Stampton

@BGH1968 @bennetthaselton @NewCaliNeighbor @memeticsisyphus Only the right dog whistl’s

@bennetthaselton @NewCaliNeighbor @memeticsisyphus What does he infer, or perhaps for the lower orders, “dog whistle”?

It happened exclusively because of online censorship. You simply couldn’t be an open conservative online (or in many left wing companies/ universities) for like a decade. The end result was things like mainstream democrats advocating for government taking children away from parents if they didn’t transition them or abolish prisons. I think about this quote a lot: “So the conservative who resists change is as valuable as the radical who proposes it—perhaps as much more valuable as roots are more vital than grafts. It is good that new ideas should be heard, for the sake of the few that can be used; but it is also good that new ideas should be compelled to go through the mill of objection, opposition, and contumely; this is the trial heat which innovations must survive before being allowed to enter the human race. It is good that the old should resist the young, and that the young should prod the old; out of this tension, as out of the strife of the sexes and the classes, comes a creative tensile strength, a stimulated development, a secret and basic unity and movement of the whole.”

@jaradkoby @AviBittMD You would expect that placebo patients to have negative changes in cognitive scores because their Alzheimer’s is continuing to progress.

@AviBittMD Obviously I've never done research for Alzheimer's, but my guess is that the brain naturally degrades over time anyway. Wouldn't placebo performing at a negative make sense in that case?

This is basically on the level of Hasan Piker endorsing Ivermectin for COVID during the early slop trial publication days. The claimed "working" treatment for Alzheimer's has an non-replicated and a biologically implausible effect size result that should call its trial into question. Specifically, the effect size in the ATHENEA trial (NeuroEPO plus) appears implausibly large when benchmarked against decades of Alzheimer's disease clinical trial data, particularly on the primary outcome: change in ADAS-Cog11 score at 48 weeks. Median ADAS-Cog11 change: -3.0 to -4.0 points (improvement) in the two active doses. Placebo: +4.0 points (worsening). Net treatment differences: 7.0 to 8.0 points This equates to treatment groups showing cognitive improvement while placebo worsened substantially, yielding an absolute benefit of ~7-8 points over 48 weeks. Not only is this far greater than the largest realistic effects in approved/symptomatic therapies (Donepezil, rivastigmine, galantamine: Peak benefits of 2–4 points vs. placebo, often at 6–12 months, then fading), it further shows an even more implausible reversal of disease. AD is relentlessly progressive; no neuroprotective agent (including EPO variants in other trials) has reversed cognitive scores. At best, one can hope for slowing or halting the disease. Improvement reported in this trial suggests reversal of deficits, and all in the face of discordant data. Hippocampal volumetry was neutral in the RCT: identical atrophy rates across active and placebo arms. Percentage change: ≈ −3.40% (0.5 mg dose), −3.26% (1.0 mg), −3.32% (placebo); p ≈ 0.98 (neutral across arms). This indicates no slowing of hippocampal atrophy despite the large cognitive benefits claimed. Cognitive reversal without any slowing of structural neurodegeneration is biologically discordant. AD cognition tracks closely with hippocampal loss. The authors speculated about “functional/synaptic” benefits to try and explain this, but this remains speculative and would require extraordinary evidence (synaptic density imaging, which wasn’t done). In other words: The brain continues to die, but the paper is reporting clinical reversal of disease. That is a huge red flag of discordance and should call the trial results into serious question. The manufacturer of this drug (Center of Molecular Immunology) designed, funded, analyzed, and authored both this trial and the follow-up study with even more far-reaching, less plausible results (this alone does not invalidate the results, but it should be noted in light of the implausible results). To date, this has never been replicated, and every published human clinical trial result (efficacy, safety, follow-up) on NeuroEPO/NeuralCIM in Alzheimer's is from Cuban research teams, sites, and sponsors (primarily CIM). If this is truly the Ivermectin-that-actually-works-miracle-story for Alzheimer's...great, I look forward to seeing the replication outside of Cuba. Until then, you should be skeptical, and you should definitely stop taking Hasan Piker seriously on medical treatments.

@ChrisLandauUSA @FischerKing64 Because crime’s are caused by inequality try arresting capitolism not people who are forced into crime’s

