Guido Appenzeller

@natanielruizg @tkipf Many of the sleep scores/recommendations to me look more like entertainment than anything rooted in medical data. I just know for myself that with 6 hours I am Grumpy and unfocussed. At 7 hours or maybe 7:15 I feel great and have a productive day. Some modifiers apply.

@tkipf @appenz and before you were hitting the required time right? my sleep looks similar to yours :) - except i don't have a kid hahaha

Confession: I never had a single work-related sleepless night or ever pulled an all-nighter during my career incl. PhD. Don’t sacrifice your health. Sleep is a superpower — your brain on 8hrs of sleep is a lot smarter than your brain on sleep deprivation. Don’t listen to people who tell you to chronically sacrifice sleep for work. Sacrificing sleep for your kids/family is a different story.

@natanielruizg @tkipf Same. 7 hours and I am happy and rested.

@tkipf help i can’t even sleep 8 hours when i try to

@EBorgnia @relace_ai Congratulations!

Today we're launching Jacq. A coding agent built together with the small models we've been training at @relace_ai for the past 1.5 years. It runs entirely in the cloud, and decides when to pull context from any of your connected devices. It uses all the software you already live in: Slack, Linear, GitHub, email, etc. Plus, threads are now durable — a real record of how work happened. Just drag them into a new chat to get context for your next task.

Cost is a huge issue for coding models today. Great to see Relace with their expertise in training small models joining the party!

@PalgunaShetty Umm.. No. Spam processing happens early in the mail pipeline. So the spam tag is on the email when the calendar event is generated.

Probably because Gmail Spam filtering and Calendar invite processing are handled by different systems. The email itself gets marked as untrusted, but the calendar service still sees the invite as valid structured event data and decides it might be important enough to show anyway. Very distributed systems coded behavior.

Google Calendar sometimes blows my mind. If an invitation to an event is classified as Spam: 1. It is removed from Inbox and filed as Spam ✅ 2. The calendar shows it as a valid invitation 🥶 Why?

@BoazWith @Apple And the latest ChatGPT confidently give a completely wrong description for how these mechanisms work.

Yes, exactly. And the OS APIs are horribly broken. There is no credential to enable a script. Instead the OS allows the user to give Python permission, but only for a single python executable. Trying to give permission to a second one fails without an error message. And to understand which executable has permission, the coding agent needs to use screenshots (it's only visible in the UI). Or find and try all python executables on the platform to see if one works. Debugging Apple's API access control madness is pretty much close to AGI. If only Apple used a simple credential for the local API, that would make life so much easier.

My favorite new prompt to test AI coding agents is: "Write a python scrips that prints GPS coordinates obtained from macOS" @Apple makes this excruciatingly hard. An operating system used to help me do things with my computer. At this point it is an adversarial relationship where I have to fight it for every inch of productivity I am trying to claim.

@BornsteinMatt @Waymo Yeah, I had that happen too.

@appenz @Waymo Really fun variant of this: schedule waymo for 10am, car arrives at 9:50am, waits 5 minutes, leaves

@Waymo It’s really not ok have cars leave before the specified pickup time. Example: - App picks a pickup spot 8 minutes walking distance away - App shows, pickup in 10 minutes, so all good. I can do that. - I start walking towards the pickup spot - …within a minute of me starting to walk, app shows car arriving in 1 minute, I.e. 8 minutes earlier than the previous time. That’s impossible. I can sprint, but I won’t cross 4 lane street during rush hour when the lights are red. - I arrive 3 minutes before the originally agreed to pickup time, but car is already gone and I get charged In this case, it would have bee physically impossible for me to make the pickup due to the walking distance. It’s not fair to make it impossible for the rider to reach the car, and then charge them for missing it.

My bank just launched a CLI. We are definitely living in the age of agents now. @mercury ❤️

@martin_casado Whoaaa... congratulations!!

Congrats to the team for the second NSDI test of time award 💪

Mirelo's exceptional audio model is now available on Runway. It's amazing what difference sound can make for videos.

@oinariiisan @tomochinski The persistence of a true entrepreneur 🙏🥰🤝

In 10 seconds, you’ll witness the pure charm and grit of Tomoko Namba, DeNA’s legendary founder. 　 Who else would relentlessly hunt for a handshake from an a16z partner on a big stage in SusHi Tech? 😂 (Guido being oblivious is the best part.) #STT2026 @tomochinski @appenz

@lishali88 @a16z Wohoo! Welcome Lisha!! 🎉

BIG PERSONAL UPDATE. I've joined a16z as a partner investing in infra and AI. I'm also stepping down as CEO of Rosebud AI. I reflect in this article on my 8 years of building in generative AI. At @a16z I‘ll be focusing on the frontier model stack: the models, and the infra and dev tooling around them. I'm excited about rapid model progress, increasingly driven by AI itself, and about what AI is unlocking for math and the sciences. And I’ll always have a soft spot for AI creative tools, having built them for 8 years.

@NousResearch @Teknium Nous swag is in a galaxy of its own. Respect @Teknium .

Join the Nous Research team for a Hermes Agent Jam with presentations and Q&A Tuesday April 14th, 4PM EST in the Nous Discord

@Mascobot We will miss you Marco, and all the best for your next adventures!

Life update: I've decided to leave a16z. It's been an incredible run. I joined as a Partner about 3 years ago, a very different time in AI timelines. AI was in an early takeoff stage, code hadn't reached its full potential yet, and the RL, robotics, and AI infra landscape was still taking shape. I got to work alongside some of the sharpest founders and AI researchers in tech, backing people working on the most interesting problems. It wasn't an easy decision. I've loved working with every team I've backed and worked with during this time (and I'll keep working and helping them in any way I can). Cursor had just launched in early 2023 when I met Aman co-hosting a few events at academic conferences back when AI coding was still in its early days, and it was clear since then that they were something special. Every company and team has special, from @cursor_ai, @thinkymachines, @bfl_ml, @WaveFormsAI, @deeptuneai, @ShizukuAILabs (and other unannounced ones). I'm incredibly grateful they let me be a tiny part of their journey. I'm also incredibly grateful to @bhorowitz, @martin_casado, @pmarca, @JenniferHli, and @sarahdingwang for trusting me very early on and to the entire AI infra team. This team is genuinely special and the best team founders can work with. What's next? More to come soon on this! This is something I've been thinking about for some time. The progress in AI models, RL, computer-use, robotics, has been staggering, and today we have incredibly powerful tools to work on problems that aren't yet solved and have significant potential at the current pace of progress. To the entire a16z team, thank you!

Heard joke once: VC goes to AI. Says he's confused. Says he doesn't understand startup pitch. Says he feels all alone in threatening world where what lies ahead is vague & uncertain. AI says, 'Simple. Invest if A16Z is investing.' VC bursts into tears. Says, 'But AI…I am A16Z.'

@tferriss 10. Best in class.

Has anyone used Matic (robot vacuum)? If so, from 0-10 (no 7 allowed), how strongly would you recommend and why? Thanks! 🙏