Christopher Deppmann

A neural circuit through which small-molecule GLP1RAs modulate reward processing, with implications for the treatment of substance-use disorder and binge eating @Nature @deppmann @GulerLab @LizzieGodschall @bugragungul @isabellesajonia @UVA nature.com/articles/s4158…

NEWS: Oral small-molecule GLP-1 drugs penetrate deep into the brain to suppress cravings. 🧠 Read the full story ➡️ nih.gov/news-events/ne…

Out in Nature today: how next-gen GLP-1 drugs cut cravings, not just hunger. Congrats to co-first authors Lizzie, Bugra, and Isabelle in @GulerLab lab traced the circuit — drug → central amygdala → less dopamine in reward circuits. Mostly Ali's lab; we got to contribute. Proud of this team. rdcu.be/fhfOm #neuroscience #UVA

May the fourth be with you

Congratulations Raymond E. Keller of @MedicineUVA, newly inducted #NASmember! #NAS163 #cellbiology

this is insane a high school student built a beautiful 3D interactive chemistry app

This is work by Jonathon Sewell in collaboration with @zunderlab and the brilliant Bettina Winckler.

You thought you knew everything about BDNF signaling in the spinal cord? Think again. Our new preprint uses highly multiplexed single-cell signaling mass cytometry to show that the same receptor profile can mean very different things in different cells.

🚀 Hiring in Boulder! Starting my lab at CU Boulder (MCDB) this summer and hiring a PRA (Research Technician/Lab Manager) + Postdoc. We study neural circuit assembly in Drosophila dombrovski-lab.org Contact me before applying. Links in first reply 👇

Awesome news. So well deserved! Congrats David!

Congratulations to David and Patrick - two pioneering scientists in the touch and pain field whose work has opened up and facilitated the work of so many others.

Thrilled to see #HHMIInvestigator — & now '26 @BrainPrize winner — David Ginty recognized by The Lundbeck Foundation for his pioneering work on the cellular architecture of touch & pain, which paved the way for a new generation of targeted pain therapies bit.ly/4sbowiN.

Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain. @hhmi_science #Neuroscience #BrainPrize2026

Thrilled to share that I’ll be starting my lab in the Kresge Hearing Research Institute @UMichOto in May! We study how the brain turns gravity signals into stable movement → zhulab.fish (yup, proudly a #zebrafish lab🐟) If you're interested, get in touch! #newPI

AlphaGenome is out in @nature today along with model weights! 🧬 📄 Paper: nature.com/articles/s4158… 💻 Weights: github.com/google-deepmin… Getting here wasn’t a straight path. We sat down @googledeepmind to discuss the story behind the model, paper & API: youtu.be/V8lhUqKqzUc

Sympathetic functional units encoded by genetically defined postganglionic neurons: Neuron cell.com/neuron/fulltex…

Now online! SARM1 senses dsDNA to promote NAD+ degradation and cell death dlvr.it/TNstLg

Large transient assemblies of Apaf1 constitute the apoptosome in cells: nature.com/articles/s4146…