Alien Operator

The bond market will reveal everything that the news and the wealthy are attempting to conceal from you.

A Stanford psychologist spent 4 years proving that the simple act of walking generates 60% more creative ideas than sitting, and the experiment she designed to kill every alternative explanation is one of the most decisive findings in modern psychology. Her name is Marily Oppezzo. She got the idea for the study while walking with her advisor at Stanford to discuss her thesis topic, and the paper she eventually published in the Journal of Experimental Psychology in 2014 is sharp enough that it should have ended the seated meeting on the day it came out. She ran 4 experiments on 176 people. Same person tested twice. Once sitting, once walking. The creativity tasks were the standard ones psychologists have used for decades to measure how good a brain is at generating novel useful ideas. The result was almost too clean to publish. 81% of participants in the first experiment produced more creative ideas while walking than while sitting. In the second experiment, 88%. In the third, 100%. Every single person walked into a more creative version of themselves. On average, people generated 60% more novel useful ideas the moment their legs started moving. The skeptical question is the obvious one. Maybe it was the fresh air. Maybe it was the scenery passing by. Maybe it was the change of environment doing the work, not the walking itself. Oppezzo killed every one of those explanations with one experimental decision. She put people on a treadmill facing a blank wall. No scenery. No fresh air. No environmental change. Just legs moving in place while staring at white drywall. The 60% boost held. Then she ran the experiment that closed the case completely. She took participants outside in two conditions. Half of them walked through a Stanford courtyard. The other half were pushed through the exact same courtyard in a wheelchair. Same outdoor stimulation. Same scenery passing at the same speed. The only difference was whether the legs were moving. The walkers produced dramatically more novel high-quality ideas than the wheelchair group. The outdoors did almost nothing on its own. The walking did everything. This is the part of the study that hit hardest when I read it the first time. She also tested the opposite kind of thinking. Convergent thinking. The kind where there is one right answer and you have to narrow down to it. Word puzzles where 3 words share a hidden fourth word that connects them. The seated participants did slightly better on these. Walkers got slightly worse. Walking is not a general intelligence enhancer. It does one specific thing. It opens up the divergent search inside your brain. The part that generates options. The part that produces unexpected connections. The part that takes a problem and finds five ways into it instead of one. When you need to converge on the single right answer, sit down. When you need to find the answer in the first place, get up. The mechanism is now well understood. Walking selectively activates what neuroscientists call the default mode network, the system inside your brain that runs when you are not consciously focused on anything. The DMN is where mind-wandering happens. Where memories cross-reference each other. Where ideas that have been sitting in separate folders inside your head finally bump into each other. When you sit at a desk and force yourself to concentrate, you suppress the DMN. When you walk at a natural pace, the executive part of your brain gets just busy enough handling the walking that the DMN comes online and starts doing the work that focus was blocking. The most useful finding in the entire paper is the one almost nobody quotes. The boost did not turn off the moment people stopped walking. Participants who walked first and then sat back down stayed elevated. Their next round of seated creativity work was still significantly better than people who had been sitting the whole time. The rest lingered for at least several minutes after the legs stopped moving. You do not need to do creative work while walking. You need to walk before the creative work. The brain holds the state. The history of this is the part that should haunt anyone who still does meetings in chairs. Charles Darwin built a gravel loop behind his house in Kent called the Sandwalk and walked it 3 times a day for the rest of his life. The theory of evolution was developed one lap at a time on that path. Nietzsche walked up to 10 hours a day during the years he wrote his most important books and openly said the work was conceived on his feet. Beethoven composed for the morning and walked for 5 hours every afternoon with a pencil in his pocket for when something landed. Kahneman said the best thinking of his Nobel Prize-winning career happened on leisurely walks with Amos Tversky. Steve Jobs refused to take important conversations sitting down. He held them on foot. Every one of them was using the system Oppezzo would not measure until 2014. They just did not know what to call it. The question worth sitting with is the one almost nobody asks. Every meeting you have ever attended sitting around a table was a meeting held at a fraction of the brain power that was actually available to the people in the room. Every brainstorm that got stuck inside a conference room. Every problem you tried to solve at a desk and gave up on. Every idea you could not quite get to. The intervention is the easiest one in modern science. No supplement. No app. No subscription. No training program. Just a pair of legs and 15 minutes. The Stanford lab proved it. The philosophers knew it. The neuroscience explains it. And almost everyone reading this is still trying to think their way out of problems sitting completely still.

