hätte ich als Peer Reviewer sofort bemerkt... 😁🥳
Deutsch
1
1
1
54
🕯Seven of Nine, MD 🏴‍☠️
🕯Seven of Nine, MD 🏴‍☠️@53v3n0fn1n3·
"Förderung durch eine humorvolle Scheinstiftung, ein Verweis auf die Sternenflotten-Akademie an Bord der USS Enterprise" Was soll das heißen: "SCHEINSTIFTUNG"??? 😜
Dr. Bodo Schiffmann@BoschimoDr

Glaubt der Wissenschaft? - haben sie gesagt: Eine schwedische Forscherin hat eine erfundene Krankheit entwickelt, in offensichtlich gefälschten Papieren verbreitet — und zugesehen, wie KI Millionen von Menschen erzählt hat, sie sei real. Anfang 2024 hat Almira Osmanovic Thunström von der Universität Göteborg eine fiktive Augenkrankheit namens Bixonimania entwickelt — beschrieben als Augenlidverfärbung und Augenschmerzen, die durch blaues Licht von Bildschirmen verursacht werden. Sie hat zwei vollständig gefälschte wissenschaftliche Artikel auf einem öffentlichen Preprint-Server veröffentlicht. Die Artikel sind absichtlich mit offensichtlichen Hinweisen gefüllt worden: fiktive Universitäten in erfundenen Städten, Förderung durch eine humorvolle Scheinstiftung, ein Verweis auf die Sternenflotten-Akademie an Bord der USS Enterprise und eine ausdrückliche Aussage, dass der Inhalt erfunden sei. Selbst der Name war ein Hinweis — das Suffix „-manie" ist ein psychiatrischer Begriff und würde nie für eine Augenkrankheit verwendet werden. Nichts davon hat geholfen. ChatGPT, Google Gemini, Microsoft Copilot und Perplexity AI haben Bixonimania allesamt als legitime aufkommende medizinische Diagnose behandelt. Copilot hat sie als selten, aber real beschrieben. Gemini hat Nutzern empfohlen, medizinische Hilfe zu suchen. Die fiktive Krankheit hat dann die digitale Welt verlassen: Ein Team echter Forscher in Indien hat einen der gefälschten Preprints in einem Artikel in der Fachzeitschrift Cureus zitiert und Bixonimania als aufkommende, mit blauem Licht verbundene Erkrankung beschrieben. Der Artikel ist erst im März 2026 zurückgezogen worden, nachdem Nature die Zeitschrift kontaktiert hat. Die im April 2026 veröffentlichte Nature-Enthüllung hat deutlich gemacht, was das Experiment wirklich getestet hat: Nicht ob KI theoretisch getäuscht werden kann, sondern wie schnell gefälschte Informationen — wenn sie in Struktur und Ton wissenschaftlicher Literatur ähneln — von einem gefälschten Blogbeitrag in die formale Wissensbasis übergehen können, die medizinische Ratschläge und Forschung prägt. Die Antwort ist: sehr schnell. Quellen: Osmanovic Thunström, A. (2026). Scientists invented a fake disease. AI told people it was real. Nature. t.me/simonevoss

Deutsch
1
3
12
185
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@BioSRP Or you can say: Fine tuning stability for the 'foreign body' FCS, that has pros and cons itself. This fits to the other assessment or hypothesis that FCS was inserted in last, in a functional, chimeric backbone derived from serial passage/directed evolution/library style selected
English
0
0
0
4
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@BioSRP Overadapted but with brakes, to spread slowly at the beginning. Once the before known, quite common adaption arises, the virus got legs to run. All other stuff was inbreed before. I stand by my assessment. It was built so on purpose.
English
1
0
0
6
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@BioSRP Yes, SC1, but other SARSr viruses as well. This mutation arises in about 1/5 all the time with serial passage.
English
0
0
0
6
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@Naomi_D_Harvey This was quite often my impression. Many viruses have capabilities aquired, from beeing generalists to specialists. The old generalists capabilities tend to get lost or go into background. BUT: SARS-CoV-2 seems to have gained all binding capabilities of whole Coronavirae clade!
English
0
0
0
8
Naomi Harvey “PhD Witch” #WearAMask
Naomi Harvey “PhD Witch” #WearAMask@Naomi_D_Harvey·
Long Covid is not lung damage Long Covid is not diabetes Long Covid is not pericarditis Long Covid is not POTS Long Covid is not MCAS Long Covid is not tinnitus Long Covid is not ME Long Covid can be any, or all, of them.
English
10
10
116
1.9K
Naomi Harvey “PhD Witch” #WearAMask
Naomi Harvey “PhD Witch” #WearAMask@Naomi_D_Harvey·
@SitSilver There was a recent study showing the damage the N protein can cause for example. So at the moment I’d just clarify it as ‘the virus’ itself. The spike can do a lot of it on its own though as we see from post vaccination damage.
English
2
0
3
38
Dirk Gerhardt aka SilverSit retweetledi
The Only Marc Favell
The Only Marc Favell@marcfavell·
🚨🚨 The world needs to talk about what the NIH RECOVER data is Covid saying because people are missing the point. Long Covid isn't just "Feeling tired" after getting sick. It is a multi-system, full-body wrecking ball, That shreds the vascular system and even the brain, Every single time you get reinfected If you know it or not, the risk compounds. The virus hides in your gut, your heart and your brain. It creates viral reservoirs that just sit there and pump out chronic inflammation. It wrecks your T-cells, shreds your blood vessels, and forms microclots/DVT's. And the brain fog? It is literally microglial activation. Your brain cells are inflamed and accidentally pruning away healthy synapses. It causes POTS because your vagus nerve gets damaged. It kills your mitochondria so your body literally cannot make energy. It is actual organ damage.But the worst part is what we are doing to kids. Since 2020, children’s baseline health has completely shifted. Parents and doctors are looking at kids who suddenly have mood swings, memory drops or can't keep up in school, and they are blaming it on "screen time" or "pandemic anxiety". That is dangerous diagnostic gaslighting. It is the virus. It is neurological damage and pediatric multi system inflammation.We have to stop tracking just "acute cases" and start tracking total infection counts. Every infection matters. P.S. It is now 2026 and not a single doctor, nurse practitioner, internist or specialist has ever asked me how many times I’ve had Covid. That question is a 💯 relevant foundational question. 🤯 Failing to track cumulative infections at this stage is a terrifying combination of medical malpractice and pure ignorance. It is impossible to take any of them seriously when they treat patients completely maskless without an N95. I have been following the research, they clearly haven't and frankly, I could school them on the data they are actively ignoring. 🚨 Stop ignoring the data.😡 #SARS2 #Covid #LongCovid #Gaslighting #ABC #AnythingButCovid ajmc.com/view/long-covi…
English
6
95
224
3.6K
Dirk Gerhardt aka SilverSit retweetledi
Dr Elisa Perego
Dr Elisa Perego@elisaperego78·
Six years ago today the term #LongCovid was first used as a Twitter hashtag. A single tweet by a patient linked together a growing grassroots movement of people, who weren't recovering from covid. Across the world, we're still fighting for research and treatment of our disease
Dr Elisa Perego tweet media
English
7
128
347
6.5K
Dara in Chains
Dara in Chains@DarainChains·
All of the known receptors the whole virus can enter through and their mechanisms. If I missed any please feel free to add in the comments.
Dara in Chains@DarainChains

