Crash

99 posts

Crash

Crash

@crashlib

Katılım Kasım 2022
609 Takip Edilen60 Takipçiler
Crash
Crash@crashlib·
@APKoz47 @BrandynsWisdom @grok Way to cherry pick bro. He meant overall as a congressman. @grok - who was the congressman least likely to vote with Biden during his presidency?
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Aaron
Aaron@APKoz47·
@BrandynsWisdom @grok has Thomas Massie voted 90% with republicans since the latest congress took office in 2025
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Brandyn's Wisdom 🗽
Brandyn's Wisdom 🗽@BrandynsWisdom·
79% of Thomas Massie's funds came from Democrat PACs. Stop pretending this guy was a conservative.
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Crash@crashlib·
@ChrisLoesch @grok @SStricklandMMA @SKIPdaZIP No one said anything about rights. Putting the interests of another nation above those of the US is problematic. But go ahead, defend foreign aid, reckless wars, and funding a genocide.
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Sean Strickland
Sean Strickland@SStricklandMMA·
It has nothing to do with Thomas Massie losing, It has everything to do with a foreign government and it's supporters lobbying 30 million to protect its interest of a foreign government. This isnt America first. Im more committed to never vote for an aipac candidate again.
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Crash@crashlib·
@ChrisLoesch @grok @SStricklandMMA @SKIPdaZIP Hey @grok, having Israeli influence isn’t just about AIPAC though. How did AIPAC related groups contribute to Massie’s opponent’s campaign? What about Miriam Adelson, Paul singer, and John Paulson? Are any of them supporters of Israel or Jewish?
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Roger Seheult, MD
Roger Seheult, MD@RogerSeheult·
Thank you for underlining the point. Hep B vaccination in this country reduced the incidence so low that the majority of new cases were from individuals not born in this country. Precisely the point that I was making about NNT, ARR, and why NNT would go up as the prevalence goes down.
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Crash
Crash@crashlib·
Here’s a little story about what we’ve been going through here in Sacramento. Thanks to leaders like Gavin, the crime has gotten completely out of control. It’s to the point where running a business in certain areas is near impossible. Most recently, a homeless guy and his friends have been using the roof access ladder, which has a locked guard on it to deter use, to get on the roof and live up there. The first thing I see from our rooftop residents is the numerous piles of shit all over the place. If you aren’t familiar with homeless shits, imagine what a steady diet of AMPM desserts, snacks, and soda produces at the back end. It’s a site to see. They also vandalized the venting systems, broke into HVAC closets, broke windows, and used the roof as a storage unit for all their stolen items. And you would be shocked at how much these guys steal. They constantly bring building signs, bags full of other people’s stuff, and new bikes to the property. We fill up the big trash every single week with stuff that used to be someone else’s, or possibly even yours. Cars are broken into all the time in the parking lot, and a few years ago they even lit part of the building on fire. We’ve called the sheriff about 30 times. Recently, we’ve had one guy trespassed multiple times, but he’s out and back at the property in less than 12 hours every time. Most of the calls the cops can’t do anything. They say their hands are completely tied and that there’s not much they can do. Even if they bring a guy in for breaking the law, he’s let out with a slap on the wrist. In this video Gavin says 9,000 arrests. But, those arrests mean nothing if those people are back on the street raising hell later that day. Now there’s an encampment in the empty lot down the street. I posted up for an hour the other day and got to see them make drug deals, throw trash all over the place at multiple buildings, harass people, and basically ensure that the area continues to become even more of a dumpster fire. I always hear people talk about why everything is so expensive now. People rarely mention all the downstream effects all this crap brings about. All the repairs, clean up, higher insurance premiums, higher rents, and man hours that go into dealing with this problem means everything gets more expensive. I’ll wrap this up with a request: never forget that this guy cleaned up San Francisco in a snap for a foreign leader. Never forget that your tax dollars fund the insane amount of fallout that comes from letting unhinged criminals and people dealing with drug addictions do whatever the hell they want. Never forget who is responsible for turning so many neighborhoods into dangerous, crime ridden hellholes.
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Governor Gavin Newsom
Governor Gavin Newsom@CAgovernor·
California is expanding @CHP_HQ teams in key regions to bring down crime. We've seen what success looks like when investing in strategic community partnerships, and with this next phase, we're continuing the work to improve public safety throughout the state.
