Chiarle lab

Not easy to encompass the growing importance of #ALK in cancers and the progress in treating ALK+ tumors, but this Review might help @chiarlelab @NatureRevCancer @BostonChildrens @unito bit.ly/3XV09bO

These experiments reveal the full extent of DNA damage caused by L1 expression. The retroelement that built our genome wreaks havoc, too. Powerful implications for cancer biology. Beautiful collaboration with Alice Lee’s and CZ Zhang’s labs. @DanaFarber

Our latest publication online now! rdcu.be/dSvhN @NatureComms Amazing team work @lab_santamaria @MJNokin @BiagioRicciutMD @DrMarkAwad @NadalErnest @cereda_lab

@chesscom No

what do you think?

Very exciting opportunity to join the faculty ⁦@BWHPath⁩ : bwh pathology professsor opening - Google Search ⁦⁦ #fpstate=tldetail&htidocid=a794LOFMZESFpb_tAAAAAA%3D%3D&htiq=bwh%20pathology%20professor%20opening&htivrt=jobs" target="_blank" rel="nofollow noopener">google.com/search?q=bwh+p…

Fantastic collaboration with @maddanilo and the @genentech team for our review on SHP2 just out @CD_AACR doi.org/10.1158/2159-8…

Thanks a lot @CICancer_com for hosting the first RAS Initiative Europe event #TargetingRAS, we enjoyed three days of amazing science! @KRASKickers @FredNatLab #KRAS

Check out our paper on @ScienceTM that deciphers how to overcome ALK TKIs resistance in ALK+ lymphoma by targeting the CCR7-PI3Kgamma pathway. Congrats to all the talented scientists that helped the work! It's on the cover! @BostonChildrens @unito science.org/toc/stm/15/702

Many others contributed, including many current and former members of my lab, especially @isidrolauscher. Taek from the Roberto Chiarle's lab (@chiarlelab) performed the experiments, my illustrious collaborators Steve Elledge and David Pellman provided insightful comments.

It is such an honor for us to partner with @ALK_Research & @ALKLungCancer to fund research most meaningful to the ALK community. Thank you, @DrMarkAwad, @IbiayiMD, @chiarlelab, Dr. Raphael Nemenoff, Dr. John Iafrate, and @LironBarPeled for your commitment to research #LCSM

A caution on CRISPR in @NatureComms, and the suggestion that base editing and prime editing may be safer from @jianli_tao, Roberto Chiarle, et al. ms.spr.ly/6017b40J9 #mobileelements #jumpinggenes

Our work on LINE-1 insertions at CRISPR editing sites is already out! Congratulations to Jianli Tao (@jianli_tao) and Qi Wang (@flying_gene) @chiarlelab. Many thanks to our collaborators from @KathleenHBurns to help to make it possible.

Jonathan Riess says that the future of immunotherapy in mutation-driven lung cancer is vaccines - I hope this pans out, for patients' sake! Exciting ongoing trials in both EGFR and ALK #TTLC22

*Karaca-Atabay et al.

Nice comment about our recently published paper in @BloodJournal from Karaka-Atabay et al. Thanks to Dr. Ryan Wilcox for highlighting our work.

Nice comment about our recently published paper in @BloodJournal from Karaca-Ataby et al.@atabay_karaca Thanks to Dr. Ryan Wilcox for highlighting our work.