Kwamina Nyame

114 posts

Kwamina Nyame banner
Kwamina Nyame

Kwamina Nyame

@Tyfic_Gh

PhD Candidate| Biochemistry Stanford University |Life is short. Smile while you have teeth #Rhythms of Grace #LivingaLegacy IG @tyfic_gh Facebook: Kwamina Nyame

Tarkwa Ghana Katılım Temmuz 2016
335 Takip Edilen345 Takipçiler
Sabitlenmiş Tweet
Kwamina Nyame
Kwamina Nyame@Tyfic_Gh·
Big News: Thrilled to share that my latest PhD work is now published in @Nature. We identify PLA2G15 as the lysosomal BMP hydrolase and show that blocking it improves outcomes in a severe neurodegenerative disease model. Read the article here tinyurl.com/3b9zt5fw (1/7)
English
11
39
175
18.3K
Kwamina Nyame retweetledi
Sarafan ChEM-H
Sarafan ChEM-H@Stanford_ChEMH·
#YearInReview Work led by @Tyfic_Gh & Jian Xiong in @abu_remaileh lab identified the enzyme PLA2G15 as a lysosomal degrader of BMP, a lipid that is misregulated in neurogenerative disease, providing a potential new access point for treatment: brnw.ch/21wYASI
English
0
1
2
251
Kwamina Nyame retweetledi
Stanford University
Stanford University@Stanford·
For neurodegenerative diseases like Alzheimer’s and Parkinson’s, treatment options are scant. New research identifies a promising access point to therapeutics. news.stanford.edu/stories/2025/0…
English
17
39
119
20K
Kwamina Nyame retweetledi
Judith Simcox PhD
Judith Simcox PhD@JudithSimcox·
One of my favorite parts of this story is the behind the scenes where we were able to work with @abu_remaileh and @Tyfic_Gh on a second Pla2g15 paper. Science is great because it’s not isolated discoveries but validation by multiple groups. nature.com/articles/s4158…
English
1
3
19
1.2K
Kwamina Nyame retweetledi
Sarafan ChEM-H
Sarafan ChEM-H@Stanford_ChEMH·
Work led by @Tyfic_Gh & Jian Xiong in the lab of Institute Scholar @abu_remaileh identified the enzyme PLA2G15 as a lysosomal degrader of BMP, a lipid that is misregulated in neurogenerative disease, providing a potential new access point for treatment: news.stanford.edu/stories/2025/0…
English
0
4
13
2.4K
Kwamina Nyame
Kwamina Nyame@Tyfic_Gh·
This project began with a serendipitous observation and grew through incredible mentorship, collaborations, and is also featured in Stanford News Report tinyurl.com/5e3v8ycs Thanks to co-first author @JianXiong19, @JudithSimcox, and the incredible team at Scenic Biotech.(6/7)
English
1
0
6
431
Kwamina Nyame
Kwamina Nyame@Tyfic_Gh·
Big News: Thrilled to share that my latest PhD work is now published in @Nature. We identify PLA2G15 as the lysosomal BMP hydrolase and show that blocking it improves outcomes in a severe neurodegenerative disease model. Read the article here tinyurl.com/3b9zt5fw (1/7)
English
11
39
175
18.3K
Kwamina Nyame retweetledi
Judith Simcox PhD
Judith Simcox PhD@JudithSimcox·
Absolutely beautiful work @abu_remaileh and @Tyfic_Gh that will be important for #lysosomal storage disorders and in understanding the regulation of BMP lipids. Definitely a tour de force to probe lysosomal biology!
Kwamina Nyame@Tyfic_Gh

Very excited to share our recent discovery of PLA2G15 as a lysosomal BMP hydrolase whose targeting ameliorates lysosomal disease. We establish the rules that govern BMP catabolism, a key lipid implicated in multiple neurodegenerative diseases and lysosomal disorders @abu_remaileh

English
0
1
15
2.5K
Kwamina Nyame retweetledi
Jian Xiong (熊剑)
Jian Xiong (熊剑)@JianXiong19·
Excited to share our comprehensive work on BMP catabolism and truly grateful of the enjoyable journey of this discovery with my great science buddy Kwamina Nyame @Tyfic_Gh and my wonderful mentor Monther Abu-Remaileh @abu_remaileh
English
1
1
8
891
Kwamina Nyame
Kwamina Nyame@Tyfic_Gh·
Very excited to share our recent discovery of PLA2G15 as a lysosomal BMP hydrolase whose targeting ameliorates lysosomal disease. We establish the rules that govern BMP catabolism, a key lipid implicated in multiple neurodegenerative diseases and lysosomal disorders @abu_remaileh
bioRxiv@biorxivpreprint

PLA2G15 is a Lysosomal BMP Hydrolase with Ester Position Specificity and Its Targeting Ameliorates Lysosomal Disease biorxiv.org/cgi/content/sh… #bioRxiv

English
3
18
85
30.1K
Kwamina Nyame
Kwamina Nyame@Tyfic_Gh·
@UcheMedoh Congrats Uche! I know you’ll make great discoveries in your new endeavors
English
0
0
1
243
Uche Medoh
Uche Medoh@UcheMedoh·
Grateful to announce the opening of my lab at the Arc Institute as an Arc Science Fellow! My interdisciplinary team will demystify the role of anti-aging metabolites in aging and age-related diseases for the development of ‘metabolite-inspired’ treatments.
Arc Institute@arcinstitute

💡Early career scientists explore their most curious + innovative ideas at Arc as Science Fellows. New Fellow @UcheMedoh joins us with a background in investigating the molecular mechanisms of anti-aging metabolites for human health and disease. 🧵

English
16
27
316
66.7K

Keşfet

@abu_remaileh @karagm2009 @MargolisLabNYU @NYUPainResearch @nyuniversity @NYUDental @NYULH_DeptofMed @Westlake_Uni