Rick C312

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I tried NK + Vit K2 at the maximum dose in studies (12000 FU/day) for several months, with blood tests every 2 months, and I observed no effect on cholesterol reduction. Zero. I also saw no effect with phytosterols or berberine. I've only seen LDL-lowering effects with BPF (bergamot), which contains two statin-like compounds.

Why would nattokinase decrease cholesterol and cause plaque regression? Mechanistically. That part doesn’t make any sense to me. I’d love to see someone repeat some of the nattokinase studies. Now. I’m a fan. It’s a daily driver. But I also want to be cautious about potentially overselling it.

@Jebus Movies have been so bad for 10 years that anything that's just mediocre now passes for a great movie

It was good Worth going to see for sure But I think people are going a little overboard

👀

@PeterDiamandis This is simply not true. AI-powered programming tools are not approved for internal use, nor are they expected to be approved in the near future, everything has to be done manually. What IBM is hiring are cheap consultants in India and Morocco, who just happen to be young.

IBM is hiring MORE entry-level employees because young people are better with AI than older generations.

@apoorveth @SkyEcosystem What if you just stop using those protocols instead of whining?

Wow @SkyEcosystem 👏👏 so tired of these non-cyberpunk bs in this space

Senolytics are generally a risky treatment because senescent cells also perform important functions in the body, such as wound healing. Therefore, they should not be taken lightly, and especially not continuously. Studies like this one reinforce the idea that, if used, it should be in intermittent and very short protocols.

A combination of senolytics causes neuropathology in mice 👀 Dasatinib and quercetin trigger oligodendrocyte dysfunction and white matter injury in the CNS. Senolytics under more scrutiny? nature.com/articles/s4158…

If Trump really wants to finish off Iranian uranium quickly, he only needs to tokenize and list it on Hyperliquid and it will immediately go to zero

@mert Rated as useful 🫡

this is the greatest community note, in the history of community notes, maybe ever

@AlgodTrading Hyperliquid did. Starting to think this is a more broad crypto thing

S&P500 trading as if Binance listed it

Crypto is the Jim Cramer of markets. Anything you list there gets instantly nuked

@frankdegods Here x.com/TrueRick312/st…

i haven’t seen a bull post in weeks

Confirmation bias. People with high IQs and high agency who regularly associate with their peers tend to overestimate the abilities of the general population. No matter how much the cost -understood in broad terms of difficulty and time, not strictly economic- of creating an app tends to zero thanks to AI, allowing even people with low IQs and no formal education to (in theory) create their own app, this alone can never compensate for the lack of agency -motivation or drive- or the mere tendency to procrastinate that most people exhibit. If you need more proof of this, just look at the history of content creation or even social media contributions and interactions since the early days of the internet. What percentage of people write social media posts? How many comment? How many like or repost? 99% will always consume the products created by the other 1%. It's human nature. AI isn't going to change that, no matter how much it improves.

I just had to set up a VPN in Guatemala to be able to withdraw my funds from Hyperliquid. I've been warning for a long time that it's another centralized exchange, but with extra steps, and if they block your funds, you have no one to turn to. When shit hits the fan, don't say you weren't warned.

@HyperliquidX has started randomly blocking user accounts with the excuse of being in a sanctioned jurisdiction, which of course I'm not. Once blocked, you can't withdraw your funds, and since this is "decentralized," you have nowhere to file a claim. I recommend everyone withdraw their funds from this scam ASAP before it's too late and you lose access to your funds, as just happened to me.

@stacy_muur And we wonder why crypto is cooked. The entire system is a scam, starting with the blockchain protocol.

On March 12, a user swapped $50.4M on Aave and got back $36K worth of tokens. A lot has already been written about it. I'm not here to talk about that. When I was digging into what actually happened, I read ~$34M went to Titan, the block builder who controlled transaction ordering for that block. After seeing the name Titan, I thought I'd write about block builder concentration in Ethereum. Ethereum has ~1M validators. It's marketed as the most decentralized chain in the world. But most blocks are controlled by the top 3 builders: Titan, Buildernet, Quasar. These companies decide what goes into 90%+ of Ethereum blocks. One million validators. very few gatekeepers. How did we get here? After the Merge, Ethereum adopted PBS (Proposer-Builder Separation). Validators propose. Builders build. Theory: healthy open market. Practice: winner-takes-all latency game. Whoever is fastest, has the best private order flow deals, and extracts the most value wins the MEV-Boost auction. Winning compounds. More blocks → more data → better strategies → more order flow → more blocks. Market has been consolidating ever since. Here's what nobody wants to say: To win the PBS auction, you build the most extractive block possible. Sandwiching users. Front-running trades. Ordering transactions to maximize value capture. These aren't side effects. They're the winning strategy. We built a system that rewards whoever harms users most efficiently. How valuable is a vast validator network when the content of every block is decided by a handful of entities optimizing purely for extraction?

@MsMelChen Please 😌

Iconic moments in Trump diplomacy You think he won’t really go there but then he does

There are too many things to price in right now. Extremely difficult market.

@ChrisJBakke Let's not forget the door to the void on the 70th floor for when you want to end it all quickly.

You will live in the AI slop apartment. Your clothes washer will be under your kitchen sink. You have no dryer. There's wood paneling on the walls for some reason. You will smile at the candle that is burning 4 inches away from your 24 foot tall curtains. You pay $20,000/mo and can't access the stairs up to your shitty loft bedroom. There is no bathroom. You will be happy.