Andreas Pfenning

138 posts

Andreas Pfenning

@apfenning

Assistant Professor of CompBio at Carnegie Mellon University. Working at the intersection of compbio, genomics, neuroscience, and evolution.

Pittsburgh, PA Katılım Aralık 2009

629 Takip Edilen545 Takipçiler

Andreas Pfenning retweetledi

MeloMelo_Coconut@MeloMeloCoconut·2 Oca

#TearsOfThemis X #MeloMelo Collab Event has ended.All the staff at Melomelo extend our sincere gratitude to everyone. Looking forward to joining forces again in the future to create more wonderful moments together. Hope to see you again next time.

Tears of Themis@TearsofThemisEN

#TearsOfThemis X #MeloMelo Collab Event Review Tears of Themis X MeloMelo Collab Event has ended. Thank you for your enthusiastic participation. Hope to see you again next time! #ToTXmas

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Ziheng Chen@chen_ziheng_cmu·20 May

Delivered my debut conference talk at the #KeystoneSymposium on #Neurodegeneration. A heartfelt thanks to Li-Huei Tsai and Aaron Gitler for organizing such a dynamic and insightful conference. Thrilled by the promising advances we're making in understanding #AlzheimersDisease

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Andreas Pfenning@apfenning·12 May

@BenedictPaten @eenork @n8_upham @NCBI @thednazoo @Mammals_Suck @ucscgenomics Amazing!! Beyond any individual conclusion, this resource will transform the way vertebrate evolution is studied.

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Elinor Karlsson (elinork.bsky.social)@eenork·10 May

FOUND Raccoon genome deposited in @NCBI in Feb! ncbi.nlm.nih.gov/assembly/GCA_0… by @thednazoo #Zoonomia includes #OpenData genomes thru 2019 (big data = SO MUCH TIME to analyze) Missing? Many genomes made since then. @BenedictPaten can we have new 🌵 alignment? Meme: @Mammals_Suck

Elinor Karlsson (elinork.bsky.social) tweet media

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Sarah Marzi@sj_marzi·5 May

Super excited to host @BrandonDLe from @jsteinlab next Tuesday at 3pm for the #neurogenomics seminars. Bran will present the lab's excellent recent work linking wnt pathway activation with context specific regulatory QTLs. DM/email for the zoom link

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Andreas Pfenning@apfenning·4 May

Rather than studying evolution based on conservation of specific nucleotides, we using machine learning to find conservation/convergence based on predicted tissue-specific open chromatin across >200 genomes.

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Andreas Pfenning@apfenning·4 May

It was wonderful to be a part of the amazing #zoonomia team! Congrats Irene, @alyssajolawler, and Daniel on the TACIT manuscript as a part of this package.

Science Magazine@ScienceMagazine

Researchers in Science have pinpointed parts of the genome linked to a few exceptional traits in the mammalian world, such as extraordinary brain size, superior sense of smell, and the ability to hibernate during the winter. scim.ag/2tp #Zoonomia

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Science Magazine@ScienceMagazine·27 Nis

The @ZoonomiaProject’s sequencing of more than 240 mammal genomes is paving new roads for understanding mammalian diversity and evolution and ourselves. Learn more in a new special issue of Science: scim.ag/2oO #Zoonomia

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@BaDoiPhan.bsky.social@BadoiPhan·27 Nis

The current issue of Science is out online with a lot of evolutionary genomics from zoonomiaproject.org and the @apfenning lab, a massive effort! On mammals: science.org/doi/10.1126/sc… On humans: science.org/doi/10.1126/sc… On regulatory evolution: science.org/doi/10.1126/sc…

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Ray and Stephanie Lane Computational Biology Dept.@CMUCompBio·27 Nis

As a part of the @ZoonomiaProject, a team of CBD researchers developed the Tissue-Aware Conservation Inference Toolkit to identify genome parts critical to understanding how certain species' traits evolved. Read about it in this month's @ScienceMagazine! cs.cmu.edu/news/2023/zoon…

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Phillip Compeau@PhillipCompeau·27 Nis

It's so cool to see @CMUCompBio colleagues' work on connecting mammalian regulatory regions to phenotype get published in @ScienceMagazine ! Even more exciting is that one of the first authors on this work is our *undergrad* student Daniel Schaffer. Such a huge deal!

Science Magazine@ScienceMagazine

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Martin Jinye Zhang@martinjzhang·22 Nis

Excited to share that I will join @CMUCompBio as a tenure-track assistant professor in fall 2023! I am thrilled about starting this new chapter with my amazing new colleagues. I will work on #GWAS #scRNAseq #eQTL #machinelearning, #AIforScience

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Andreas Pfenning@apfenning·26 Nis

@martinjzhang @CMUCompBio Excited to have you board!!

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Andreas Pfenning@apfenning·12 Oca

Amazing illustration! @davidasinclair, it was wonderful working with you on this project. So excited to see it out.

David Sinclair@davidasinclair

Delighted to share our latest study that tests The Information Theory of Aging. 13 years of work. Available at 11 AM EST today @CellCellPress. What’s it about? Here’s a clue from Catherine Delphia’s illustration in Lifespan

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Erich Jarvis@erichjarvis·4 Kas

Please Vote this cycle in the USA (between now and Nov 8th 2022). Don't let someone else decide your future for you. Vote for those that allow women to choose their future, and that accept the majority of the people's choice, especially when they were not chosen.

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Andreas Pfenning@apfenning·20 Eki

@anshulkundaje Sounds fun! Selfishly focussed on brain/though, though. We think we can do it rare populations without transgenics by combining jneurosci.org/content/40/50/… for isolation with elifesciences.org/articles/69571 for labelling.

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Anshul Kundaje@anshulkundaje·20 Eki

I think we're grossly underestimating the importance of systematically profiling genome wide TF binding in large numbers of cell contexts. With ENCODE ending, are there other efforts doing this on a massive scale? If TF enthusiasts are interested in teaming up, I'm in.

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Rob Waterhouse also @rmwaterhouse.bsky.social@rmwaterhouse·6 Eki

If you missed Gene's inspiring talk you can catch up on the #BG22 platform - a great historical perspective from someone with such experience is a real education ... many researchers working with #genome sequencing data today sometimes forget how far things have come!

Rob Waterhouse also @rmwaterhouse.bsky.social tweet media

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Andreas Pfenning@apfenning·6 Eki

Congrats, Zheng!

CMU Mellon College of Science@CmuScience

.@CMU_Bio professor Zheng Kuang has received a National Institutes of Health Director's New Innovator Award from @NIH_CommonFund to support his research into how intestinal bacteria regulate metabolism and immunity. cmu.edu/mcs/news-event…

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