DeFrate Lab

@BethanyAndoko @thehopefulscie1 @KelseyHCollins @TiffanyTKP @prismtjandra @UCSFOrthosurg @KristineGodziuk What a great talk! Awesome job, Hope!!

Ended a jam-packed day at #ORS2025 with talks from @thehopefulscie1 and others to discuss interdisciplinary approaches to solutions for OA👏 I am constantly inspired by Hope, who presented on the metabolome of knee OA patients following 18-mo weight loss interventions #ORSSMC

Starting #ORS2025 with a phenomenal talk from @SadeWill93 on how #aging and the immune system alter and magnify IVD in both males and females, and more so, how #pain fits into this complex relationship 👏🏼🧬

@URochester_SMD @LoiselleLab @docwilson13 Congrats!! Awesome news!!

With new NIH funding, @LoiselleLab and @docwilson13 will study ways to prevent and treat abdominal adhesions, a complication affecting more than 50% of abdominal surgery patients. 🗞️ urmc.info/1Vb #URochesterResearch

We are looking forward to seeing everyone at #ORS2025. Come check out our work! @ORSsociety @OrsMeniscus @DukeOrtho @DukePathDept

Congratulations to our newest PhD candidate, @allisonrbinsn, on her successful prelim yesterday! Thankful to have such a beautiful day to celebrate today. @DukePathDept @DukeOrtho

@JasonCMarvin @galloway_lab @HMS_DICP @MGHCFD Congratulations, Jason!

There's a lot of work to be done as a result of the new administration, but I'm celebrating the small wins this week 🥲 Thankful to my advisor @galloway_lab, @HMS_DICP Fellowship Director, and mentees for nominating me for the 2024 @MGHCFD Outstanding Research Fellow Award 🥲

@Farsh_G @AliSavadipour @Guilak_Lab @WashUengineers @wustlcrm @WashUMedOrtho @ShrinersStLouis @washu_ortho_res Congratulations!!

Congrats to Gabi Marushack and @AliSavadipour & team for our latest @Guilak_Lab paper showing that polyunsaturated fatty acids alter cell membrane properties & inhibit chondrocyte #mechanotransduction by #Piezo1 and #TRPV4. faseb.onlinelibrary.wiley.com/doi/10.1096/fj…

@RandlesLab Congratulations!!

I am incredibly honored to receive the Presidential Early Career Award for Scientists and Engineers (PECASE), the highest recognition from the U.S. government for early career researchers. This award is a reflection of the collective efforts of so many—my brilliant students, supportive mentors, dedicated collaborators, and the NSF program officers who believed in our vision. Your contributions have been instrumental in advancing our work in computational modeling and digital twins. Thank you for making this journey possible. I’m excited for what we will achieve together in the future! #PECASE #DigitalTwins #HPC #Teamwork #Gratitude @DukeEngineering Read more: whitehouse.gov/ostp/news-upda…

The first paper from PhD student @MaxineOlson27 is out. She developed an algorithm to distribute a ground reaction force into multiple vectors to allow for calculation of midfoot and ankle moments using standard clinical gait lab equipment. sciencedirect.com/science/articl… @MU_MCW_BME

@RicGottardi @USCIS @pennbioeng @PennMedicine @Penn @CHOP_Research @ChildrensPhila Awesome, congrats! What a great picture!! Happy holidays, my friend!

A nice way to wrap up the year is becoming a US Citizen! #newUScitizen @USCIS @pennbioeng @PennMedicine @Penn @CHOP_Research @ChildrensPhila

Congrats @thehopefulscie1 Avery and @ronjune2 on a comprehensive and exciting review!

It is great to finally share our systematic review on structural extracellular matrix components in soft tissues in osteoarthritis! Congratulations to my co-authors Iwan Raza and @Sarah_JB_S. boneandjoint.org.uk/Article/10.130…

@jill_beveridge @Brown_BME @BrownOrthoRes @FlemingLab_ACL Such a great visit!! Thanks so much for having me!

We had the pleasure of having Dr. DeFrate visit us last week to present @defratelab's work towards understanding in vivo cartilage and ACL function. Thank you @Brown_BME, @BrownOrthoRes, and especially @FlemingLab_ACL for hosting! #ACL

Check out our comprehensive transcriptomic comparison of inner and outer zone meniscus tissue to cartilage and passaged meniscus cells to identify meniscus specific genes @SciReports. nature.com/articles/s4159… @DukeOrtho @KaileenFei @DaDchasse @nnakelly2

Check out our latest paper in @FrontBioeng showing that healthy but not osteoarthritic meniscus-derived matrix scaffolds can promote ex vivo meniscus repair. This was a great collaboration with our clinical colleagues @DukeOrtho @FirooziSaman @DaDchasse frontiersin.org/journals/bioen…

@Farsh_G @CytexOrtho Congrats!!

Fantastic news that @CytexOrtho has received FDA approval for a first-in-human Phase I clinical trial for our 3D woven hip implant! Incredible work by our entire team to reach this milestone. massdevice.com/cytexortho-fda…

Excited to be representing @jboerckel and the future Panebianco Lab™️ at #BMES2024!

@meagmac1 @PittEngineering @HangLinLab @BethelMRC Congratulations!!

news.engineering.pitt.edu/bioengineering… Grateful to have so much support from @PittEngineering @HangLinLab @BethelMRC

Congrats Kelsey Collins, PhD @ucsfmskcenter @UCSFOrthosurg for incredible achievements in osteoarthritis research! Awarded NIH Director’s New Innovator Award w $1.5M in funding, she's pioneering therapies to combat musculoskeletal pain and inflammation. tiny.ucsf.edu/kc