Fern Koay 郭

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Fern Koay 郭

Fern Koay 郭

@_fernace

👩🏼‍🔬🇲🇾🇦🇺🇺🇲🔬 Scientist in immunology @TheDohertyInst @UnimelbMDHS

Melbourne, Victoria Katılım Ekim 2014
377 Takip Edilen670 Takipçiler
Fern Koay 郭 retweetledi
Prof Paul Beavis
Prof Paul Beavis@paulbeavis4·
We are looking for a Project Manager to facilitate a new program of work centered around a novel CAR T technology that will lead to a phase I trial & development of novel assets. Please see details below for role description and for further details.
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Fern Koay 郭 retweetledi
CD1-MR1 Immunology
CD1-MR1 Immunology@CD1MR1·
Our third webinar from the AUS/APAC region, will feature Nick Gherardin and Sho Yamasaki. Thursday, June 12th at 17:00 AEST (8:00 London, 16:00 Tokyo). If you'd like to keep up to date, sign up to the mailing list here: cd1mr1.com/cd1-mr1-society
CD1-MR1 Immunology tweet media
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Fern Koay 郭 retweetledi
CD1-MR1 Immunology
CD1-MR1 Immunology@CD1MR1·
Our second webinar hosted from USA, will be by Laurent Gapin and Antonia Rotolo. Thursday, February 6th at 16:00 GMT (8:00 Pacific, 11:00 Eastern, 1:00 Friday Tokyo) If you haven't join, get updates and link here: cd1mr1.com/cd1-mr1-society
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Fern Koay 郭 retweetledi
Wael Awad
Wael Awad@WaelAwadMoh·
Sharing our latest work @PNASNews MR1 presents vitamin B6–related compounds for recognition by MR1-reactive T cells We postulate that tumours' increased metabolism of vit B6 leads to elevated levels of pyridoxal and preferential recognition of tumours by pan-cancer T cells see 🧵
Wael Awad tweet media
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Fern Koay 郭
Fern Koay 郭@_fernace·
We're incredibly stoked and honoured to have Fabio Grassi's commentary on our paper - this work has built on many of his team's findings and body of work, in the nexus of purinergic control of T cell activation and function! 🌟
Journal of Experimental Medicine@JExpMed

Grassi @LaStatale discusses new study by Xu, @_fernace et al (hubs.la/Q02YM3m20) which defines NAD-induced cell death via purinergic P2RX7 receptor in type 1 unconventional T cells, particularly intrahepatic MAIT cells pivotal in liver homeostasis hubs.la/Q02YMplz0

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Fern Koay 郭
Fern Koay 郭@_fernace·
@BjrnRissiek @JExpMed definitely an extension of the work with lots of ref'd papers from you and colleagues, thanks Björn!
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Björn Rissiek
Björn Rissiek@BjrnRissiek·
@_fernace @JExpMed Congratulations! Great work and great to see that the issue of cell preparation related NICD is addressed by more and more groups in the field of lymphocyte biology 😃
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Fern Koay 郭
Fern Koay 郭@_fernace·
Sharing our latest work @JExpMed! We've uncovered that P2RX7 regulates unconventional T cells selectively, particularly subsets that co-produce IFN-γ & IL-4. Hoping this helps more discoveries in the role of these innate-like cells, using inhibitors from the P2RX7/ARTC2 field!
Rockefeller U. Press@RockUPress

In @JExpMed, Xu, @_fernace et al. @TheDohertyInst reveal that the ARTC2–P2RX7 regulatory axis is a key modulator of unconventional T-cell survival, showing how this pathway selectively influences innate-like, IFN-γ and IL-4 co-producing T cells. hubs.la/Q02YMvMt0

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Fern Koay 郭
Fern Koay 郭@_fernace·
Conceptually, non-peer review'd diagram here: Within T cells at least, integrating thoughts posed by labs of P.Brennan, B.Jabri, perhaps the extent of tissue damage sensitivity could be a hallmark of the ‘T cell-innateness’ theory. tinyurl.com/ycy6dv24 tinyurl.com/bd6kxekk
Fern Koay 郭 tweet media
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Keşfet

@Lynette_Beattie @TheRMH @TheDohertyInst @PNASNews @BjrnRissiek @JExpMed @HBorgesdaSilva @LMackayLab