Amit Jolly

Pretty excited to fuck up leukemias. Data in hand.

The movers and shakers diligence quickly and decide quickly. Collab accordingly.

@howard 🫶

9 years ago today. Lux tried to get me “out” of the TV during the Yext IPO.

Canary Cure Therapeutics’ Raj Reddy and I will be in Boston’s Third Annual GLP-1-Based Therapeutics Summit! April 14-16. Advancing Targeted Genetic Therapies with a Dual-siRNA Approach to Disrupt the Current GLP-1 Monopoly for a More Patient-Focused Treatment Diversity

@LifeSciVC SubQ, once every 6 months

@LifeSciVC Bruce, we have a pipeline of seven siRNA programs. One of which, CCT-217, has better efficacy data than retatrutide in mice models w/ muscle gain. Our CEO & Founder at Canary Cure Therapeutics will be at the GLP-1 Therapeutics summit in boston April 14-16 glp-1-based-therapeutics.com/speaker/dr-raj…

Interesting data from Epic medical records - suggests that for many patients in the "real world", they are able to keep the weight off after stopping GLP1s... epicresearch.org/articles/two-y… #EpicResearch

*Also less transformation to sAML 9/40 patients (~10%) instead of historical 30-40%. Raw data pull. First CMML -> sAML patient living for 14+ mo. Historical is 3 mo survival.

Applying the proposed WHO/ICC 2022 oligomonocytic CMML (O-CMML) criteria, 468 of 1,861 MDS patients (25%) met the new CMML definition and were “re-classified accordingly." Expanding CMML from a niche ~6k market to ~ 60k+ pts ash.confex.com/ash/2024/webpr…

CMML data at Taran Therapeutics w/ lenzilumab + aza. anti-GMCSF mAb. Australian pts. No new CMML drug in 30 years. In 2022, 1/4 of MDS pts reclassified to CMML. A market we thought was 6k is 60k. Also less transformation to sAML 9/40 patients (~10%) instead of historical 30-40%.

Applying the proposed WHO/ICC 2022 oligomonocytic CMML (O‑CMML) criteria, 468 of 1,861 MDS patients (25%) met the new CMML definition and were “re‑classified accordingly.” Expanding CMML from a niche ~6k market to ~60k+ pts ash.confex.com/ash/2024/webpr…

@annikakimc @CNBC congrats!

Thrilled to announce that I’m stepping into an expanded role at @CNBC that includes TV coverage. Alongside my reporting on the pharma industry for CNBC.com, I’ll be covering U.S. health insurers, federal health policy, and drug pricing across our platforms.

@RNAiAnalyst HI Dirk, can we talk? You're gonna like what we're working on at Canary Cure Therapeutics. 347.819.5910

$wve i (virtually) participated in the study just to show you what a 3% smaller waist looks like in real life. I am wearing here the same belt btw.

@chris_sinkey @nightowlai_ @SuperteamUSA Love seeing what the Nightowl AI team is building here. You’re clearly onto something big at the intersection of AI, ownership, and compliant tokenization, and it shows in the traction, patents, and thoughtfulness of the architecture. Chris and Chris are a dynamite team

