David Christian, Ph.D.

.@iancohn @striepenlab @KingOfPathogens et al. show that intestinal cDC1s have distinct roles in shaping CD4+ T cell responses to #Cryptosporidium. hubs.la/Q02TJsqr0 📘 In our #Cytokines collection: hubs.la/Q02TJtq20 #cytokines2024

Kevin Wood was a wonderful human being and he is gone way to soon, like a shooting star. I will miss him. Support Future Biophysicists in Kevin's Memory gofund.me/b8bff582

It still hasn't sunk in that I was at the "old folks" table for dinner...

Taking a trip down memory lane today ⁦@Penn⁩

Delighted to have my image on the cover of @mbiojournal Isn't the #intestine pretty?! Want to see more? Check out our publication that goes with it! @striepenlab @KingOfPathogens journals.asm.org/doi/10.1128/mb…

Preview of some great Global Parasitology Seminars to look forward to this coming semester! @TrendsParasitol @BSPparasitology @AS_Para @parasitesrule @AmSocParasit @ParaFrap @pennbgs @womeninmalaria @pennvet @bloodSparasites @PiParasitology

Hey @jkagan1 who likes cytokines and mRNA vaccines? @emilyaunins @anthonyphan with @MgAlameh @dachri0 @KedlRoss @WeissmanLab explore how IL-12 mRNA can be used to diversify and improve mRNA vaccine induced CD8 T cell responses - takes a village biorxiv.org/content/10.110…

Check out our new paper for a window into Cryptosporidium's life in the gut #cryptosporidium #intestine #MicroscopyMonday

Read our new paper: Cryptosporidium impacts epithelial turnover and is resistant to induced death of the host cell by @BethanWallbank out today in @mbiojournal. Great team effort with @RyanPardy2 @KingOfPathogens @BrodskyIgor journals.asm.org/doi/10.1128/mb… Infected = not apoptotic:

New record for the lab (and not a good one). Revision of latest manuscript contains 79 new figure panels to address reviewers’ questions. To quote Hidde Ploegh: End the tyranny of reviewer experiments!

In its 184 year history @JExpMed has not published a manuscript on Cryptosporidium. Today, an injustice righted with @iancohn and @striepenlab using transgenic parasites to understand how cDC1s regulate T cell–mediated resistance to Cryptosporidium rupress.org/jem/article-ab…

Why do activated T/B cells wait to divide? Why is there heterogeneity in their daughter cell responses? How do we find peace in these troubled times? Check the Bailis Lab’s FIRST PAPER (🎉) for insight into 2 of these 3 questions! science.org/doi/10.1126/sc…

Hannah: “Daddy, do you know Disneyworld?”

@jueberhard @KingOfPathogens

1/ 🚨Pre-print Alert! 🚨 We (@KingofPathogens) are excited to share this story about immune recognition of latent T. gondii cysts in the CNS, and the role of this stage in persistence. A (n almost) brief thread: biorxiv.org/content/10.110…

⚡️New preprint out! #Immunology #biophysics 1/ We show hidden functional immune cell states based on collective membrane properties, which are not directly visible via cell surface markers. biorxiv.org/content/10.110…

@LeventalLab Won and covered. Haha.

@dachri0 How’s it go?

So conflicted…not really.

@LabRaghavan @bmentamu @SabrinaVH_ @RicGottardi She did a great job!

So proud of @bmentamu grad student @SabrinaVH_ for giving her talk excellently at #IMES2023 ! Thanks for capturing @RicGottardi 💕

Who likes enteric pathogens and the DC and CD4 T cells that control them? @iancohn and @striepenlab find a role for DC1 in supporting CD4 responses to Crypto. Terrific use of transgenic parasites to track priming, effector responses and parasite control. biorxiv.org/content/10.110…

@JustinPerryPhD @KingOfPathogens @elsanchez09 Can confirm it was stolen from David Artis’s lab.

@KingOfPathogens @elsanchez09 Bahahaha. Does that say "Fartis"???

Hey mammalian cell culture folks! What are your favorite bench top cell counters? Least favorite? We are trying to figure out what to purchase for live/dead counts using trypan or something similar. Thanks for your advice!