Here is a big post about every cell SC2 infects in the body that we know of so far. ## Comprehensive Overview of SARS-CoV-2 Receptor Locations Why can't we just worry about the spike protein? SC2 binds to various receptors across multiple body regions, allowing for entry into diverse cell types. Here’s an expanded list of the receptors, their associated cell types, and specific anatomical locations throughout the body, including the brain and major organs. 1. ACE2 (Angiotensin-Converting Enzyme 2) - Cell Types: Epithelial cells, endothelial cells - Locations: - Lungs: Alveolar type II cells - Heart: Cardiomyocytes - Kidneys: Proximal tubular cells - Intestine: Enterocytes in the small intestine - Blood Vessels: Endothelial cells lined in arteries and veins - Testes: Leydig and Sertoli cells - Nasal Epithelium: Ciliated epithelial cells - Mouth and Throat: Oral epithelial cells 2. TMPRSS2 (Transmembrane Protease, Serine 2) - Cell Types: Epithelial cells - Locations: - Lungs: Respiratory epithelial cells - Prostate: Prostate glandular cells - Intestine: Enterocytes of the small intestine - Pancreas: Ductal cells 3. Dipeptidyl Peptidase 4 (DPP4) - Cell Types: Immune and epithelial cells - Locations: - Lungs: Epithelial cells - Pancreas: Islet cells (β-cells) - Kidneys: Renal tubular epithelial cells - Heart: Cardiac fibroblasts - Brain: Neuronal cells 4. Neuropilin-1 - Cell Types: Endothelial and neuronal cells - Locations: - Lungs: Vascular endothelial cells - Brain: Neurons and glial cells (including astrocytes and oligodendrocytes) - Heart: Cardiomyocytes - Intestine: Intestinal epithelial cells 5. Heparan Sulfate - Cell Types: Present on diverse cell types - Locations: - Lungs: Epithelial and endothelial cells - Blood Vessels: Endothelial cells throughout the circulatory system - Brain: Neurons and glial cells - Muscle: Skeletal muscle cells - Skin: Dermal fibroblasts 6. Furin - Cell Types: Various human tissue cells - Locations: - Lungs: Epithelial cells - Brain: Neuronal cells and glial cells - Heart: Cardiomyocytes - Pancreas: Exocrine pancreatic cells - Intestine: Enterocytes 7. CD147 (Basigin) - Cell Types: Various cell types - Locations: - Lungs: Epithelial cells - Brain: Neuronal cells - Heart: Myocardial cells - Immune System: T cells and macrophages throughout the body 8. KREMEN-1 - Cell Types: Developing tissues - Locations: - Embryonic tissues: The exact roles in adult tissues are still under investigation. These receptors and their distribution across various organs, including the lungs, heart, kidneys, intestines, brain, and skin, contribute to the wide-ranging effects of SC2 infection and its potential complications in multiple systems throughout the body. So while vaccine injury is happening, it's only to do with 1 type which is the Spike2. Next let's look at megakaryocytes and why that is important in LC.

English
1
9
25
936
Dirk Gerhardt aka SilverSit
Dirk Gerhardt aka SilverSit@SitSilver·
@BioSRP Similar can be said about the pan mammal ACE2 binding, that is only bad in bats. Though optimal for humans? x.com/SitSilver/stat… pmc.ncbi.nlm.nih.gov/articles/PMC85…
Dirk Gerhardt aka SilverSit@SitSilver

@breakfast_dogs @RSGopalan3 @MonaRahalkar "The common vampire bat is the only species that showed susceptibility among the 6 bat species analyzed, both in the spike–ACE2 binding assay and the live-virus infectivity assay." pmc.ncbi.nlm.nih.gov/articles/PMC12…

English
0
0
0
53

Keşfet

@BioSRP @R_H_Ebright @53v3n0fn1n3 @vipintukur @DocFlo4 @DrGrahamLJ @ZdenekVrozina @Naomi_D_Harvey