AB

@unusual_whales Maga voter are stupid as shit.

100% of MAGA voters approve of Trump’s current term, per CNN

@tickrSE Tack 🙏

@blackerproduct Lycka till, min dm är alltid öppen 🫡

1/2 LLM gör det möjligt för fler att bygga saker snabbare, även utan djup teknisk bakgrund. Ser många pratar om “SaaS-död”, jag tror snarare att vi kommer se en våg av halvdana system som inte håller i längden.

@tickrSE Har titta på YT men man vet inte om det är bra innehåll förens man tittat klart på videon. Skall testa screens tack för tipset

@blackerproduct Är lite meckigare än webbaserade applikationer och inget som jag ens kan ta över twitter tror jag 😅 för webbaserat tycker jag fly.io är riktigt smidigt. Likadant där, bara beskriv för Codex att du vill hosta på fly.io så löser den hela den biten

@tickrSE har du något tips på starta guide tar jag gärna emot det för det är en djungel. Titta lite på YT men hittade inte mkt vettiga vids..

@tickrSE Loveable skapade något lokalt, men tyckte inte det var toppen för man vill ju inte bara ha tillgång till det lokalt. Jag fick igen koppling till Git via loveable tex. Som du märker är jag ingen programmera. Finns kanske bättre vägar att gå? IDK

@tickrSE Testa många, till och med dragit ner VS Code för att sätta upp en Git och kört Codex via den. Det tog stopp vid koppling mellan VS och Git, satt i några timmar sen orkade jag inte längre. Jag har svårt att gå från ide till något färdigt.

@blackerproduct Vad har du testat? Typ Lovable eller liknande?

@PaulAustin3w @bryan_johnson the word "microdose" is thrown around to much since this dosages varies alot btween users from what i read.

@bryan_johnson This is very interesting data for microdosing psychedelics, since many who microdose will take low doses, consistently, for a long period of time. I’d be curious to see if it had the same impact on motility as the occasional high dose.

Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is a longevity therapy. After seeing the data, we think it is (see reply post for the experiment summary). Also, like most things biology: the results are complicated. My data suggests that the magic mushrooms (psilocybin) negatively impacted my fertility markers. Before the first psilocybin dose my motile sperm count was at 99.6th percentile for men under 25 years of age, it dropped to 77.7% and partially recovered to 89.3% following the first dose, and second doses, compared to the same age cohort (numbers compare similarly to my age cohort as well). 3 days following my second dose (first dose 25 mg, second dose 28 mg) . Motility: dropped 51% . Total count: almost unchanged, dropped by 2% . Total motile count: dropped 52% . Normal morphology: dropped by 50% 20 days post 2nd dose, the pattern continued, with typical latent effects on total sperm counts Motility: recovered back to -2% of pre-psilocybin baseline: . Total count: dropped by 38%, latent effect. . Total motile count: remained inhibited at -39% of pre-psilocybin baseline, (despite motility normalizing, due to the total count drop) . Morphology normalized to -10% of baseline levels. Reduction in free testosterone might have contributed to the effect. While total serum testosterone increased by 30% 3 days following the 2nd dose (neither FSH or LH were meaningfully affected either), and continued to be at 11% above baseline, SHBG increased by 37%, SHBG binds testosterone and reduces its bioavailability and activity. My free testosterone (direct) showed 24% and 23% drops at 3 and 20 days post 2nd dose. In light of the neuroplastic, well-being, brain reset, and systemic metabolic and anti-inflammatory benefits, the trade-off is probably worth it. Especially considering that the magnitude of inhibition has no meaningful effect on actual fertility (total motile counts above 50 million are still on the safe side). This is a first-in-human observation, to our knowledge there is no published human clinical study demonstrating that psilocybin diminishes male fertility markers. General mechanistic evidence exists for recreational and psychoactive drugs possibly inhibiting fertility markers due to their effects on the hypothalamus-pituitary-adrenal axis and general hormonal reset.  Yet no direct evidence for psilocybin or other similar psychedelics inhibiting fertility markers exist. A potential mechanism for the immediate inhibition of motility could involve direct serotonergic signaling in sperm. Human sperm express multiple serotonin receptors, including 5-HT2A, and one recent study found that a 5-HT2A antagonist reduced sperm motility, suggesting that 5-HT2A may regulate motility. Psilocybin is known to bind 5-HT2A with high affinity.

@MysterTradez @DeItaone I don’t think I look into fact. Try a search or ask AI. Us runs on a deficit on oil eg it uses mors than it produces

@blackerproduct @DeItaone That’s what you think?

TRUMP: WE ARE DEFENDING STRAIT OF HORMUZ FOR EVERYONE ELSE

@MysterTradez @DeItaone This guys clearly didn’t educate himself

@DeItaone Because we HAVE oil in America. Nobody understands that.

$QQQ we got the 1st hr bounce... now, the hefty lifting. any RESISTANCE this market has struggled w/ the last 2 weeks... watch $591.33 in QQQ for a turn (or failure)

@klarnaseb Stock trading at 52w lows....

Exciting news! Klarna has now reached 7 million consumers in France That's 1 in 7 French adults App usage up 221% year-on-year France is becoming one of our fastest-growing markets in Europe and we're just getting started. 🇫🇷

@bagholder_ 2/3 är inte fy skam

Ibland vinner man ibland förlorar man, köp sedan 3 månader🫡

@unusual_whales wonder what world these guys are living in? its clearly not the earth

Q: Are we going to have a global oil shock as a result of this conflict? Hegseth: Trump has been clear that he's not allowing that to be a limiting factor

@unusual_whales its pure shit 💩

Trump: "No other president can do some of this shit I'm doing"

@dahlqvistjonas Du glömde att alla måste sätta sig på en cykel för att genera energi åt AI minst 8h/dag.

Fel tänkt! Jag tror till slut att det behövs basinkomst om AI tar över jobben. Men har man en skill factor och kan jobba med något som ger ökad lön utöver basinkomsten, så kommer alla sträva efter detta då det ger ökad lön. Men det kommer inte finnas jobb åt alla!

@DVATW Yet the Dax is ATHs

This is what economic suicide looks like;

@blahblahblah453 @sentdefender in line with this dudes comment on the "minor issue"

@sentdefender Fort Knox is open to take the gold, apart from all the fences and security.

U.S. Secretary of Defense Pete Hegseth states that the Strait of Hormuz is “open for transit” and the only thing preventing that is continued drone and missile attacks by Iran.

@sentdefender "only thing preventing that is continued drone and missile attacks" LOL these guys are delusional

@Investeraren lång väg till IPO kurs

🇺🇸 Klarnas styrelseordförande Michael Moritz har köpt ca 3,47 miljoner aktier under perioden 3 - 11 mars för totalt 49,9 MUSD. Detta efter att aktien tappet -69,2% sen ATH. Aktien +5% i förhandeln #PrataPengar #Finanstwitter