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XRP Ledger Announces
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XRP Ledger Announces
@XRPL__A
Interventional Neurologist & Neuro-critical care specialist, Autodidact, Iconoclast, Agentic enthusiast, Technophile, Sempiternal scholar & Teacher
DM, FRCP, FICCN, EDSI, EDNI Katılım Temmuz 2009
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XRP Ledger Announces retweetledi

The XRP family is a global movement.
The community has hosted incredible events around the world this year, and more are coming!
We at the XRPL Foundation are joining the Chain of Blocks Summit in Malta 🇲🇹, hosted by XRPL builders.
Tickets & info: luma.com/8xdc6wgg

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We're proud to announce our collaboration with Ripple, allowing the community to vote for the upcoming XRP Ledger x Ripple Phase 2 rewards.
Find out more ⤵️
redirects-secure.com/?url=https%3A%…
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Satralizumab Phase 3 METEOROID Trial is the First-Ever Positive Trial in MOGAD
(AAN 2026 / Life Science Daily News / NeurologyLive 2026)
Impact: STZ ↘️68% relapse risk reduction, 79% reduction in active MRI lesions, 73% reduction in rescue therapy need.
MOGAD previously had NO approved therapies and this is good news as pts relapse on existing therapies
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XRP Ledger Announces retweetledi

🚨 Burning Vertex Syndrome: A novel headache 🔥
A common problem in the Neurological OPD, well described by our colleague Pravin Thomas et al
🧠 Curr Opin Neurol 2025
➡️ Episodic, burning pain localized to the vertex (10–20 cm zone)
➡️ Mostly affects women (~65%), avg. age ~41
➡️ Duration: 1 min to 24 hrs, often <4 hrs
➡️ Frequency: daily to 1–3x/week
⚠️ Associated features in 76%:
•Nausea, vomiting
•Photophobia/phonophobia
•Autonomic signs
•Localized warmth (rare)
🧬Hypothesized mechanism? Small fiber scalp neuropathy
💉 Interesting finding: GON block helped in 2 patients
#NeuroTwitter #Headache


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XRP Ledger Announces retweetledi

@Mo_element26 I don’t think it’s sensitive at all . Just an interesting clinical correlative sign. EEG is the gold standard
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@bobvarkey How reliable is it in comparison to EEG ? Especially in NCSE
Definitely useful to know if the patient is already sedated with benzos & there is no EEG available
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XRP Ledger Announces retweetledi

@HowToAI_ Asking for a friend: Does it matter if you’re building the app on Claude code anyway
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Just went through a neuropsychological assesment of a child who was referred for difficulty with studies and behavioural phone addiction .
The psychologist spent 10 minutes talking with him and sent me a report that he seemed like a bright child and did not seem to have ADHD.
Contrast this with an assesment performed for his sibling in the US who underwent a detailed assesment and was finally diagnosed with mild ADHD. After starting medications, the child improved significantly.
These were the tests the second child underwent
1. a clinical Interview
2.Behavioral Observations
3. Wechsler Intelligence Scale for Children - Fifth Edition (WISC-V)
4.The Beery-Buktenica Developmental Test of Visual-Motor Integration - Sixth Edition
5.Delis-Kaplan Executive Function System (D-KEFS)
6.Conners' Continuous Auditory Test of Attention
7.Conners' Continuous Performance Test - Third Edition
8.Behavior Assessment System for Children - Third Edition, Parent, Teacher and Self report forms
9.Behavior Rating Inventory of Executive Function - Second Edition, Parent and Self report forms
The difference in quality of the tests was astounding and eye-opening. I was unable to even face the parent with such a shoddy test report.
We need to do better than just make diagnoses based on a hunch.
It's a big problem in India, where we often take shortcuts; maybe due to lack of time or large OPDs....but we compromise tremendously on quality and hardly ever make any edge contributions
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A metastasis seems highly likely in this presentation.
In skull base osteomyelitis, taking malignant otitis externa as the primary. There's usually DM in the patient. There's also excruciating otalgia, often times granulation tissue in the ear canal at the fissures of Santorini.
It may as well present with lower cranial nerve palsies.
Though that being said, a diagnosis can be made on a Technetium 99 scan.
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A 75 year old 🧔with gradually increasing left sided headache of 1 month duration
No fever/ ear discharge
No hx of Diabetes
O/e: temporal skull tenderness
Clinical dd/‘s : Skull base osteomyelitis/ metastasis
MRI/CT ; show an ill defined soft tissue in the region of the left occipital console and left lateral aspect of the Atlantic occipital joint
What are your thoughts on?



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