Zak Doric, PhD

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Zak Doric, PhD

Zak Doric, PhD

@zakdoric

Investment Partner @a16z bio+health 🧬

SF Katılım Kasım 2017
605 Takip Edilen931 Takipçiler
Zak Doric, PhD retweetledi
Vineeta Agarwala
Vineeta Agarwala@vintweeta·
This is an outstanding AI product that every curious scientist and biomedical researcher should try out Biomni Lab is available for free: biomni.phylo.bio What I love most about Biomni Lab is that it leverages LLMs trained on public data (eg Claude) but also creates a (secure) environment for local reinforcement learning, in which your AI agents can get smarter as they learn from the results of *your* own most recent experiments, your study conditions, the private datasets you upload, etc. Tools, algos, and methods specific to biomed research (eg say a new algo for gRNA design) are fully integrated — and can keep getting better — within the environment too. Basically what every science lab should *wish* they had... Congrats to the truly cracked team of @KexinHuang5 @YuanhaoQ @jure and @lecong! I've known some of this team since our lab days together at @broadinstitute and can personally confirm that they (and I'm sure their army of AI agents 🤖) are a team that won’t rest until they’ve made their mark on the process of science Go @phylo_bio! And thanks to my partners @JorgeCondeBio @zakdoric for bringing @a16z into this exciting effort.
Kexin Huang@KexinHuang5

Today we’re launching Phylo, a research lab studying agentic biology, backed by a $13.5M seed round co-led by @a16z and @MenloVentures / Anthology Fund @AnthropicAI. We’re also introducing a research preview of Biomni Lab, the first Integrated Biology Environment (IBE), where we’re imagining a new way biologists work. Biomni Lab uses agents to orchestrate hundreds of biological databases, software tools, molecular AI models, expert workflows, and even external research services in one workspace, supporting research end-to-end from question to experiment to result. Agents handle the mechanics, while you define the question, then review, steer, and decide. Scientists end up spending more time on science: asking questions, understanding mechanisms, and eliminating diseases. Phylo (@phylo_bio) is a spin-out of @ProjectBiomni, where we will maintain the open-source community and push open-science research. I’m grateful to continue building with my co-founders @YuanhaoQ @jure @lecong and the dream founding team @serena2z @TianweiShe @huangzixin20151 @gm2123 @margaretwhua @malayhgandhi. We’re also fortunate to be advised by leading scientists @zhangf, Carolyn Bertozzi, and @fabian_theis, and supported by an amazing group of investors including @JorgeCondeBio @zakdoric Matt Kraning @ZettaVentures @dreidco @conviction @saranormous @svangel @valkyrie_vc and others. Biomni Lab is available for free today: biomni.phylo.bio Learn more in our launch post: phylo.bio/blog/company-f… We are also hosting launch events - join us at South San Francisco: luma.com/n8k8qb0n Virtual: luma.com/l5ryjaij We’re also hiring! phylo.bio/careers

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Zak Doric, PhD retweetledi
a16z
a16z@a16z·
Biology today is fragmented across PDFs, spreadsheets, and databases. Humans stitch results together manually, often irreproducibly. Designers got Figma. Analysts got Excel. Software engineers got IDEs. It’s time biologists get tools that reflect the way science actually works. @phylo_bio is building the first “Integrated Biology Environment” (IBE) – a single place where hypotheses are generated, experiments are planned, data is analyzed, models are run, and results are produced in a way that’s auditable and reproducible. Phylo’s cofounders Kexin Huang and Yuanhao Qu are the team for this problem: Kexin has spent close to a decade pursuing an “AI scientist” since before the category was defined, and Yuanhao has deep domain expertise in experimental and computational biology. Together they built Biomni – a popular open-source biomedical research agent that became the first concrete step toward Phylo’s IBE platform. Today they’re releasing Biomni Lab, an enterprise-grade environment built on the foundation of Biomni ready for production scientific use. We’re proud to co-lead Phylo’s $13.5M seed round and partner with a team uniquely suited to build a native environment for scientific discovery – an AI scientist built by and for scientists. By @JorgeCondeBio and @zakdoric @KexinHuang5 @YuanhaoQ
a16z tweet media
Kexin Huang@KexinHuang5

