SpineCloud

@rand_longevity You’d be insane to not want to try this

hmmm would you buy this?

@kimmonismus So sick

Update on OpenAIs device: reportedly itll be a screenless, camera-equipped AI companion designed to feel alive. Bloomberg’s Mark Gurman says OpenAI is building a battery-powered smart speaker that can be carried around the home. It will control appliances, play media, answer messages and understand its surroundings through cameras and sensors. Its personality is supposed to become more humanlike and proactive over time. It will learn from habits, context and personal information, including emails, to anticipate what its owner needs. Mechanical elements will move on their own to make the device feel alive. OpenAI internally calls it "a computer built for AI." The device will use GPT-Live, which can listen and speak simultaneously. Jony Ive’s LoveFrom is designing it after OpenAI’s $6.5 billion acquisition of io Products. OpenAI plans to unveil it this year and ship in 2027, unless Apple’s trade-secret lawsuit delays it. 1) It seems like they're incorporating the experience gained from OpenClaw, creating a device that automates daily routines and can be programmable. 2) GPT Live appears to be a first glimpse of this.

@JimViviano @CoachDanGo This is bad advice. I agree with you, screen time doesn’t affect t me at all. I’ve tested it. I’ve tested no blue lights, no screens, no difference in my sleep. The advice should be more…there’s a chance you might be sensitive to blue light.

@notch Decels are the definition of pathetic

Reject AI.

@AlexanderKalian Put differently, it’s something like 40 years typically from strong medical idea, to actual consumer use/availability. Unacceptable

@AlexanderKalian Right now we have a system that if 1 person dies during a trial, they voluntarily signed up for, knowing risks, the entire field of study gets shut down. While I get your point, I think we’re so far in an extreme of fear regarding human trials, it’s made progress so so slow

You really can't make this up. Yesterday, I accused tech circles of overconfidence about AI in biology - e.g. blurting "AI will cure cancer in 5 years!" - without understanding clinical trials or basic pharmacology. The result? A mass of comments from tech bros downplaying the need for clinical trials! They basically doubled down on their overconfidence about a field they have not seriously studied or researched. Well, bad news, guys - biology is not code. It is highly complex, high-noise, high-failure, R&D-heavy for wet labs, and full of painful unknowns and edge cases. Your Python skills and vibe coding don't give you insight into the nuances of drug development. Thank goodness these people are not in charge of any serious biomedical research programs. Many of them even advocate going straight from AI discovery to human trial, without the years of slow, expensive preclinical studies on mice. Well, ~100 million mice die each year, for these studies. Most are euthanised for analysis of their tissues, but a substantial subset directly die as a result of candidate drugs being toxic. Millions of people would literally perish every year, instead, if these overconfident tech X guys were to be in charge.

@mark_k Cave people decels are probably the biggest smelliest group of losers we’ve ever seen.

Reject Decels, Doomers, and AI Haters.

@misraetel @dwarkesh_sp @_sholtodouglas Look at all those guys on their way towards biological immortality. Brings a tear to the eye 😢

Huge fun training the @dwarkesh_sp podcast folks as well as a lone, wandering @_sholtodouglas. These guys CRUSHED! And only one person died! Success!

@kimmonismus Love it . Just hope we break thru the whole…from amazing idea…40 years later it becomes available for use

One dose of a frog-gut bacterium completely eliminated colorectal tumors in every treated mouse. Not merely shrank them. Complete response. The bacterium, Ewingella americana, multiplied roughly 3,000-fold inside the tumors within 24 hours. It attacked cancer cells directly while recruiting T cells, B cells, and neutrophils. In the experiment, it outperformed four doses of anti-PD-L1 immunotherapy and liposomal doxorubicin. Then researchers rechallenged the cured mice with the tumor: 0/10 developed tumors. 10/10 untreated mice did. The bacterium disappeared from the bloodstream within 24 hours and wasn’t detected in healthy organs. It’s one small mouse study, not a human cancer cure. But the concept is remarkable: a living drug that finds the tumor, multiplies inside it, destroys it, and potentially teaches the immune system to remember. In the foreseeable future, we will cure all cancers.

@Jason @Cobratate In Los Angeles, how much jail time you think he got for this? Easy answer: likely 0

.@Cobratate is out of control

@wholemars This doesn’t happen in China because this person would get 20 years in jail, probably worse. In Los Angeles, this person gets a citation and no jail time. Hence why LA is a shithole

pure vision solves this issue

@kimmonismus The hard left anti tech movement is serious threat to everyone. They want everyone to just accept their biological death sentence.

this is so stupid. we got much educational work to do friends.

@Polymarket Perhaps the largest collection of losers on the planet, found right there

JUST IN: Hundreds protest outside OpenAI, Anthropic, & Google DeepMind offices in SF, demanding a halt to AI development.

@beffjezos Ah yes the new far left movement. Let’s make sure we don’t improve society! Stop it now!

POV: you attend the undiagnosed anxiety disorder convention

@mark_k 1 more step towards biological immortality

Saturday is gym day. Perfectly empty right now, calm and great for focusing. Wish you a happy Saturday! 🌞

@bryan_johnson Solve aging asap

Eager to hear your life advice. What should I be doing?

@iruletheworldmo Wil the trump admin cock block us again? Hope not

gpt 6 coming soon? is this what an intelligence explosion feels lime 🥹

@CarloItalo1234 @daveasprey I agree most claims of over training are from people who look like sticks out of prisoner of war camps. I just do length of workouts that pretty muscular people do, which isn’t really that long. But certainly longer than 20 mins

@gdb And it’s massively superior to fable regarding health because get what, fable won’t allow any biology or health questions! Insanity

GPT-5.6 for health intelligence, the team has been focusing hard on improvements here:

@juliankissa @tomfgoodwin It’s 2026. Like…humans without ac in hot conditions is a total joke. We basically have agi right now. Like what lol.

@tomfgoodwin BS. Tom, you know it’s hot. It’s just your conference, and possibly hotel, has AC. Try staying in a stuffy Victorian house with relatively poor ventilation for a week

It’s really not that hot in the uk. It’s just that everyone goes up to everyone and says “wow it’s hot” and then we all convince each other it is. At a conference in London this week it’s all people could talk about. Wear natural fibers, walk a bit more slowly, enjoy feeling warm. It’s dry heat , it’s wonderful . It’s humidity that sucks