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DataRepublican (small r)
DataRepublican (small r)@DataRepublican·
This is a strange poll, thanks for humoring. If you could press a button, and it killed 10,000 people now violently, but resulted in the abolition of war forever, potentially saving an infinite number of lives, would you press it?
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Crash
Crash@crashlib·
@ufc @DustinPoirier Dustin is jumping gilly in rd 3. Perfect ending to an incredible career.
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Crash
Crash@crashlib·
@honestpollster @elonmusk Step 1: don’t backstab Elon Step 2: follow through on promises Step 3: no America party formation Because they couldn’t do 1 and 2, they get 3
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World of Statistics
World of Statistics@stats_feed·
🇺🇸 If you could give one piece of advice to Donald Trump, what would it be?
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Crash
Crash@crashlib·
Why Compare Nicotine to Arsenic in Arguments? Such comparisons often arise in debates about smoking or nicotine’s safety, typically as a rhetorical tactic to exaggerate dangers and discourage use, even if the equivalence is flawed. Here’s why someone might employ it: • False Equivalence for Persuasion: By likening nicotine to arsenic—a notorious poison used in rat killers and linked to severe toxicity—arguers aim to evoke fear and moral outrage. For instance, anti-smoking campaigns highlight that cigarettes contain arsenic (among 7,000 chemicals), implying smoking is akin to “ingesting rat poison,” which indirectly taints nicotine by association. This guilt-by-association tactic simplifies complex science: while arsenic in smoke contributes to cancer, nicotine itself isn’t the carcinogen, but the comparison makes nicotine seem equivalently deadly to “win” by emotional appeal rather than nuance.       • Exaggerating Toxicity: Some claim nicotine is “more dangerous than arsenic” based on outdated LD50 estimates, positioning it as a “poison” to counter claims of benefits (e.g., cognitive enhancement). This ignores nicotine’s therapeutic uses and arsenic’s lack of addiction or stimulant effects, but it sways audiences in heated debates by invoking hyperbole.   • Dismissing Benefits via Historical Parallel: Both have been used medicinally—arsenic for syphilis/psoriasis (now avoided due to risks), nicotine for cessation/cognition. Opponents might say, “Arsenic was once ‘beneficial’ too, but it’s poison,” to undermine nicotine’s responsible use (e.g., gum) by suggesting any “benefit” is outweighed by risks, akin to promoting a toxin.    • In Debates on Harm Reduction: Pro-nicotine voices (e.g., vaping advocates) clarify nicotine isn’t the killer—it’s tar/arsenic in cigarettes—while critics blur lines to argue all nicotine products are “poisonous.” Recent X posts echo this: one notes vaping’s lower harm vs. cigarettes due to absent arsenic, while another debates health comparisons.     This tactic “wins” by oversimplifying—equating an addictive stimulant with potential upsides to a pure carcinogen—prioritizing stigma over evidence, common in public health or policy arguments where nuance loses to soundbites.
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Roger Seheult, MD
Roger Seheult, MD@RogerSeheult·
Arsenic is generally considered toxic, but it does have some specific benefits in controlled medical or industrial contexts. Here are the main benefits: 1. Medical Uses (Controlled) Treatment of acute promyelocytic leukemia (APL) Arsenic trioxide (Trisenox) is FDA-approved for APL treatment when other treatments fail or in combination therapy. It induces apoptosis and differentiation in malignant cells. Historical antimicrobial use Compounds like arsphenamine (Salvarsan) were used to treat syphilis before penicillin was developed. 2. Potential in Parasitic Infections (Historic) Used in the past for treating trypanosomiasis (sleeping sickness) with arsenic-based drugs such as melarsoprol. Still used in limited settings despite toxicity due to lack of alternatives. 3. Industrial and Agricultural Uses Wood preservation Chromated copper arsenate (CCA) was used to preserve wood from rot and insects, though phased out in many countries due to toxicity concerns. Pesticides Arsenic compounds were historically used as pesticides and herbicides, though safer alternatives have largely replaced them. 4. Potential Anti-Cancer Research Research is ongoing into arsenic nanoparticles for targeted cancer therapy, leveraging its toxicity in cancer cells while sparing normal tissues when encapsulated properly. Just like Nicotine, I would never recommend arsenic to anyone to ever use unless there were clear benefits that out weighed the risks. ⚠️ Note: While there are benefits in very specific and controlled applications, arsenic remains highly toxic and carcinogenic, and environmental or dietary exposure should always be minimized. Let me know if you want mechanistic details on arsenic trioxide’s action in leukemia for your pharmacology reviews.