Today we’re launching Phylo, a research lab studying agentic biology, backed by a $13.5M seed round co-led by @a16z and @MenloVentures / Anthology Fund @AnthropicAI. We’re also introducing a research preview of Biomni Lab, the first Integrated Biology Environment (IBE), where we’re imagining a new way biologists work. Biomni Lab uses agents to orchestrate hundreds of biological databases, software tools, molecular AI models, expert workflows, and even external research services in one workspace, supporting research end-to-end from question to experiment to result. Agents handle the mechanics, while you define the question, then review, steer, and decide. Scientists end up spending more time on science: asking questions, understanding mechanisms, and eliminating diseases. Phylo (@phylo_bio) is a spin-out of @ProjectBiomni, where we will maintain the open-source community and push open-science research. I’m grateful to continue building with my co-founders @YuanhaoQ @jure @lecong and the dream founding team @serena2z @TianweiShe @huangzixin20151 @gm2123 @margaretwhua @malayhgandhi. We’re also fortunate to be advised by leading scientists @zhangf, Carolyn Bertozzi, and @fabian_theis, and supported by an amazing group of investors including @JorgeCondeBio @zakdoric Matt Kraning @ZettaVentures @dreidco @conviction @saranormous @svangel @valkyrie_vc and others. Biomni Lab is available for free today: biomni.phylo.bio Learn more in our launch post: phylo.bio/blog/company-f… We are also hosting launch events - join us at South San Francisco: luma.com/n8k8qb0n Virtual: luma.com/l5ryjaij We’re also hiring! phylo.bio/careers

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Kexin Huang
Kexin Huang@KexinHuang5·
We’re thrilled to have a16z co-lead our round. It’s been a pleasure (and a lot of fun) working with @JorgeCondeBio, @zakdoric, and the rest of the team. Excited to join the a16z fam!
a16z@a16z

Biology today is fragmented across PDFs, spreadsheets, and databases. Humans stitch results together manually, often irreproducibly. Designers got Figma. Analysts got Excel. Software engineers got IDEs. It’s time biologists get tools that reflect the way science actually works. @phylo_bio is building the first “Integrated Biology Environment” (IBE) – a single place where hypotheses are generated, experiments are planned, data is analyzed, models are run, and results are produced in a way that’s auditable and reproducible. Phylo’s cofounders Kexin Huang and Yuanhao Qu are the team for this problem: Kexin has spent close to a decade pursuing an “AI scientist” since before the category was defined, and Yuanhao has deep domain expertise in experimental and computational biology. Together they built Biomni – a popular open-source biomedical research agent that became the first concrete step toward Phylo’s IBE platform. Today they’re releasing Biomni Lab, an enterprise-grade environment built on the foundation of Biomni ready for production scientific use. We’re proud to co-lead Phylo’s $13.5M seed round and partner with a team uniquely suited to build a native environment for scientific discovery – an AI scientist built by and for scientists. By @JorgeCondeBio and @zakdoric @KexinHuang5 @YuanhaoQ

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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
@KexinHuang5 @JorgeCondeBio We’re honored to be partnering with you and the Phylo team. Excited to see Phylo and Biomni Lab become a core part of how scientists do their work!
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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
Designers have Figma. Analysts have Excel. Engineers have IDEs. Biology never got its equivalent. That’s why we @a16z are proud to co-lead @phylo_bio’s $13.5M seed round to build a native environment for scientific discovery — an AI scientist built by and for scientists. For years, leaders at the frontier AI labs have said AI’s biggest impact will be in science. We agree. But the scientific method doesn’t fit cleanly into a chat window. Phylo is building the Integrated Biology Environment (IBE) — an agentic orchestration layer that coordinates tools, data, and models across the scientific workflow, with the scientist firmly in control. As PhD students at Stanford, Phylo co-founders @KexinHuang5 and @YuanhaoQ built @ProjectBiomni, an open-source biomedical research agent that spread organically across academia, hospitals, biotech, and pharma, and is now used in 7,000+ labs. Today, they’re announcing Biomni Lab, a commercial-grade, enterprise-ready evolution of that foundation. We believe Biomni Lab can become the default landing page for scientific work, the one tab that stays open on every scientist’s laptop. @JorgeCondeBio @daisydwolf @jayrughani Eva Steinman @a16zBioHealth Matt Kraning @MenloVentures @AnthropicAI
Zak Doric, PhD tweet media
Kexin Huang@KexinHuang5

