Bergami Lab

Outstanding new work from the Bartos lab! nature.com/articles/s4159…

🚀 We’re hiring! Staff Scientist / Postdoc – Tissue Clearing & 3D Image Analysis (m/f/d) (LMU Munich) Are you a great fit, or do you know someone outstanding, please reach out 🔁 If you want to at the frontier of whole-organ / whole-body 3D imaging, and help generate truly beautiful datasets that drive major biological discoveries and therapeutic development, see below ✨ We’re building the next-generation pipeline for tissue clearing + light-sheet microscopy + quantitative 3D analysis in the SyNergy Excellence Cluster (Mesoscale Hub) and we’re looking for someone excited to push this forward with us. 🧠🔬📈 🎥 I’m also attaching a short video showing the kind of high-quality imaging and datasets you’d be working with. What you’ll do 🛠️ 🔹 Lead and evolve tissue clearing + light-sheet workflows across collaborative SyNergy projects 🔹 Turn complex 3D datasets into robust quantitative insights (visualization, atlas registration, readouts) 🔹 Develop new methods and analysis pipelines together with our AI team 🤖 🔹 Maintain and optimize cutting-edge light-sheet systems (optional: support animal license writing) What we’re looking for 🎯 ✅ Strong hands-on experience in tissue clearing and/or fluorescence microscopy ✅ Solid experience with light-sheet microscopy and 3D imaging workflows ✅ Familiarity with 3D tools like Imaris / arivis Vision4D, stitching (e.g., BigStitcher), and quantitative analysis in cleared tissues ✅ Service mindset, great organization, and strong scientific English How to apply 📩 Apply via the LMU Klinikum online application form lnkd.in/gCgdaJuV Please also send your application to: farida.hellal@med.uni-muenchen.de CC: ali.ertuerk@med.uni-muenchen.de 📎 Include one PDF: short cover letter, CV, 2–3 referees, and earliest start date. 📍 Campus Großhadern (Munich) and Helmholtz Munich | 🕒 Full-time | 📅 Start: 01 January 2026 If you love high-quality imaging, cutting-edge biology, and building something that will matter, we’d love to hear from you. 🌍✨ #hiring #StaffScientist #Postdoc #TissueClearing #LightSheetMicroscopy #ImageAnalysis #SpatialBiology #Neuroscience #SyNergy #LMU #Munich

In vivo CRISPR screen reveals regulation of macrophage states in neuroinflammation @NatureNeuro @LMU_Muenchen nature.com/articles/s4159…

We seek a #PhD student to study the interplay between #gut #metabolism, the #microbiome and #development in #Drosophila. Experience in #omics highly valued! Details in the picture attached. Be part of our group in Heidelberg, Germany campus! Please RT 🙏

New! Online now: Scale-spanning crosstalk between metabolism and information processing dlvr.it/TPKCDZ

📢 📢Delighted to announce our latest pre-print co-led by our fantastic and talented postdocs @IreneFaravelli and @bolanosAnton 👩🏻‍🔬👩🏼‍🔬💪! Human cortical organoids record developmental time for 5 years in vitro. 🧫🧠⏳. A huge collaborative effort, big thanks to all co-authors! 🧵👇

Happy to be part of this truly seminal work by the Pernet-Gally and Volterra labs on astrocyte leaflets and the role of ER (but not mitochondria!) in regulating local Ca2+ transients integrating synaptic activity! cell.com/cell/fulltext/…

Nature research paper: Functional synapses between neurons and small cell lung cancer go.nature.com/41Ne5qi

🧠✨ New preprint! We uncover a brain-specific immune vulnerability in metastasis: the MIF–CD74 axis rewires microglia/macrophages into a pro-metastatic state — and we show how to therapeutically reverse it. 🔗 biorxiv.org/cgi/content/sh…

Functional synapses between neurons and small cell lung cancer | Nature | I am beyond excited to share that our work on innervation of SCLC tumors is finally out. Non of this would have been possible without an entire army of friends and collaborators. nature.com/articles/s4158…

Following malignant transformation, small cell lung cancer cells hijack neuronal synaptic signaling to promote tumor growth @Nature @Stanford @BrighamWomens @humsav @michelle_monje 🇺🇸 nature.com/articles/s4158… @UniCologne 🇩🇪 nature.com/articles/s4158…

Finally out at @Nature! Led together with @LabMotori, @MaxAnstoetz, @RizzoliSilvio, @chr_reinhardt, and Filippo Beleggia, we show that small cell lung cancer hijack glutamatergic synapses for proliferation advantage. Congrats to all involved! @CECAD_ nature.com/articles/s4158…

Can you rejuvenate an old brain by giving it young immune cells? 🧠 My lab @calico put it to the test. In our new study, we replaced the brain's immune cells in old mice with young ones. The result? The old brain environment forced the young cells to age RAPIDLY. A 🧵👇

MitoTracker transfers from astrocytes to neurons independently of mitochondria biorxiv.org/content/10.110…

@Franklandlab Impressive work Paul, congrats!

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested

Excited to share our new study: "Cold memories control whole-body thermoregulatory responses" by @Andrea_MZamora, @Akaron0884 & team at @tcddublin, in collaboration with @lynchielydia & @DrChristineAnnD @RyanLabTCD @Nature nature.com/articles/s4158…

@TheVilchezLab Great news David, congratulations!

Thrilled to announce that our DFG Research Unit on cell-autonomous regulation of proteostasis has been approved for funding! #aging #proteostasis cecad.uni-koeln.de/outreach/news/…

In this week’s @Nature, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n

it was a phenomenal #CancerNeuroscience ⁦@KeystoneSymp⁩ meeting in beautiful Banff. Excellent science, inspiring conversations with wonderful colleagues. Hoping we can meet here again in 2027!

Super excited to share our recent work now out in @Nature! We introduce trans-synaptic tracing tools from circuit neuroscience to study the whole-brain connectome of glioblastoma. nature.com/articles/s4158…