Ángeles Tepper, PhD

Este experimento es una genialidad. 4 niños intentan hacer funcionar aparatos analógicos.

when it's your turn to give lab meeting and you don't have new results to show

𝗜𝗻𝘁𝗲𝗿𝗲𝘀𝘁𝗲𝗱 𝗶𝗻 𝗶𝗻𝘁𝗲𝗿𝘀𝗲𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗰𝗼𝗻𝗰𝗲𝗽𝘁𝘂𝗮𝗹 & 𝗲𝗺𝗽𝗶𝗿𝗶𝗰𝗮𝗹 𝗯𝗿𝗮𝗶𝗻 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵? Some of this year's discussions in Neurosci & Philosophy Salon: Brain networks Consciousness Causation Emergence Mental disorders @neurosciencephilosophysalo5410" target="_blank" rel="nofollow noopener">youtube.com/@neurosciencep…

This is 1 cubic millimeter of the brain. 57,000 cells, 150 million synapses & 230 millimeters of ultrafine veins.

NEW PAPER OUT 🥳 (it's open access) ⭐Longitudinal changes in striatocortical connectivity in first-episode psychosis associated with the emergence of treatment resistance⭐ See the summary figure for more info, or read the full article at: nature.com/articles/s4153…

Registration is still open for #FSLCourse2025. Register now to secure your spot! 💻 Fully online course 🗓️ September 15th-26th 🧠 Lectures & practicals on structural, functional, diffusion and resting state brain image analysis 🔗 open.win.ox.ac.uk/pages/fslcours…

We are in a war of ideas for the future of our nation and our democracy. This is about all of us, but it is not only about us; it is also about those we lift up. So right now, we encourage you to think of whose voices you believe in, that we need to hear from in this moment, if we want to build a democracy and the world we want to live in – we urge you to send them to one of our “Write to Change the World” workshops. It is open to everyone, regardless of identity, position, or means. We seek to over-represent the underrepresented, and scholarships are available for anyone who needs them. Upcoming workshops: 👉🏾 July 16 & 17 (2:00 pm - 5:30 pm ET) 👉🏾 July 24 & 25 (10:00 am - 1:30 pm ET) Register here: theopedproject.org/workshops

Time is ticking! Applications for the 🌍 OxCIN Global Scholars Programme 🌍close on June 30th. Are you an early career researcher from the Global South, interested in online training in MRI physics & analysis using FSL? Apply here: tinyurl.com/255rxr5a Please repost!

How exercise protects the brain through neurovascular-associated astrocytes and neuroplasticity: Results of elegant single cell/nuceli studies in the experimental Alzheimer's model @NatureNeuro nature.com/articles/s4159…

BREAKING: Your brain’s connective tissue isn’t just glue: It’s a switchboard for neuromodulation. We used to think that astrocytes (the beautiful star-shaped glial cells) were the brain’s 'support staff.' But thanks to exciting new work from Guttenplan and colleagues this week in Science, we have more evidence that glia are more than just passive observers. They are active gatekeepers, controlling how brain circuits turn on and off in response to neuromodulators like dopamine, norepinephrine, and glutamate not to mention 'electricity.' Key Points: - The gating is driven by GPCR signaling and internal cell state, not just calcium. - G protein–coupled receptor (GPCR) activity in astrocytes, especially via the dopamine D2 receptor (Dop2R), changes how these cells regulate circuits. - Dopamine responses can be flipped from inhibitory to excitatory via astrocyte control. - Astrocytes can reverse how neurons react to dopamine, dramatically changing behavior in animal models. - These mechanisms are ancient and conserved across species. - From fruit flies to rats, astrocytes play this surprising regulatory role meaning human relevance is likely high. - Glia may hold the key to improving neuromodulation therapies. - By targeting astrocyte gating mechanisms, we might one day use this to fine-tune DBS or pharmacological treatments more precisely and effectively. - The bottom line? Glia are emerging as not just as glue, but as circuit integrators. - Glia could be the secret to unlocking smarter, more personalized neuromodulation. My take: This isn’t just basic science, it’s a potential game changer for how we think about treating Parkinson’s, depression, epilepsy, and beyond. If astrocytes can 'gate' neuron responses, then targeting glia may be the next frontier in brain modulation therapies like deep brain stimulation (DBS), focused ultrasound, or even neuropharmacology. Glial cells, especially astrocytes, aren’t just background noise; they dynamically shape how neurons behave. This study uncovers a 'gating' mechanism, where one neurotransmitter can flip a switch in astrocytes that changes how they respond to other astrocytes and the surrounding brain tissue. The findings are conserved across species: flies, zebrafish, and mammals. This data collectively suggests that incredibly this process likely has a fundamental role in brain evolution and function. Astrocytes are not passive. They actively decide how and when neurons fire. Exposure to neuromodulators like norepinephrine could potentially unlock how the astrocyte respond to other transmitters such as dopamine and glutamate. #GliaMatters #Astrocytes #Neuromodulation #Parkinsons #Neuroscience #DBS #BrainHealth science.org/doi/10.1126/sc… @ParkinsonDotOrg @FixelInstitute

While evidence is increasing that psychedelics offer some benefit, we don’t need to relearn the lessons of the past in relation to psychosis risk. A precision health approach is needed. And what’s almost certain is that these are not for teenagers with developing brains.

MIT University just released free online courses. No payment required. Here are 10 courses you don't want to miss in 2024:

@chorye I have an illustrated repository called “friends don’t let friends make bad graphs”. github.com/cxli233/Friend… Comes with counter-examples, examples, and explanations.

Elsevier is losing editors

Gender inequality is associated with differences between brains of men and women. Study with 7876 fMRI scans from 29 countries. 👏👏 pnas.org/doi/10.1073/pn…

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PhDs have a range of transferable skills but are not taught how to market them. Here are 10 high-value transferable skills:

Intra and inter-individual variability in functional connectomes of patients with First Episode of Psychosis. Great work led by @angietepp (visiting scholar at CONNplexity Lab during 2020/21). With Dr. Nicolas Crossley and team. doi.org/10.1016/j.nicl…

La AI está cambiando el mundo, pero la mayoría no sabe cómo comenzar a utilizarla en su día a día. He estado varios meses buscando las MEJORES herramientas de IA para que tú no tengas que hacerlo. ¡Vamos allá! 10 aplicaciones de IA para hacerte la vida MUCHO más fácil 🧵👇

We are looking for early-career neuroimagers in the Global South to be remotely affiliated with WIN in 2022-23. Join us! Training, networking, collaboration. DEADLINE EXTENDED to September 15. Please R/T. twitter.com/OxfordWIN/stat…