Today we’re launching Phylo, a research lab studying agentic biology, backed by a $13.5M seed round co-led by @a16z and @MenloVentures / Anthology Fund @AnthropicAI. We’re also introducing a research preview of Biomni Lab, the first Integrated Biology Environment (IBE), where we’re imagining a new way biologists work. Biomni Lab uses agents to orchestrate hundreds of biological databases, software tools, molecular AI models, expert workflows, and even external research services in one workspace, supporting research end-to-end from question to experiment to result. Agents handle the mechanics, while you define the question, then review, steer, and decide. Scientists end up spending more time on science: asking questions, understanding mechanisms, and eliminating diseases. Phylo (@phylo_bio) is a spin-out of @ProjectBiomni, where we will maintain the open-source community and push open-science research. I’m grateful to continue building with my co-founders @YuanhaoQ @jure @lecong and the dream founding team @serena2z @TianweiShe @huangzixin20151 @gm2123 @margaretwhua @malayhgandhi. We’re also fortunate to be advised by leading scientists @zhangf, Carolyn Bertozzi, and @fabian_theis, and supported by an amazing group of investors including @JorgeCondeBio @zakdoric Matt Kraning @ZettaVentures @dreidco @conviction @saranormous @svangel @valkyrie_vc and others. Biomni Lab is available for free today: biomni.phylo.bio Learn more in our launch post: phylo.bio/blog/company-f… We are also hosting launch events - join us at South San Francisco: luma.com/n8k8qb0n Virtual: luma.com/l5ryjaij We’re also hiring! phylo.bio/careers

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Zak Doric, PhD retweetledi
Zak Doric, PhD
Zak Doric, PhD@zakdoric·
Really enjoyed our conversation with the @boltz_bio team on the @a16z podcast, especially their perspective on the value of open science, and what it means to build products in the age of AI. Links below for those curious 👇 cc @JorgeCondeBio
Gabriele Corso@GabriCorso

It was fun chatting with Jorge and Zak from Andreessen Horowitz about Boltz, our origin, mission, and the recent launch: - Spotify: open.spotify.com/episode/02sIqV… - Apple: podcasts.apple.com/us/podcast/bui… - YouTube: youtu.be/cBw2V3FiRxs

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Zak Doric, PhD retweetledi
Jorge Conde
Jorge Conde@JorgeCondeBio·
Announcing our newest @a16zBioHealth fund: $700M to back the best founders working to make better medicines and to make the practice of medicine better. To cure disease, to care for our sick, to fix what’s broken is deeply ingrained; it is medicine’s highest aim. “At @a16z, we believe that the best thing that a society can do for a person is to give them a chance. Give them a shot at a great life…” - @bhorowitz @vintweeta @julesyoo @BenPortney @Bryan__Faust @zakdoric @JayRughani @daisydwolf @janerheetweets Michael Cialone, Eva Steinman
Jorge Conde tweet media
a16z@a16z

At Andreessen Horowitz, we just raised over $15B. With these new funds including American Dynamism ($1.176B), Apps ($1.7B), Bio + Health ($700M), Infrastructure ($1.7B), Growth ($6.75B), and other venture strategies ($3B), we raised over 18% of all venture capital dollars allocated in the United States in 2025. Why did we raise the money and how do we plan to invest it? Read more from Ben Horowitz: a16z.news/p/we-raised-15…