1/5 I'm a cardiologist. I have spent twenty years watching cholesterol destroy arteries, trigger heart attacks, and kill people I care about. Today, Eli Lilly presented data that may begin to end that era. VERVE-102. A single infusion. One dose. It uses base editing to permanently turn off the PCSK9 gene in your liver. Presented today at the European Atherosclerosis Society Congress: 88% reduction in PCSK9. 62% reduction in LDL cholesterol. Sustained up to 18 months. No treatment-related serious adverse events. One infusion. Not daily pills you forget to take. Not monthly injections. One dose — and your cholesterol may stay low for the rest of your life.

BREAKING. Today in the New England Journal of Medicine: a single IV infusion permanently dropped LDL cholesterol by up to 62%, with effects sustained 18 months and counting. This is the beginning of one-shot gene-editing medicine for heart disease.

It feels very futuristic to imagine a world with one-and-done therapies that lower LDL cholesterol for life, but... it might not be far off! These are new phase 1 data for Verve/Lilly's PCSK9 base editor: one single intravenous infusion reduces LDL cholesterol by as much as 60%

SITUATION DETECTED: Eli Lilly’s one-time gene editing therapy cut LDL cholesterol by 62% in Phase 1 trial participants, with effects lasting up to 18 months. No serious adverse events reported.

Eli Lilly has done it. They've gone and made what seems to be a powerful, permanent gene therapy for LDL cholesterol. That means they'll be able to effectively prevent most heart disease with a single infusion!

Gene editing is finally here. And it's targeting the biggest killer in the world. Heart disease. Eli Lilly $LLY just released data for a gene therapy called VERVE-102. It completely changes how we treat high cholesterol. Instead of taking a pill every day, you get one single IV infusion. The medicine travels directly to your liver. It permanently turns off the specific gene that causes high LDL cholesterol. The early trial results are incredible. Patients experienced a massive 60% drop in their LDL cholesterol. Think about what GLP-1 drugs did for obesity. Five years ago, Ozempic was "just Phase 2 data." People said the side effects were unclear. The long-term outcomes were unknown. Now it's a $50 billion/year drug that changed how we treat obesity. GLP-1s rewrote obesity. VERVE-102 could rewrite heart disease. Medicine is moving faster than most people realize.

WSJ: “Buyers now allocate 42% of their incomes to housing costs, according to the [US] Burns Affordability Index, which is calculated based on a 10% down payment on a median-priced existing home. This is still extremely unaffordable, but better than in late 2023, when the ratio hit 48%.” #economy #markets #housing @WSJ

Adam Hoffman raped his son’s best friend for 3 years First-degree felony. Life without parole. Ken Paxton’s office gutted it to 60 days. He walked free after 30. No sex offender registration. His record scrubbed clean. Texas protects predators with power!

If you see a fox in your neighborhood, be glad. A red fox eats roughly 2,000 mice, rats, and voles a year. They help keep tick-carrying rodent populations in check, which reduces local Lyme disease risk. Don't call animal control. Just watch.

I don’t care what the “official” statistics tell you, when you go to a Home Depot on Memorial Day and you don’t see a single other soul in the entire store, something is wrong with the economy

THIS IS INSANE 🇺🇸 Out of 45 U.S. presidents in history, President Trump is now solely responsible for 27.7% of the national debt.

what in the black mirror episode is this

The President’s Big Beautiful Bill, the Iran War, and Republican spending bills will create a $2 trillion budget DEFICIT in 2026. Financing just the new debt costs more than all federal road & bridge projects, and we will be making those new interest payments each year, forever.

Nothing in this post would be considered “rich.” There are primarily two scenarios where the ultra-rich need to be taxed. 1. When they borrow against their investments and never take a salary or take a minuscule one like Bezos’s $80k annual salary, they forgo a 40% income on 99% of their actual wealth for 3-5% interest rates when their investments return an average of 8%-15%. 2. Wealth tax needs to be reformed due to the numerous loopholes. Currently, the ultra-rich control $55 trillion in wealth. The wealth tax generates $28 billion annually, which is less than 0.05% of the $55 trillion they hold. The wealth tax has essentially been dismantled since the 1990s.

This is where the “tax the rich” crowd lose me. Say I earn 90k a year and in 2027 I inherit $200,000 I invest that $200k and after 10 years in the stock market it’s now worth $400k If I sell it and realise the $200k capital gain, what the govt and the “tax the rich” crowd are saying is that I should be taxed as if I make $290k every year. Now if I try and split that CGT income across 2 people I’m “greedy” and avoiding tax But if I sell down in 4x $100k lots over 4 years and minimise my tax, that’s ok and nobody bats an eyelid - but it’s the same principle.

@lomaxx 400k is no where near the "rich" we talking about. 200 million, yeah, tax that shit. 200k? Keep it all

This should make you sick as an American .

I love Ron Harper Jr 😭

Jaylen Brown was outside smoking hookah on Federal Hill !! Nice to see ! The Man loves Providence !

There are no bigger pigs in all of human history than American corporations.