Last fall, as my 86-year-old father-in-law lay dying of cancer at his home in Lakeland, Florida, the pool guy told my wife—who was tending to her dad—that he was owed $2,000 for past services. He claimed that he’d left my father-in-law’s check “out in the rain” and it had been ruined. Although distraught over her father’s situation, my wife is a sensible person and asked to see the “ruined” check before writing a new one. Weeks pass, and the pool guy starts to get pretty aggressive about demanding payment, before he finally produces the “ruined” check on which he also claims to have spilled ink (!)—and shows her many other similarly “ruined” checks. My wife logs into her father’s bank account and sees that the check—in perfect condition—had been cashed by the pool guy months earlier. So he’s obviously trying to take advantage of her vulnerable situation to scam her. We were outraged and concerned that he’d pull this stunt on others, so we immediately contacted the Polk County Sheriff’s Department. We were assigned a Detective to whom we presented the evidence: emails demanding payment, the copy of the bogus “ruined” check, and the bank’s copy of the intact check that was cashed. Alas, they’ve now ghosted us since we last reached out 3 months ago asking for an update. And that brings me to my point: I don’t know what’s happened in our country, but our law enforcement agencies and prosecutors seem more interested in doing their paperwork than in actually enforcing the law. I hope we can change this before people stop bothering even to bring wrongdoing to the authorities’ attention, as has happened in many other countries. The rule of law requires enforcement of the law!

@DaRyo1989 @Mericamemed I use to watch it as a kid and this is how he talked

@Mericamemed It's funny because that's not how Barney talks. He is talking super ghetto and is referencing things which makes this hilarious.

If this were the way the real Barney talked, nobody would have hated him.

@DrewPavlou Nobody is saying it’s good it right belief’s are more important than electricity

So grim that Kneecap were able to host a concert in Havana while the Cuban dictatorship rations power and denies electricity to its own people

@EMartin45281993 @SteveLovesAmmo But the joke also makes light of the falsehood by irreverence.

@Stamptonoid @SteveLovesAmmo I know, but the joke relies on a common misstatement of fact.

This is such a fantastic twist.

@JTAlexander_ Look he did all he could of done it’s not his fault the media didn’t publicize his finding’s

People with short memories and young ages cannot remember, but the Mueller Cult was an absolutely real and extremely bizarre thing. Leftists were acting like he was their Lord & Savior because they honestly believed he was going to put Trump in a SuperMax prison.

@MarieIsabellaB @visegrad24 @ImMeme0 This is from the inbargo read a book 🙄

@visegrad24 🤨

Angry Cuban man goes to the hotel where the Code Pink communists are staying in Cuba. They get to enjoy electricity thanks to a generator but 99.9% of Cubans are without electricity tonight after the nationwide blackout 🇨🇺

@NatCon2022 Yeah but when 400 year’s they’re has to be at least some

Today is the 17th anniversary of the massacre of four Oakland cops by career criminal Lovelle Mixon. Authorities had just linked Mixon's DNA to three rapes, including a 12 year-old victim. Over 50 Black Supremacists held a public parade honoring Mixon.

@TatorTrucking @Michaeldudufudu Where can I get a hare cut like that

@Michaeldudufudu I like trucking because I make money.

Black people discovering they can make money by working

@Mekarrrr @JRobFreedom @feelsdesperate To be a journeyman electrician you can graduate high school and work 3 years as an apprentice. To become a master electrician requires years of experience as a journeyman or being an electrical engineer plus passing an exam. Master electricians make more than teachers.

@JRobFreedom @feelsdesperate This struck me as wrong so I looked it up and yep, you’re right. It’s not a huge difference but teachers do make more on average than electricians.

I would rather drop $200 billion of gold bricks into the ocean than give it to teachers.

@LifeHaxx101 Why did we put the spoon on the sledge hammer

Easy DIY ideas to upgrade your life

@oldwomaninwoods @AmiriKing Should *go to prison* for a period of 10 years

@AmiriKing Not sure why you threw the race thing in there but anyone rents under a government program and destroys the property should be banned from all tax payer funded programs for a period of 10 years.

A black family got busted violating their section 8 by renting out a room in their house. They were kicked from the program so they destroyed the property they were staying in. Unreal.

@GodofBlunder247 @WoosterJeeves2 @BtcSatoshiBtc @CodifyBaseball If the border of the zone is not a strike, you would need a border of that area that is considered a strike. That would be the new border

The strike zone literally does have a border though. I don't think you're getting what I'm saying There's literally a zone and then literally a border. I understand that a ball touching the border is considered a strike. So the border is a strike. Not arguing any of that. Why would I. I'm making a more thoughtful argument that's going over your head

a week's worth of successful defensive ABS challenges

@DudespostingWs Being tall is positive. You get your pick of women. People see you as a natural leader. They are more likely to vote for you in politics or promote you in the corporate world. Being fat is negative. You are rejected by most romantically. Your health outcomes are worse.

Imagine if we treated fat people the same way we treat tall people

@PolymarketSport White Howard

Cream Abdul-Jabbar Milk Chamberlin LeBron Frames Steph Blurry Larry Nerd

@PolymarketSport Dikembe Pale-tone-bro

@JLimebrook @iowahawkblog @PolymarketSport Awful

@iowahawkblog @PolymarketSport Lactic Johnson.

@SportsAICant @PolymarketSport These are horrible. Congrats

@PolymarketSport Mayoses Malone