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Gabriele Corso
Gabriele Corso@GabriCorso·
Incredibly honored to be part of the @a16z family! From the start, we saw @boltz_bio as a frontier technology company at the service of every scientist. And no better team combines the experience supporting great technology companies with a deep understanding of the space than that of @JorgeCondeBio @zakdoric @JayRughani @Bryan__Faust team at a16z! Ad majora! 🚀🧬
Zak Doric, PhD@zakdoric

Today, we @a16z are proud to announce that we’re co-leading the $28M seed round for @boltz_bio, an applied AI research lab building biomolecular foundation models and infrastructure for real-world drug discovery workflows. Boltz began as a research project at MIT by @GabriCorso, @jeremyWohlwend, and Saro Passaro. In a field where academic tools typically diffuse slowly, their open-source models (Boltz-1, Boltz-2, BoltzGen) achieved rapid, industry-wide adoption and today have been used by over 100,000 scientists, every top 20 pharma company, and thousands of biotechs. Today, they’re announcing the next step: Boltz Lab, a platform built on that proven foundation, including a new generation of small molecule and protein design agents, and designed for real bio/chem workflows. It’s already being deployed with select partners, including @pfizer. The team will also be hosting a series of launch events across multiple cities to share Boltz Lab with the broader research community. (Link to SF event on Jan 15th: luma.com/yogmbte1) We’re excited to support the team as they continue to push the frontier of what’s possible in molecular design and maintain their commitment to open science. Lastly, Boltz is looking for exceptional AI and engineering talent to join them in their mission. Please reach out if that’s you. jobs.gem.com/boltz a16z podcast: open.spotify.com/episode/02sIqV… Endpoints coverage by @AndrewE_Dunn: endpoints.news/exclusive-bolt… Pfizer collaboration PR: prnewswire.com/news-releases/… @JorgeCondeBio @JayRughani @Bryan__Faust @a16zBioHealth @ElliotHershberg @AmplifyPartners @dhaliwas @dreidco @ZettaVentures

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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
@GabriCorso @a16z @boltz_bio We’re honored to be alongside you and the Boltz team on this journey. Excited to see the impact Boltz will have for scientists everywhere.
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Zak Doric, PhD retweetledi
a16z
a16z@a16z·
We’re excited to announce that we’re co-leading a $28M Seed round in Boltz PBC. @boltz_bio comes out of research at MIT from Gabriele Corso, Jeremy Wohlwend, and Saro Passaro. They’ve built frontier open-source AI models for biomolecular research that saw explosive growth in usage among scientists, which is especially impressive for a project out of academia. Their models have been used by over 100,000 scientists, every top 20 pharma company, and thousands of biotechs. Now, the team is going all in on scaling their proven ability to develop cutting edge models with the infrastructure and product sense to make them usable in the lab. Their Boltz Lab platform provides deployment-ready infrastructure that integrates models with proprietary generative AI workflows, intuitive user interfaces and high-performance compute. Boltz Lab is now available and is already being used by partners like @pfizer. By @JorgeCondeBio and @zakdoric @GabriCorso @jeremyWohlwend
a16z tweet media
Gabriele Corso@GabriCorso

Big news from Boltz today: we’re launching Boltz Lab, a new platform with new small-molecule + protein design agents, announcing Boltz PBC and a $28M seed round, and sharing a multi-year partnership with Pfizer. More below! 🚀

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Zak Doric, PhD retweetledi
Jorge Conde
Jorge Conde@JorgeCondeBio·
We’re co-leading @Boltz_Bio’s $28M seed round to make frontier biomolecular AI universally accessible to every scientist working in industry or academia, in labs large or small. Boltz started as a research project at @MIT from @GabriCorso, @jeremyWohlwend + Saro Passaro. Their popular open source models are widely used by scientists. Now they’re expanding from research project to commercial product. Their Boltz Lab platform provides deployment-ready infrastructure that integrates models with proprietary generative AI workflows, intuitive user interfaces and high-performance compute. Boltz Lab is now available + already used by partners like @pfizer. And remaining true to their roots, Boltz PBC will continue to release best-in-class open-source models. @a16z is thrilled to partner with @AmplifyPartners + @ZettaVentures to support Boltz’s mission. @zakdoric  @ElliotHershberg @dhaliwas @dreidco @JayRughani @Bryan__Faust
Jorge Conde tweet media
Gabriele Corso@GabriCorso