We've been quietly building something big, integrating AI and tokenization at @nightowlai_ We've raised over $500k with from early adopters using 506(c). We've yet to approach VC. We've been selected as founding members of @SuperteamUSA, the US accelerator for my favorite blockchain - Solana. @NickyScanz @Amystreet are nothing short of legends. We've filed 5 provisional AI architecture patents, authored a technical & strategic 25+ page white paper, built a dazzling deck, and most importantly, an Agent OS system we think adds real value to this world. Our demo, branding, and value prop are all, for lack of a better word, ELECTRIC. Our pitch      --> Comprehensive. Our product --> Easy to use. We're now excited to announce we're opening the raise to qualifying investors for: Nightowl AI @nightowlai_ @ nightowl.com Agent Creation. Tokenized Intelligence. The AI agent labor market where humans own the intelligence. Our mission: To expand human agency over AI. Our vision: We start with why  --> "To amplify creativity and productivity… Explain how      --> …through decentralized ownership over… then what   --> …composable agent intelligence." So what's all that mean, in like, human words? It means we're building an integrated ecosystem to create, publish, and share almost anything using AI, from almost any model. Apps. Websites. Media. Agents. Whole orgs of skilled, permissioned agents (even the NFT-identified decentralized ones) that can take on complex digital work IRL (like humans). All from a neon owl-themed experience designed to inspire. Done creating? Take delivery of your unspent subscription value in the form of a regulatory compliant, US-native digital asset. Your AI value? Owned. Subscription breakage? Unbroken. Costs? Dramatically reduced. AI subscriptions? Consolidated. AI inference is now commoditized at the application layer. The next great use-case for crypto is here, accessed by anyone from normal payment rails. We've integrated 6 legal, technical, and structural innovations to architect a compliant tokenized launch from entirely within the US. We think it’s the first of its kind to pull it all together. I've had to draw from all my experience to get here, from consumer tech, SaaS, media, IT, venture/corp dev, markets, to US and international legal regulatory compliance, and meet a visionary co-founder who's got an insatiable drive to build in @Nightowl_Chris (whom we convinced to finally get on X for this). ----- Reach out. Follow us. Get the pitch. Learn about the opportunity. DD the data room. We've recorded a demo. We've recorded the full pitch presentation. See clips below We're looking to build an amazing community of decentralized owners from day 1. That day is today. Join the journey. DM

@ayalstern @RalphQuintero @openclaw @thelabmiami @jdanjohnson @GianniDalerta ⚡️🙂

Nothing to see here! We are just on vacation here in Miami. @openclaw meetup @thelabmiami

@saif305 @flventure @iconnections_io @thelabmiami @GianniDalerta @RalphQuintero 🕵️‍♂️good 👀

@amitkjolly @flventure @iconnections_io @thelabmiami That’s my primos @GianniDalerta & @RalphQuintero at work!

Miami this week: 📍 2/23–25 — Florida Venture Forum Capital allocators. Founders. Real checks. @flventure flventure.org 📍 2/23–26 — iConnections Global Alts Private equity. Hedge funds. Institutional LPs flying in. @iconnections_io iconnections.io/global-alts-mi… 📍 2/24 — OpenClaw Miami Builders @PurpleHorizons8 luma.com/ddfjmykw 📍 2/25 — Hard Tech War Room Defense. Advanced manufacturing. Real hardware. luma.com/by1tdnwy 📍 2/25 — Generative Gatherings (Miami AI Hub) AI operators actually shipping. @burhansebin luma.com/ibgfb69p 📍 2/27 — Miami Economic Forum Macro. Policy. Capital flows. @EconClubofMiami econclubmiami.org/2026-agenda/ 📍 2/27 — CREW Miami — Data Centers Boom @CREW_Miami_FL miami.crewnetwork.org/events/2026/po… I’m know there are many more events — pls comment and add to this post. In one week: • Venture • Global alternatives • SWF’s • AI • Hard tech • Defense • Macro • Data centers The “there’s no talent” crowd is still arguing on the timeline while LPs, founders, and investors are in the room. Opportunity doesn’t announce itself politely. It compounds quietly.

@saif305 @flventure @iconnections_io ⚡️

@johnnywestt 🔥read

Hi Friends, funeral service this Friday Feb 15, 2026 in Florida. Details keep changing. Please contact me directly for details c. 1.347.819.5910 All are welcome.

Justin Zelin: 10.8.1990 - 2.15.2026. Forever legend.

@PascalUnger @peteryared ⚡️

"Berlin in 1992, SF in 1997. I never thought I'd feel that energy again. Miami in 2026 proved me wrong. It's by far the most interesting city in the Western world to be in atm!" Well said @peteryared 👏