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Chief Nerd
Chief Nerd@TheChiefNerd·
Tucker Carlson on the Health Benefits of Nicotine “I'm never sick … I was on TV for 29 years. How many shows did I miss? None.”
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Crash@crashlib·
For anyone looking for a complete picture on nicotine, it can actually have positive effects as well. Below is some of the good, as written by Grok 4 One thing I’ve learned over the years is that nicotine, much like caffeine use, are not one size fits all. Individual genetic makeup, in addition to many other factors, will impact your experience. — COGNITIVE ENHANCEMENT Nicotine can act as a stimulant for brain function, potentially improving focus and mental performance in healthy adults or those with certain conditions. • Improved Attention and Alertness: It enhances alerting and orienting attention, making it easier to concentrate on tasks. This is mediated by nicotinic acetylcholine receptors (nAChRs) in the brain, which boost neurotransmitter activity like dopamine and acetylcholine. Studies show benefits in non-smokers and minimally deprived smokers, with effects on visuospatial attention and top-down control.      • Better Memory and Learning: Nicotine supports working memory (short-term recall) and episodic memory (long-term events). For example, it can improve performance on memory tasks via mechanisms like enhancing long-term potentiation (LTP) in the hippocampus. In animal models and human trials, low doses have shown activating effects on cognition.        • Fine Motor Skills and Processing Speed: It may boost hand-eye coordination and reaction times, useful for tasks requiring precision.     These effects are why some people use nicotine products for productivity or in high-focus professions, though they’re more pronounced in those with baseline deficits (e.g., ADHD).  NEUROPROTECTIVE & DISEASE-SPECIFIC BENEFITS Nicotine shows promise in protecting brain health and managing certain neurological conditions. • Potential Protection Against Parkinson’s Disease: It may reduce the risk of developing Parkinson’s by inhibiting enzymes like SIRT6, which promotes neuron survival and reduces apoptosis (cell death). In studies, it improves dyskinesia (involuntary movements) and memory impairment in Parkinson’s models.     • Support for Alzheimer’s Disease: Nicotine can alleviate cognitive decline by activating pathways like PI3K/Akt for neuronal survival and desensitizing α7 nAChRs to restore LTP, a key process for memory. Human studies show shifts in brain activity toward normal levels in Alzheimer’s patients.     • General Neuroprotection: It may shield against neuronal degeneration, enhancing cognitive performance in aging or disease states.  ANTI-INFLAMMATORY EFFECTS Nicotine can modulate the immune system, potentially benefiting inflammatory conditions. • Reduction in Inflammation: Through the cholinergic anti-inflammatory pathway, it lowers pro-inflammatory cytokines (e.g., TNF-α, IL-6) and promotes protective autophagy. This is seen in conditions like ulcerative colitis (improving gut symptoms), arthritis (reducing joint swelling), sepsis (enhancing survival), and obesity-related inflammation (improving insulin sensitivity).    • Other Inflammatory Benefits: May help with multiple sclerosis, myocarditis, pancreatitis, allergies, and even tissue repair in low doses.  MOOD & METABOLIC BENEFITS • Mood Improvement and Creativity: By enhancing attention and dopamine release, it can elevate mood, reduce stress responses, and boost creativity or wakefulness.    • Weight Management: Suppresses appetite and may aid weight loss or improve insulin sensitivity, though this isn’t a primary recommendation.
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Roger Seheult, MD
Roger Seheult, MD@RogerSeheult·
As a pulmonologist who takes care of people with lung problems for a living, and also takes care of people in the intensive care unit, using the idea that a substance is natural therefore is OK to put inside of your body is mind blowing. Here’s what smokeless nicotine does •Increased heart rate •Increased blood pressure •Constricted blood vessels (vasoconstriction) •Impaired brain development in adolescents •Reinforced addiction pathways (strong dependence) •Withdrawal symptoms (irritability, anxiety, poor concentration, cravings) •Possible insulin resistance (higher diabetes risk) •Gastrointestinal issues (nausea, increased acid production) Please do not consume nicotine.
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Crash
Crash@crashlib·
@mtracey Always give up when things don’t go your way. Only trust people who are right 100% of the time. Never change your mind and never adopt a new position.
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Michael Tracey
Michael Tracey@mtracey·
Musk: the government reform initiative I just spent months manically championing turned out to be pointless, and I became the USA's top campaign donor of 2024 to elect a party and president I now repudiate. But be sure to support my next well-considered political initiative
Elon Musk@elonmusk