Big news from Boltz today: we’re launching Boltz Lab, a new platform with new small-molecule + protein design agents, announcing Boltz PBC and a $28M seed round, and sharing a multi-year partnership with Pfizer. More below! 🚀

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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
Today, we @a16z are proud to announce that we’re co-leading the $28M seed round for @boltz_bio, an applied AI research lab building biomolecular foundation models and infrastructure for real-world drug discovery workflows. Boltz began as a research project at MIT by @GabriCorso, @jeremyWohlwend, and Saro Passaro. In a field where academic tools typically diffuse slowly, their open-source models (Boltz-1, Boltz-2, BoltzGen) achieved rapid, industry-wide adoption and today have been used by over 100,000 scientists, every top 20 pharma company, and thousands of biotechs. Today, they’re announcing the next step: Boltz Lab, a platform built on that proven foundation, including a new generation of small molecule and protein design agents, and designed for real bio/chem workflows. It’s already being deployed with select partners, including @pfizer. The team will also be hosting a series of launch events across multiple cities to share Boltz Lab with the broader research community. (Link to SF event on Jan 15th: luma.com/yogmbte1) We’re excited to support the team as they continue to push the frontier of what’s possible in molecular design and maintain their commitment to open science. Lastly, Boltz is looking for exceptional AI and engineering talent to join them in their mission. Please reach out if that’s you. jobs.gem.com/boltz a16z podcast: open.spotify.com/episode/02sIqV… Endpoints coverage by @AndrewE_Dunn: endpoints.news/exclusive-bolt… Pfizer collaboration PR: prnewswire.com/news-releases/… @JorgeCondeBio @JayRughani @Bryan__Faust @a16zBioHealth @ElliotHershberg @AmplifyPartners @dhaliwas @dreidco @ZettaVentures
Zak Doric, PhD tweet media
Gabriele Corso@GabriCorso

Big news from Boltz today: we’re launching Boltz Lab, a new platform with new small-molecule + protein design agents, announcing Boltz PBC and a $28M seed round, and sharing a multi-year partnership with Pfizer. More below! 🚀

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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
One of our stealth bio/AI companies @a16z is hiring a backend/infra engineer to help build AI agents designed to 100x productivity for biologists. Rare opportunity to join a special team -- feel free to DM me if someone great comes to mind.
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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
absolute tour de force from the Boltz team. so cool to see how you can train a model to learn structure prediction and design jointly--a big step toward more general, physics-grounded generative design. the amount of wet-lab validation across modalities in this release is bananas. and even cooler that they’re open-sourcing BoltzGen for the whole community to build on. huge kudos to @HannesStaerk, @GabriCorso, @jeremyWohlwend, @pas_saro, and the rest of the Boltz team!
Hannes Stark@HannesStaerk

Excited to release BoltzGen which brings SOTA folding performance to binder design! The best part of this project has been collaborating with many leading biologists who tested BoltzGen at an unprecedented scale, showing success on many novel targets and pushing its limits! 🧵..

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Zak Doric, PhD
Zak Doric, PhD@zakdoric·
Incredible energy in the room for the AI Scientist at #SFTechWeek. The concept only re-emerged in broader public conversation a couple of years ago -- and it’s now taking off fast. You can feel a new ecosystem forming in real time around biomedical AI agents, lab automation, data generation at scale, and AI-enabled research workflows. I had fun discussing it with @a16z founders @jacobborrajo, @daashu and @Just_Joshing, and with Stefano from @FenwickWest A new layer of the biopharma stack is taking shape.
Tech Week@Techweek_

Let's talk about the “Rise of the AI Scientist” w/ @a16z + @FenwickWest and unpack how AI agents + platforms are transforming biotech. w/ @zakdoric @jacobborrajo @daashu @Just_Joshing and Stefano Quintini from Fenwick #SFTechWeek

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