TuguesLab

Excited to share our new study out in @NatureComms ! 🎉 We show that NK cell localization in the lung determines their ability to eliminate tumor cells. 🫁 nature.com/articles/s4146…

Myers, Reilly, & Brossay @BrownUniversity discuss work by @csparano93, @SolisSayago et al. @TuguesLab (hubs.la/Q03155TM0) which shows that tissue-resident NK cells produce TGF-β1 themselves to establish and maintain residency in glandular tissues. hubs.la/Q03157gF0

Autocrine TGF-β1 drives tissue-specific differentiation and function of resident NK cells, say Colin Sparano (@csparano93), Darío Solís-Sayago (@SolisSayago), Sonia Tugues @TuguesLab and colleagues @UZH_en: hubs.la/Q0302VDw0 #InnateImmunity #LymphocyteBiology

Excited to share our new paper in @JExpMed 🎉 We show that NK cells use autocrine TGF-β1 signalling to establish tissue residency, form a highly cytotoxic subset, and protect the tissue against viral persistence. rupress.org/jem/article/22…

Visit the Novel Concepts in #Innate_immunity #Conferences website to submit an abstract and see a list of confirmed speakers, e.g. @BrunoLemaitre3, @laoneill111, @AudeBer, @ClareBryant13, @v_hornung, @LabLeibundgut, @LennonLab, @lloyd_lab, @rosa_paolicelli, @SarrisLab, @TuguesLab

I had a good time in Lyon at my first "NK&ILC Meeting"; great science, talks and people! Thanks to the German Society of Immunology (@dgfi_org) for having gathered all these amazing scientists from around the world. @TuguesLab

New position is open! Cerwenka and Tugues lab will work together on innate lymphocyte responses in metastatic melanoma and immunotherapy

Looking forward to visit Zurich next week🫶 Please come to give us some comments for our T cell exhaustion project which I am super excited about🫡

@DergunStanislav Good luck with the new beginning Stan! You will be missed here!

Let the journey begin!

Thrilled to share our latest collaboration with @Becherlab: "IL-23 stabilizes effector Treg program in tumors" by @WertheimerT and @PascaleZwicky et al. out now in @NatImmunol. Check out the great tweetorial of the @Becherlab !

B cell depleting therapies effectively treat #MultipleSclerosis, yet our understanding of why remains limited. How does loss of B cells impact the immune system in MS? See our multicohort study employing high-dimensional single-cell immunophenotyping: cell.com/cell-reports-m…

Now out in Science Immunology! Our work on how metabolic stress of hepatocytes triggers inflammation in NASH. First clues for a non-invasive biomarker for the disease in humans science.org/doi/10.1126/sc…

Excited to share our work on Tregs in the TME at this fantastic conference #CICON23! @BecherLab @TuguesLab @PascaleZwicky @AACR @ENCI_network @CancerResearch

Enjoyed a wonderful meeting in Würzburg! Thank you for bringing together so many great people from the NK and ILC community @GeorgGasteiger

@DrJHSchroeder @globalimmuno Thanks! Indeed, quite interesting to see this costimulatory marker on ILC1s (we see it specifically on these early, "helper-like" ILC1s but also on immature NK cells). We don't know it's relevance but some old studies suggest on NKs it's functional and can induce proliferation.

@globalimmuno @TuguesLab Thank you for your talk! I really enjoyed that. Your scRNA-seq data indicate that hepatic ILC1 can express Cd28. Do you know the relevance of this? twitter.com/hashtag/global…

Please ask questions for today's Global Immunotalk by Dr. Sonia Tugues HERE by replying to this tweet. Don't forget to mention #globalimmuno. Sonia will use the account @TuguesLab to answer questions.

Looking forward to our next #globalimmuno talk this Wednesday, May 3rd at 9am PST, noon EST, 4pm GMT by Dr. Sonia Tugues. Title: “Ontogeny and anti-metastatic function of group 1 innate lymphocytes” LINK: ucsd.zoom.us/j/91053505061

@GeorgGasteiger @dgfi_org @RomagnaniLab @DiefenbachLab @CerwenkaLab @Wue_SI @timotheus_halim @JBoettcherLab @GMWiedemann Thank you for organising, we are very much looking forward!

...organized by by @dgfi_org and spp-innatelymphoidcells.de, @RomagnaniLab, @DiefenbachLab, @CerwenkaLab @Wue_SI and many more speakers @timotheus_halim, @JBoettcherLab, @GMWiedemann, @TuguesLab, more coming soon... - limited spots in a great location & winery!

Interested in Tissue Homeostasis and Immunity? NK cells and ILCs? join this fantastic nk-symposium.org with lots of exciting science from @SunLab_Official, @EricVivier1, @maini_lab, @LMackayLab, @bjorkstrom_lab, @Molofsky_lab, @Hepworth_Lab...

@obrunomarcel @fmrp_usp Congratulations Bruno!

Last week I successfully defended my PhD thesis at @fmrp_usp. Couldn’t be happier after so much learning and growing over the last few years! Thanks everyone involved in this journey!