@heydave7 What the heck was the point of @DOGE if he’s just going to increase the debt by $5 trillion??

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Crash
Crash@crashlib·
In addition to that, Topuria’s performance and post fight interview stole the spotlight from Pantoja. There’d be a much bigger conversation around Pantoja if he would’ve been on a different card. Does feel like UFC likes to focus on only a few stars at a time. Topuria is in that group. Jones was. Pereira was.
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Crash
Crash@crashlib·
Methylated B vitamins, TMG, and higher doses of magnesium (malate in AM & glycinate/threonate PM) fully cured my anxiety. I’m a much, much calmer person now. Before that I had tried vipassana mediation, kava, at least 20 supplements, and everything else under the sun. I recommend identifying your mutations to understand what you need and why in addition to what should be avoided. Enzymes are also highly underrated for when your stomach is upset or you’ve eaten like a trash can. Dihydromyrecetin is effective at reducing hangover symptoms.
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World of Statistics
World of Statistics@stats_feed·
Has anyone actually noticed any differences after taking daily vitamins, if so what?
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Larry Kudlow
Larry Kudlow@larry_kudlow·
Let me add my voice to a cooling off rapprochement between @elonmusk & @realDonaldTrump. The country needs Musk genius & Trump leadership policy program. America First.
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Crash
Crash@crashlib·
@hubermanlab This answer would work if almost every restaurant didn’t use seed oils. Regardless of the complexity and what side of the debate you’re on, this should be sorted out.
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Andrew D. Huberman, Ph.D.
Andrew D. Huberman, Ph.D.@hubermanlab·
My solution to the seed oil debate. Easy. Replace with olive oil and (if you eat animal based products (which I do) some (limited) butter and ghee. It’s not complicated. The debate isn’t real because there are too many variables. The foods seed oils are usually combined with etc.
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Crash
Crash@crashlib·
@ufc My presale access code says invalid and there’s no option or link to support. This happened last time. How do I get this resolved?
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Liv Boeree
Liv Boeree@Liv_Boeree·
Two days ago I launched a donation matching challenge to fight against corporate torture of US farm animals. The first $50k has been filled, so I am extending the challenge to $75k to help pay for a second campaigner. Wondering what the hell I'm on about? WATCH THIS 👇
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Speaker Mike Johnson
Speaker Mike Johnson@SpeakerJohnson·
House Republicans will not tolerate adversarial regimes, like the Chinese Communist Party, using propaganda to manipulate students, undermine academic institutions, and compromise national security. Higher education in America must remain free from foreign malign influence. I commend @RepPfluger for his leadership in protecting students and ensuring taxpayer dollars are not used to fund institutions that host Confucius Institutes or maintain ties to Chinese entities supporting CCP interests.
Speaker Mike Johnson tweet media
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