
Eric H Chang
2.7K posts

Eric H Chang
@changsbrain
Neuroscientist | Assoc Professor, Feinstein Institutes @NorthwellHealth @ZuckerSOM | Neuro-immune interactions, bioelectronic medicine, IBD, cancer | Views mine







We recently launched an essay competition for which scientists described structural problems they run into. With nearly 200 submissions, we decided to give out 8 awards, instead of 3. A quick summary here 👇 1 / 5









Next, a superb panel on accelerating the pipeline from bench to bedside. @KevinJTraceyMD emphasized the importance of designing research from the outset with clinical translation in mind. @CliffordF66814 shared the advantage of @NorthwellHealth’s integrated system: in a recent case, they went from FDA approval to first clinical implementation in just 22 days. But it’s not just infrastructure and planning; it also takes courage. As @itchdoctor put it: “When your research is in clinical trials, you’re kind of sweating. Like, is my science going to hold up? But it’s about having the courage to put it out into the real world.”






What if one of cancer’s most devastating side effects could be reversed? Cancer cachexia is a debilitating wasting syndrome that affects many people with cancer, yet treatment options remain limited. Team CANCAN has published new research in @ScienceMagazine that highlights a previously underappreciated driver of cancer cachexia: localised signals from tumours acting directly on sensory neurons. This is a big step toward reframing cancer cachexia as not only a systemic metabolic condition, but also one shaped by tumour–nerve communication. 🎥 @ThalesPapaG, Co-Investigator on team CANCAN and team InteroCANCEption, explains the discovery and what it could mean for patients. Read the full paper: science.org/doi/10.1126/sc… --- Team CANCAN is funded by @CR_UK and @theNCI through Cancer Grand Challenges.







